Výsledky vyhledávání - "Bernadette Gruber"

Akademický článek

Development of an In Vitro Biopotency Assay for an AAV8 Hemophilia B Gene Therapy Vector Suitable for Clinical Product Release

Autor: Johannes Lengler, Sogue Coulibaly, Bernadette Gruber, Reinhard Ilk, Josef Mayrhofer, Friedrich Scheiflinger, Werner Hoellriegl, Falko G. Falkner, Hanspeter Rottensteiner

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 581-588 (2020)

Gene therapy product release requires reliable and consistent demonstration of biopotency. In hemophilia B vectors, this is usually determined in vivo by measuring the plasma levels of the expressed human factor IX (FIX) transgene product in FIX knoc

Externí odkaz: https://doaj.org/article/385fb00f577f4457ac3b71706cbf6f70

Zobrazit plný text záznamu

Akademický článek

Persistence of circulating ADAMTS13-specific immune complexes in patients with acquired thrombotic thrombocytopenic purpura

Autor: Silvia Ferrari, Kristina Palavra, Bernadette Gruber, Johanna A. Kremer Hovinga, Paul Knöbl, Claudine Caron, Caroline Cromwell, Louis Aledort, Barbara Plaimauer, Peter L. Turecek, Hanspeter Rottensteiner, Friedrich Scheiflinger

Publikováno v: Haematologica, Vol 99, Iss 4 (2014)

Anti-ADAMTS13 autoantibodies are the main cause of acquired thrombotic thrombocytopenic purpura. Binding of these antibodies to ADAMTS13 eventually results in the formation of antigen-antibody immune complexes. Circulating ADAMTS13-specific immune co

Externí odkaz: https://doaj.org/article/6088089c03124975a2c1d1ed3b9c8981

Zobrazit plný text záznamu

Development of an In Vitro Biopotency Assay for an AAV8 Hemophilia B Gene Therapy Vector Suitable for Clinical Product Release

Autor: Sogue Coulibaly, Friedrich Scheiflinger, Josef Mayrhofer, Hanspeter Rottensteiner, Reinhard Ilk, Werner Hoellriegl, Bernadette Gruber, Falko G. Falkner, Johannes Lengler

Publikováno v: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 581-588 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb849e8599c86f72ce720421abe2e77
http://europepmc.org/articles/PMC7139127

Zobrazit plný text záznamu

Differences regarding the five-factor personality model in patients with subjective cognitive decline and mild cognitive impairment

Autor: Evelyn Berger-Sieczkowski, Bernadette Gruber, Johann Lehrner, Elisabeth Stögmann

Publikováno v: Neuropsychiatrie

Summary Personality and dementia are connected in different ways. A broad knowledge about personality and prodromal stages of dementia might be helpful to identify dementia as early as possible. Hence, personality differences between three cognitivel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5ba5e397d7f4d92064983a70699bad
https://doi.org/10.1007/s40211-018-0292-z

Zobrazit plný text záznamu

DNA interactions and photocatalytic strand cleavage by artificial nucleases based on water-soluble gold(III) porphyrins

Autor: Norbert Müller, Martin Haeubl, Wolfgang Schoefberger, Bernadette Gruber, Lorenz Michael Reith, Günther Knör, Uwe Karner

Publikováno v: JBIC Journal of Biological Inorganic Chemistry. 14:1037-1052

The novel gold porphyrin complex (5,10,15-tris(N-methylpyridinium-4-yl)-20-(1-pyrenyl)-porphyrinato)gold(III) chloride, [Au(III)(TMPy3Pyr1P)]Cl4, was prepared and characterized by optical spectroscopy, high-resolution nuclear magnetic resonance (NMR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c1cc167a320b5ac79abecb2dc05fa1
https://doi.org/10.1007/s00775-009-0547-z

Zobrazit plný text záznamu

A novel flow-based assay reveals discrepancies in ADAMTS-13 inhibitor assessment as compared with a conventional clinical static assay

