Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bernadette A. Chua"'
Autor:
Lorena Hidalgo San Jose, Mary Jean Sunshine, Christopher H. Dillingham, Bernadette A. Chua, Miriama Kruta, Yuning Hong, Danny M. Hatters, Robert A.J. Signer
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 69-80.e6 (2020)
Summary: Low protein synthesis is a feature of somatic stem cells that promotes regeneration in multiple tissues. Modest increases in protein synthesis impair stem cell function, but the mechanisms by which this occurs are largely unknown. We determi
Externí odkaz:
https://doaj.org/article/a1e642bc95c44510b2cb20474eabe20d
Autor:
Bernadette A. Chua, Connor J. Lennan, Mary Jean Sunshine, Daniela Dreifke, Ashu Chawla, Eric J. Bennett, Robert A.J. Signer
Publikováno v:
Cell Stem Cell. 30:460-472.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86bf7c70824c4945714689d4ca489a9f
https://doi.org/10.1016/j.stem.2023.02.010
https://doi.org/10.1016/j.stem.2023.02.010
Autor:
Bernadette Anne Chua, Connor J Lennan, Mary Jean Sunshine, Ashu Chawla, Lorena H San Jose, Daniela Dreifke, Eric J Bennett, Robert Signer
Publikováno v:
Blood. 140:5723-5723
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9722080f5403fbccdeec15a425b9fe90
https://doi.org/10.1182/blood-2022-163857
https://doi.org/10.1182/blood-2022-163857
Autor:
Bernadette A. Chua, Robert A.J. Signer
Publikováno v:
Curr Opin Hematol
Current opinion in hematology, vol 27, iss 4
Current opinion in hematology, vol 27, iss 4
PURPOSE OF REVIEW: Protein homeostasis (proteostasis) is maintained by an integrated network of physiological mechanisms and stress response pathways that regulate the content and quality of the proteome. The maintenance of cellular proteostasis is k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14738cded0e250f0584eb4559fa868b3
https://europepmc.org/articles/PMC7357843/
https://europepmc.org/articles/PMC7357843/
Publikováno v:
Cell Stem Cell
Cell stem cell, vol 26, iss 2
Cell stem cell, vol 26, iss 2
Cellular identity is not driven by differences in genomic content but rather by epigenomic, transcriptomic, and proteomic heterogeneity. Although regulation of the epigenome plays a key role in shaping stem cell hierarchies, differential expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b956291a1502ebce8ec7cfcb8e2d697
https://pubmed.ncbi.nlm.nih.gov/32032524
https://pubmed.ncbi.nlm.nih.gov/32032524
Autor:
Mary Jean Sunshine, Danny M. Hatters, Lorena Hidalgo San Jose, Christopher H. Dillingham, Miriama Krutá, Robert A.J. Signer, Yuning Hong, Bernadette A. Chua
Publikováno v:
Cell reports, vol 30, iss 1
Cell Reports, Vol 30, Iss 1, Pp 69-80.e6 (2020)
Cell reports
Cell Reports, Vol 30, Iss 1, Pp 69-80.e6 (2020)
Cell reports
SUMMARY Low protein synthesis is a feature of somatic stem cells that promotes regeneration in multiple tissues. Modest increases in protein synthesis impair stem cell function, but the mechanisms by which this occurs are largely unknown. We determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d16221abeff9a14d0f9da82721588a
https://escholarship.org/uc/item/23303692
https://escholarship.org/uc/item/23303692
Autor:
Bernadette A. Chua, Christopher H. Dillingham, Mary Jean Sunshine, Fanny J. Zhou, Lorena Hidalgo San Jose, Bijou De Jong, Miriama Krutá, Yunpeng Fu, Ashu Chawla, Robert A.J. Signer
Publikováno v:
Cell Stem Cell. 28:1950-1965.e6
Summary Maintaining proteostasis is key to resisting stress and promoting healthy aging. Proteostasis is necessary to preserve stem cell function, but little is known about the mechanisms that regulate proteostasis during stress in stem cells, and wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d1ff1148f18ce7381640dc2edff19a
https://doi.org/10.1016/j.stem.2021.07.009
https://doi.org/10.1016/j.stem.2021.07.009
Publikováno v:
Cell communication and signaling : CCS, vol 17, iss 1
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-9 (2019)
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-9 (2019)
Cell Communication and Signaling : CCS
Phosphatidylserine (PtdSer) is usually present only in the inner leaf of the lipid bilayers of the cell membrane, but is exposed on the outer leaf when cells are activated and/or die. Exposure of PtdSer has physiological functions. For example, the P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97813e51a98dd113e259a70a7046843e
https://escholarship.org/uc/item/7xq2q390
https://escholarship.org/uc/item/7xq2q390
Conjugating certain types of lentiviral vectors with targeting ligands can redirect the vectors to specifically transduce desired cell types. However, extensive genetic and/or biochemical manipulations are required for conjugation, which hinders appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c83d11897b2574cf54238c1b1399a42
https://escholarship.org/uc/item/9g96d2sw
https://escholarship.org/uc/item/9g96d2sw
Autor:
Christina M. Ramirez, Kathy Situ, Bernadette A. Chua, Jamie Ann Ngo, Haruko Nakano, Kouki Morizono
Efferocytosis, the phagocytic clearance of apoptotic cells, can provide host protection against certain types of viruses by mediating phagocytic clearance of infected cells undergoing apoptosis. It is known that HIV-1 induces apoptosis and HIV-1-infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63abc6c833891548a75645ff01561603
https://escholarship.org/uc/item/0qc5g4qt
https://escholarship.org/uc/item/0qc5g4qt