Comparative In Vitro Activities of First and Second-Generation Ceragenins Alone and in Combination with Antibiotics Against Multidrug-Resistant Klebsiella pneumoniae Strains

Autor: Berna Ozbek-Celik, Damla Damar-Celik, Emel Mataraci-Kara, Cagla Bozkurt-Guzel, Paul B. Savage

Publikováno v: Antibiotics, Vol 8, Iss 3, p 130 (2019)

Objectives: The ceragenins, or CSAs, were designed to mimic the activities of antimicrobial peptides and represent a new class of antimicrobial agent. The aim of this study was to comparatively investigate the antimicrobial activities of first/second

Externí odkaz: https://doaj.org/article/bd9459ced299484ca5ba34c48035a23f

Plastoquinone analogs: a potential antimicrobial lead structure intensely suppressing Staphylococcus epidermidis and Candida albicans growth

Autor: Emel Mataracı-Kara, Berna Ozbek-Celik, Mahmut Yıldız, Amaç Fatih Tuyun, Hatice Yıldırım, Merve Ataman, Nilüfer Bayrak

Publikováno v: Medicinal Chemistry Research. 30:1728-1737

The aim of this study was to evaluate the antimicrobial activity of twenty-five Plastoquinone analogs synthesized previously in a panel of seven bacterial strains (three Gram-positive and four Gram-negative bacteria) and three fungi. PQ1, which does

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56f0ee3d7f5bc4e33786d762b2720d1d
https://doi.org/10.1007/s00044-021-02772-z

Antibacterial and antibiofilm activities of ceragenins against Achromobacter species isolated from cystic fibrosis patients

Autor: Paul B. Savage, Damla Damar-Çelik, Emel Mataracı-Kara, Berna Ozbek-Celik

Publikováno v: Journal of Chemotherapy. 33:216-227

Achromobacter species, which are recognized as emerging pathogens isolated from patients with cystic fibrosis, are capable of forming biofilm in the respiratory tract in patients and innate multidr...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d358e2178272c3d06f5134de864d22ed
https://doi.org/10.1080/1120009x.2020.1819702

Comparative in vitro activities of meropenem in combination with colistin, levofloxacin, or chloramphenicol against Achromobacter xylosoxidans strains isolated from patients with cystic fibrosis

Autor: Damla Damar-Çelik, Niels Nørskov-Lauritsen, Berna Ozbek-Celik

Publikováno v: Journal of Global Antimicrobial Resistance, Vol 22, Iss, Pp 713-717 (2020)
Damar-Çelik, D, Nørskov-Lauritsen, N & Özbek-Çelik, B 2020, ' Comparative in vitro activities of meropenem in combination with colistin, levofloxacin, or chloramphenicol against Achromobacter xylosoxidans strains isolated from patients with cystic fibrosis ', Journal of Global Antimicrobial Resistance, vol. 22, pp. 713-717 . https://doi.org/10.1016/j.jgar.2020.06.001

Objectives Achromobacter xylosoxidans is an emerging pathogen in cystic fibrosis (CF). Relatively little is known about its clinical impact and optimal management. In the present study, the in vitro bactericidal activities of meropenem, either alone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855880ad7e1c8ceed1bd76d006208ef2
http://www.sciencedirect.com/science/article/pii/S2213716520301442

In Vitro Synergistic Effect and Mutant Prevention Concentrations of Cefepime Alone or in Combination with Sulbactam Against OXA-48-positive Klebsiella pneumoniae Isolates

Autor: Emel Mataracı-Kara, Berna Ozbek-Celik, Mesut Yilmaz

Publikováno v: Current Microbiology. 77:2137-2142

The aim of this study is to investigate the combination of cefepime and sulbactam. Sulbactam, when administered , will effectively inhibit all Extended-spectrum beta lactamases (ESBLs) of the microorganism, while cefepime will inhibit the growth of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed282e06b943cde641e3722398148a5f
https://doi.org/10.1007/s00284-020-02094-0