Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Berlinda Verdoodt"'
Autor:
Timm M. Reissig, Swetlana Ladigan‐Badura, Anja Steinberg, Abdelouahid Maghnouj, Ting Li, Berlinda Verdoodt, Sven T. Liffers, Michael Pohl, Heiner Wolters, Christian Teschendorf, Richard Viebahn, Jakob Admard, Nicolas Casadei, Andrea Tannapfel, Wolff Schmiegel, Stephan A. Hahn, Deepak B. Vangala
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2396-2414 (2023)
Although approximately half of all metastatic colorectal cancers (mCRCs) harbour mutations in KRAS or NRAS, hardly any progress has been made regarding targeted treatment for this group over the last few years. Here, we investigated the efficacy of v
Externí odkaz:
https://doaj.org/article/43b89c56d838488bb188749e4ab6758c
Liquid biopsy based HER2 amplification status in gastric cancer patients indicates clinical response
Autor:
Susanne Klein-Scory, Swetlana Ladigan-Badura, Thomas Mika, Berlinda Verdoodt, Andrea Tannapfel, Michael Pohl, Roland Schroers, Alexander Baraniskin
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21339- (2023)
Gastric carcinomas are among the most common cancers in Germany, with approximately 18,000 new cases per year.About 10 years ago, based on results of the Trastuzumab for gastric cancer (ToGA) trial, the addition of the monoclonal antibody trastuzumab
Externí odkaz:
https://doaj.org/article/3a8d470018564dc88e905b8ceaebec60
Autor:
Deepak Vangala, Swetlana Ladigan, Sven T. Liffers, Soha Noseir, Abdelouahid Maghnouj, Tina-Maria Götze, Berlinda Verdoodt, Susanne Klein-Scory, Laura Godfrey, Martina K. Zowada, Mario Huerta, Daniel L. Edelstein, Jaime Martinez de Villarreal, Miriam Marqués, Jörg Kumbrink, Andreas Jung, Tobias Schiergens, Jens Werner, Volker Heinemann, Sebastian Stintzing, Doris Lindoerfer, Ulrich Mansmann, Michael Pohl, Christian Teschendorf, Christiane Bernhardt, Heiner Wolters, Josef Stern, Selami Usta, Richard Viebahn, Jacob Admard, Nicolas Casadei, Stefan Fröhling, Claudia R. Ball, Jens T. Siveke, Hanno Glimm, Andrea Tannapfel, Wolff Schmiegel, Stephan A. Hahn
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-25 (2021)
Abstract Background The development of secondary resistance (SR) in metastatic colorectal cancer (mCRC) treated with anti-epidermal growth factor receptor (anti-EGFR) antibodies is not fully understood at the molecular level. Here we tested in vivo s
Externí odkaz:
https://doaj.org/article/cfb1d471a175414a977bd791dd7bb74a
Autor:
Berlinda Verdoodt, Markus Vogt, Inge Schmitz, Sven-Thorsten Liffers, Andrea Tannapfel, Alireza Mirmohammadsadegh
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44132 (2012)
BACKGROUND: Salinomycin is a polyether ionophore antibiotic that has recently been shown to induce cell death in human cancer cells displaying multiple mechanisms of drug resistance. The underlying mechanisms leading to cell death after salinomycin t
Externí odkaz:
https://doaj.org/article/0dc59b5162884c95a1f36cb7e3775f83
Autor:
Guillaume Normand, Philipp G. Hemmati, Berlinda Verdoodt, Clarissa von Haefen, Jana Wendt, Dilek Güner, Evelyne May, Bernd Dörken, Peter T. Daniel
Publikováno v:
J Biol Chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0824d511bc01d89f0b5a6e8d351bca8f
https://europepmc.org/articles/PMC10124944/
https://europepmc.org/articles/PMC10124944/
Autor:
Andrea Tannapfel, Larissa Kluxen, Hendrik Juette, Christian Teschendorf, Berlinda Verdoodt, Stefanie Noepel-Duennebacke, Lars Engel, Anke Reinacher-Schick, Guido Trenn, Inke Sabine Feder, Metin Senkal, Heiner Wolters, Torsten Herzog, Waldemar Uhl, Lothar Mueller, Renate Klaassen-Mielke, Nadezda Basara, W. F. A. Hiller
Publikováno v:
Zeitschrift fur Gastroenterologie. 58(6)
Colorectal cancer is one of the leading malignancies and still accounts for almost 25 000 deaths in Germany each year. Although there is accumulating data on the molecular basis, treatment and clinical outcome of patients within clinical trials evide
Publikováno v:
Oncotarget
The p53-inducible cell cycle regulator 14-3-3σ exhibits tumor suppressive functions and is highly expressed in differentiating layers of the epidermis and hair follicles. 14-3-3σ/SFN/stratifin is frequently silenced in human epithelial cancers, and
Autor:
Sven-Thorsten Liffers, Berlinda Verdoodt, Markus Vogt, Andrea Tannapfel, Joachim Noldus, Viktoria Kuhn, Matthias Neid, Alireza Mirmohammadsadegh, Rein-Jüri Palisaar
Publikováno v:
International Journal of Oncology. 43:307-314
Decreased expression of the microRNA miR-205 has been observed in multiple tumour types due to its role in the epithelial to mesenchymal transition, which promotes metastasis. We determined the expression of miR-205 in 111 archival samples of prostat
Autor:
Stephan A. Hahn, Alireza Mirmohammadsadegh, Sven-T Liffers, Sandeep Nambiar, Berlinda Verdoodt, Abdelouahid Maghnouj, Andrea Tannapfel, Johanna Munding, Jan Dominik Kuhlmann, Markus Vogt
Publikováno v:
Laboratory Investigation. 91:1472-1479
MicroRNAs (miRNAs: short non-coding RNAs) are emerging as a class of potential novel tumor markers, as their dysregulation is being increasingly reported in various types of cancers. In the present study, we investigated the transcription status of m
Autor:
Andrea Tannapfel, Sandeep Nambiar, Berlinda Verdoodt, Matthias Neid, Joachim Noldus, Rein-Jüri Palisaar, Markus Vogt, Alireza Mirmohammadsadegh, Florian Sommerer
Publikováno v:
Prostate Cancer and Prostatic Diseases. 14:295-301
Promoter hypermethylation is an important epigenetic mechanism in the regulation of several key modulators of prostate carcinoma progression. Recent studies suggest that the polycomb-group (PcG) protein BMI1 may have an impact on epigenetic regulatio