Local immune cell contributions to fracture healing in aged individuals - A novel role for interleukin 22.

Autor: Bucher CH; Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Augustenburger Platz 1, 13353, Germany.; BIH Center for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Berlin-Brandenburg School for Regenerative Therapies, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany., Berkmann JC; Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Augustenburger Platz 1, 13353, Germany.; BIH Center for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Berlin-Brandenburg School for Regenerative Therapies, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany., Burkhardt LM; Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Augustenburger Platz 1, 13353, Germany.; Berlin-Brandenburg School for Regenerative Therapies, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany., Paschke C; Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Augustenburger Platz 1, 13353, Germany.; BIH Center for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Berlin-Brandenburg School for Regenerative Therapies, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany., Schlundt C; Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Augustenburger Platz 1, 13353, Germany.; BIH Center for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany., Lang A; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, Charitéplatz 1, 10117, Berlin, Germany., Wolter A; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, Charitéplatz 1, 10117, Berlin, Germany., Damerau A; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, Charitéplatz 1, 10117, Berlin, Germany., Geissler S; Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Augustenburger Platz 1, 13353, Germany.; BIH Center for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany., Volk HD; BIH Center for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany., Duda GN; Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Augustenburger Platz 1, 13353, Germany.; BIH Center for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany., Schmidt-Bleek K; Julius Wolff Institute of Biomechanics and Musculoskeletal Regeneration, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Augustenburger Platz 1, 13353, Germany. katharina.schmidt-bleek@charite.de.; BIH Center for Regenerative Therapies, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany. katharina.schmidt-bleek@charite.de.

Publikováno v: Experimental & molecular medicine [Exp Mol Med] 2022 Aug; Vol. 54 (8), pp. 1262-1276. Date of Electronic Publication: 2022 Aug 26.

Hybrid Injectable Sol-Gel Systems Based on Thermo-Sensitive Polyurethane Hydrogels Carrying pH-Sensitive Mesoporous Silica Nanoparticles for the Controlled and Triggered Release of Therapeutic Agents.

Autor: Boffito M; Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy., Torchio A; Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.; Department of Surgical Sciences, Università degli Studi di Torino, Turin, Italy., Tonda-Turo C; Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy., Laurano R; Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.; Department of Surgical Sciences, Università degli Studi di Torino, Turin, Italy., Gisbert-Garzarán M; Departamento de Química en Ciencias Farmacéuticas, Instituto de Investigación Sanitaria del Hospital, Universidad Complutense de Madrid, Madrid, Spain.; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain., Berkmann JC; Julius Wolff Institut, Charité - Universitätsmedizin Berlin, Berlin, Germany., Cassino C; Department of Science and Technological Innovation, Università del Piemonte Orientale, Alessandria, Italy., Manzano M; Departamento de Química en Ciencias Farmacéuticas, Instituto de Investigación Sanitaria del Hospital, Universidad Complutense de Madrid, Madrid, Spain.; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain., Duda GN; Julius Wolff Institut, Charité - Universitätsmedizin Berlin, Berlin, Germany.; BIH Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Berlin, Germany., Vallet-Regí M; Departamento de Química en Ciencias Farmacéuticas, Instituto de Investigación Sanitaria del Hospital, Universidad Complutense de Madrid, Madrid, Spain.; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain., Schmidt-Bleek K; Julius Wolff Institut, Charité - Universitätsmedizin Berlin, Berlin, Germany.; BIH Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Berlin, Germany., Ciardelli G; Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.

Publikováno v: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2020 May 19; Vol. 8, pp. 384. Date of Electronic Publication: 2020 May 19 (Print Publication: 2020).

Engineered pH-Responsive Mesoporous Carbon Nanoparticles for Drug Delivery.

Autor: Gisbert-Garzarán M; Department of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain., Berkmann JC; Julius Wolff Institute and Center for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Berlin-Brandenburg School for Regenerative Therapies, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Giasafaki D; National Center for Scientific Research 'Demokritos', Agia Paraskevi Attikis, 15341 Athens, Greece., Lozano D; Department of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain., Spyrou K; Department of Materials Science and Engineering, University of Ioannina, GR-45110 Ioannina, Greece., Manzano M; Department of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain., Steriotis T; National Center for Scientific Research 'Demokritos', Agia Paraskevi Attikis, 15341 Athens, Greece., Duda GN; Julius Wolff Institute and Center for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Berlin-Brandenburg School for Regenerative Therapies, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Berlin Institute of Health Center for Regenerative Therapies, 13353 Berlin, Germany., Schmidt-Bleek K; Julius Wolff Institute and Center for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; Berlin-Brandenburg School for Regenerative Therapies, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Charalambopoulou G; National Center for Scientific Research 'Demokritos', Agia Paraskevi Attikis, 15341 Athens, Greece., Vallet-Regí M; Department of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.

Publikováno v: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2020 Apr 01; Vol. 12 (13), pp. 14946-14957. Date of Electronic Publication: 2020 Mar 17.

Milk Fat Globule Membrane Supplementation in Formula Modulates the Neonatal Gut Microbiome and Normalizes Intestinal Development.

Autor: Bhinder G; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Allaire JM; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Garcia C; Nutrition and Metabolism Research Program, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Lau JT; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Chan JM; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Ryz NR; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Bosman ES; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Graef FA; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Crowley SM; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Celiberto LS; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Berkmann JC; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Dyer RA; Nutrition and Metabolism Research Program, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Jacobson K; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Surette MG; Department of Medicine, McMaster University, Hamilton, ON, Canada., Innis SM; Nutrition and Metabolism Research Program, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada., Vallance BA; Division of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC, Canada.

Publikováno v: Scientific reports [Sci Rep] 2017 Mar 28; Vol. 7, pp. 45274. Date of Electronic Publication: 2017 Mar 28.

The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations.

Autor: Diederichs S; Division of Cancer Research, Department of Thoracic Surgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany Division of RNA Biology & Cancer (B150), German Cancer Research Center (DKFZ), Heidelberg, Germany German Cancer Consortium (DKTK), Freiburg, Germany s.diederichs@dkfz.de., Bartsch L; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Berkmann JC; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Fröse K; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Heitmann J; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Hoppe C; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Iggena D; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Jazmati D; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Karschnia P; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Linsenmeier M; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Maulhardt T; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Möhrmann L; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Morstein J; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Paffenholz SV; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Röpenack P; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Rückert T; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Sandig L; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Schell M; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Steinmann A; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Voss G; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Wasmuth J; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Weinberger ME; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany., Wullenkord R; German Academic Scholarship Foundation - Studienstiftung des deutschen Volkes, Bonn, Germany.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2016 May 02; Vol. 8 (5), pp. 442-57. Date of Electronic Publication: 2016 May 02 (Print Publication: 2016).