Autor: Susanna Skalicky, Rana Grillberger, Paul Knöbl, F. Scheiflinger, Peter Turecek, Gerald Schrenk, Bernadette Gruber, Hanspeter Rottensteiner, Barbara Plaimauer

Publikováno v: Journal of thrombosis and haemostasis : JTH. 12(9)

Summary Background Several static Bethesda-type assays are routinely used to determine ADAMTS-13-neutralizing autoantibodies in acquired thrombotic thrombocytopenic purpura (TTP), but the inhibitory activity of these antibodies has not been thoroughl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5c2118189effe3a30978a9fd967946
https://pubmed.ncbi.nlm.nih.gov/25040659

Zobrazit plný text záznamu

Persistence of circulating ADAMTS13-specific immune complexes in patients with acquired thrombotic thrombocytopenic purpura

Autor: Johanna A. Kremer Hovinga, Caroline Cromwell, Silvia Ferrari, Paul Knöbl, Claudine Caron, Barbara Plaimauer, Kristina Palavra, Friedrich Scheiflinger, Peter Turecek, Louis M. Aledort, Hanspeter Rottensteiner, Bernadette Gruber

Publikováno v: Ferrari, Silvia; Palavra, Kristina; Gruber, Bernadette; Kremer Hovinga, Johanna Anna; Knöbl, Paul; Caron, Claudine; Cromwell, Caroline; Aledort, Louis; Plaimauer, Barbara; Turecek, Peter L.; Rottensteiner, Hanspeter; Scheiflinger, Friedrich (2014). Persistence of circulating ADAMTS13-specific immune complexes in patients with acquired thrombotic thrombocytopenic purpura. Haematologica-the hematology journal, 99(4), pp. 779-787. Ferrata-Storti Foundation 10.3324/haematol.2013.094151

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3f3533be799074119fee57b5831f5c

Zobrazit plný text záznamu

Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors

Autor: Peter F. Ambros, Helmut Gadner, Dave N. T. Aryee, Reinhard Windhager, Heinrich Kovar, Andreas Zoubek, Bernadette Gruber, Gunhild Jug

Publikováno v: Oncogene. 15:2225-2232

The pRB cell cycle regulatory cascade is frequently perturbed in neoplasia by overexpression of a component of the pRB-phosphorylating cyclin D1/CDK4 complex or by inactivation of pRB or the CDK4 inhibitors p16 and p15. We investigated the status and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adb192231c6727716a7eb6e31c5852c
https://doi.org/10.1038/sj.onc.1201397

Zobrazit plný text záznamu

Minimal metastatische - und minimal residuelle Erkrankung bei Patienten mit Ewing-Tumoren

Autor: Andrea Luegmayer, Michael Dworzak, Peter F. Ambros, Reinhard Windhager, Martina Kronberger, Heinrich Kovar, Christa Pfleiderer, Andreas Zoubek, E. Koscielniak, Helmut Gadner, Bernadette Gruber, Christian Urban, Franz M. Fink

Publikováno v: Klinische Pädiatrie. 207:242-247

At least 95% of Ewing tumors (ET) are characterized by an EWS-gene rearrangement with either FLI-1 or ERG and by extraordinary high MIC2/CD99 expression. Both features can be used for the specific identification of tumor cells, which might also be pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84420c9583230c9cc747c52029a54789
https://doi.org/10.1055/s-2008-1046548

Zobrazit plný text záznamu

Detection of tumour cells in peripheral blood and bone marrow from ewing tumour patients by rt-pcr

Autor: Martina Kronberger, Christa Pfleiderer, Heinrich Kovar, Bernadette Gruber, Franz-Martin Fink, Andreas Zoubek, Thomas Lion, Peter F. Ambros, Helmut Gadner

Publikováno v: International Journal of Cancer. 64:135-139

The Ewing family of tumours (ET) is characterised at the cytogenetic level by unique chromosome 22 rearrangements. The breakpoints have been cloned and were shown to fuse the EWS gene on chromosome 22 to one of two closely related ETS proto-oncogenes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24f489dc0669ddbd7d7a64bda13b810
https://doi.org/10.1002/ijc.2910640211

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání