Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Bernadett Bacsa"'
Publikováno v:
Cells, Vol 13, Iss 6, p 468 (2024)
Many essential biological processes are triggered by the proximity of molecules. Meanwhile, diverse approaches in synthetic biology, such as new biological parts or engineered cells, have opened up avenues to precisely control the proximity of molecu
Externí odkaz:
https://doaj.org/article/99e58ca849664aac99ea02977f43efcf
Autor:
Bernadett Bacsa, Annarita Graziani, Denis Krivic, Patrick Wiedner, Roland Malli, Thomas Rauter, Oleksandra Tiapko, Klaus Groschner
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Canonical transient receptor potential (TRPC) channels are considered as elements of the immune cell Ca2+ handling machinery. We therefore hypothesized that TRPC photopharmacology may enable uniquely specific modulation of immune responses. Utilizing
Externí odkaz:
https://doaj.org/article/221a4a492cf645c7af96cfa02cdbacfe
Autor:
Niroj Shrestha, Bernadett Bacsa, Hwei Ling Ong, Susanne Scheruebel, Helmut Bischof, Roland Malli, Indu Suresh Ambudkar, Klaus Groschner
Publikováno v:
PLoS Biology, Vol 18, Iss 4, p e3000700 (2020)
Trimeric intracellular cation (TRIC) channels have been proposed to modulate Ca2+ release from the endoplasmic reticulum (ER) and determine oscillatory Ca2+ signals. Here, we report that TRIC-A-mediated amplitude and frequency modulation of ryanodine
Externí odkaz:
https://doaj.org/article/c56f5c800b114eb09cbf5150a7c65b5e
Autor:
Annarita Graziani, Bernadett Bacsa, Denis Krivic, Patrick Wiedner, Sanja Curcic, Rainer Schindl, Oleksandra Tiapko, Klaus Groschner
Publikováno v:
Cells, Vol 9, Iss 3, p 556 (2020)
Canonical transient receptor potential (TRPC) channels were identified as key players in maladaptive remodeling, with nuclear factor of activated T-cells (NFAT) transcription factors serving as downstream targets of TRPC-triggered Ca2+ entry in these
Externí odkaz:
https://doaj.org/article/3603eee68b2e4c05bd40e4d9d98d03f1
Publikováno v:
Current Opinion in Physiology. 17:25-33
The transient receptor potential (TRP) superfamily of plasma membrane cation channels has been recognized as a signaling hub in highly diverse settings of human physiopathology. In the past three decades of TRP research, attention was focused mainly
Autor:
Denis Krivic, Bernadett Bacsa, Kathrin S. Maitz, Annarita Graziani, Julia Kargl, Klaus Groschner
Publikováno v:
Biophysical Journal. 122:256a
Publikováno v:
Current opinion in physiology
The transient receptor potential (TRP) superfamily of plasma membrane cation channels has been recognized as a signaling hub in highly diverse settings of human physiopathology. In the past three decades of TRP research, attention was focused mainly
Publikováno v:
Biophysical Journal. 121:505a
Autor:
Ferenc Zsila, Szilvia Bősze, Tamás Mlinkó, Nóra Szabó, Ferenc Hudecz, Bernadett Bacsa, Kata Horváti
Publikováno v:
Amino Acids. 49:1053-1067
Cationic peptides proved fundamental importance as pharmaceutical agents and/or drug carrier moieties functioning in cellular processes. The comparison of the in vitro activity of these peptides is an experimental challenge and a combination of diffe
Publikováno v:
Science China Life Sciences. 59:802-810
Photouncaging of second messengers has been successfully employed to gain mechanistic insight of cellular signaling pathways. One of the most enigmatic processes of ion channel regulation is lipid recognition and lipid-gating of TRPC channels, which