0A07-01. HIV-specific CD8+ T-cells of vaccinees exhibit proliferative and cytotoxic capacities comparable to those of progressors

Autor: McElrath J, Duerr A, Joshi RP, Compton AA, Berkley AM, Migueles SA, Rood JE, Connors M

Publikováno v: Retrovirology, Vol 6, Iss Suppl 3, p O49 (2009)

Externí odkaz: https://doaj.org/article/b88083cae3cd4729bcdd105de4aa70ac

High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies.

Autor: Lombana TN; a Department of Antibody Engineering , Genentech Inc ., South San Francisco , USA., Matsumoto ML; b Structural Biology , Genentech Inc ., South San Francisco , USA., Berkley AM; c Translational Oncology , Genentech Inc ., South San Francisco , USA., Toy E; c Translational Oncology , Genentech Inc ., South San Francisco , USA., Cook R; d Biochemical and Cellular Pharmacology , Genentech Inc ., South San Francisco , USA., Gan Y; e Microchemistry, Proteomics and Lipidomics , Genentech Inc ., South San Francisco , USA., Du C; d Biochemical and Cellular Pharmacology , Genentech Inc ., South San Francisco , USA., Schnier P; e Microchemistry, Proteomics and Lipidomics , Genentech Inc ., South San Francisco , USA., Sandoval W; e Microchemistry, Proteomics and Lipidomics , Genentech Inc ., South San Francisco , USA., Ye Z; d Biochemical and Cellular Pharmacology , Genentech Inc ., South San Francisco , USA., Schartner JM; c Translational Oncology , Genentech Inc ., South San Francisco , USA., Kim J; f Cancer Immunology , Genentech Inc ., South San Francisco , USA., Spiess C; a Department of Antibody Engineering , Genentech Inc ., South San Francisco , USA.

Publikováno v: MAbs [MAbs] 2019 Jan; Vol. 11 (1), pp. 75-93. Date of Electronic Publication: 2018 Nov 22.

Cutting edge: CD8+ recent thymic emigrants exhibit increased responses to low-affinity ligands and improved access to peripheral sites of inflammation.

Autor: Berkley AM; Department of Immunology, University of Washington, Seattle, WA 98109., Fink PJ; Department of Immunology, University of Washington, Seattle, WA 98109 pfink@uw.edu.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2014 Oct 01; Vol. 193 (7), pp. 3262-6. Date of Electronic Publication: 2014 Aug 29.

Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner.

Autor: Chu T; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Tyznik AJ, Roepke S, Berkley AM, Woodward-Davis A, Pattacini L, Bevan MJ, Zehn D, Prlic M

Publikováno v: Cell reports [Cell Rep] 2013 Mar 28; Vol. 3 (3), pp. 701-8. Date of Electronic Publication: 2013 Mar 21.

Defective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy.

Autor: Migueles SA; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-1876, USA., Weeks KA, Nou E, Berkley AM, Rood JE, Osborne CM, Hallahan CW, Cogliano-Shutta NA, Metcalf JA, McLaughlin M, Kwan R, Mican JM, Davey RT Jr, Connors M

Publikováno v: Journal of virology [J Virol] 2009 Nov; Vol. 83 (22), pp. 11876-89. Date of Electronic Publication: 2009 Sep 02.