Zobrazeno 1 - 10
of 9 515
pro vyhledávání: '"Berkley"'
Photorespiratory glycine contributes to photosynthetic induction during low to high light transition
Autor:
Xinyu Fu, Berkley J. Walker
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Leaves experience near-constant light fluctuations daily. Past studies have identified many limiting factors of slow photosynthetic induction when leaves transition from low light to high light. However, the contribution of photorespiration
Externí odkaz:
https://doaj.org/article/132f6a3772d54035826d46a91bde719d
Autor:
Andrew T. Willis, Anna R. Dahlgren, Kevin D. Woolard, Sharmila Ghosh, Callum G. Donnelly, Andres de laConcha‐Bermejillo, Ana Pacheco, Katherine D. Watson, Emily Berryhill, Monica Aleman, Fiona Wensley, Sarah Humphreys, Ashley E. Whitehead, Dayna Goldsmith, Berkley Chesen, John Ragsdale, James E. Tompkins, Ron Nash, Amanda H. Plunkett, Heath J. Qualls, Katarina Rodriguez, Damaris Hochanadel, Andrew D. Miller, Carrie J. Finno
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1808-1814 (2024)
Abstract Background In 2020, a novel neurologic disease was observed in juvenile Quarter Horses (QHs) in North America. It was unknown if this was an aberrant manifestation of another previously described neurological disorder in foals, such as equin
Externí odkaz:
https://doaj.org/article/179656e52ca543f49e7aad35f72282c6
Autor:
Deblina Banerjee, Sukriti Bagchi, Zhihui Liu, Hsien-Chao Chou, Man Xu, Ming Sun, Sara Aloisi, Zalman Vaksman, Sharon J. Diskin, Mark Zimmerman, Javed Khan, Berkley Gryder, Carol J. Thiele
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Temporal regulation of super-enhancer (SE) driven transcription factors (TFs) underlies normal developmental programs. Neuroblastoma (NB) arises from an inability of sympathoadrenal progenitors to exit a self-renewal program and terminally d
Externí odkaz:
https://doaj.org/article/e046b0fa15084801bf258b679fd00713
Autor:
Yong Yean Kim, Berkley E. Gryder, Ranuka Sinniah, Megan L. Peach, Jack F. Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M. Woldemichael, Benjamin Z. Stanton, David Milewski, Joseph J. Barchi, John S. Schneekloth, Raj Chari, Joshua T. Kowalczyk, Shilpa R. Shenoy, Jason R. Evans, Young K. Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O’Neill, Lisa M. Jenkins, Nadya I. Tarasova, Jun S. Wei, James B. McMahon, Barry R. O’Keefe, Robert G. Hawley, Javed Khan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Fusion-positive rhabdomyosarcoma (FP-RMS) is an aggressive pediatric sarcoma driven primarily by the PAX3-FOXO1 fusion oncogene, for which therapies targeting PAX3-FOXO1 are lacking. Here, we screen 62,643 compounds using an engineered cell
Externí odkaz:
https://doaj.org/article/62fcc583cb83489ca474d4e078b73633
Autor:
Silvia Pomella, Matteo Cassandri, Lucrezia D’Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S. Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R. Vakoc, Enrico Velardi, Beat W. Schafer, Ernesto Guccione, Susanne A. Gatz, Ajla Wasti, Marielle Yohe, Myron Ignatius, Concetta Quintarelli, Janet Shipley, Lucio Miele, Javed Khan, Peter J. Houghton, Francesco Marampon, Berkley E. Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Rhabdomyosarcomas (RMS) are pediatric mesenchymal-derived malignancies encompassing PAX3/7-FOXO1 Fusion Positive (FP)-RMS, and Fusion Negative (FN)-RMS with frequent RAS pathway mutations. RMS express the master myogenic transcription factor
Externí odkaz:
https://doaj.org/article/b02d638fdabc4c31acb1630b1acf4c96
Autor:
Yaw Asante, Katharina Benischke, Issra Osman, Quy A. Ngo, Jakob Wurth, Dominik Laubscher, Hyunmin Kim, Bhavatharini Udhayakumar, Md Imdadul H. Khan, Diana H. Chin, Jadon Porch, Maharshi Chakraborty, Richard Sallari, Olivier Delattre, Sakina Zaidi, Sarah Morice, Didier Surdez, Sara G. Danielli, Beat W. Schäfer, Berkley E. Gryder, Marco Wachtel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Activation of oncogenic gene expression from long-range enhancers is initiated by the assembly of DNA-binding transcription factors (TF), leading to recruitment of co-activators such as CBP/p300 to modify the local genomic context and facili
Externí odkaz:
https://doaj.org/article/8b11c89f44b84a3f89f0cbe46cf89665
Autor:
Thekla von Bismarck, Philipp Wendering, Leonardo Perez de Souza, Jeremy Ruß, Linnéa Strandberg, Elmien Heyneke, Berkley J. Walker, Mark A. Schöttler, Alisdair R. Fernie, Zoran Nikoloski, Ute Armbruster
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Photorespiration (PR) is the pathway that detoxifies the product of the oxygenation reaction of Rubisco. It has been hypothesized that in dynamic light environments, PR provides a photoprotective function. To test this hypothesis, we charact
Externí odkaz:
https://doaj.org/article/f0ac702f0604479da00fd2fea503e881
Autor:
W. Dean Pontius, Ellen S. Hong, Zachary J. Faber, Jeremy Gray, Craig D. Peacock, Ian Bayles, Katreya Lovrenert, Diana H. Chin, Berkley E. Gryder, Cynthia F. Bartels, Peter C. Scacheri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The metastasis-invasion cascade describes the series of steps required for a cancer cell to successfully spread from its primary tumor and ultimately grow within a secondary organ. Despite metastasis being a dynamic, multistep process, most
Externí odkaz:
https://doaj.org/article/6bb55550fb1640888f084ae083dc4872
Publikováno v:
GCB Bioenergy, Vol 15, Iss 11, Pp 1329-1338 (2023)
Abstract A long‐standing question in perennial grass breeding and physiology is whether yield improvement strategies could compromise winter survival. Since perennial grasses rely on stored carbohydrates for winter maintenance and spring regrowth,
Externí odkaz:
https://doaj.org/article/46f03eaf2c2e4c68b84dbce9dd32d48e
Autor:
Emma J. Chory, Meng Wang, Michele Ceribelli, Aleksandra M Michalowska, Stefan Golas, Erin Beck, Carleen Klumpp-Thomas, Lu Chen, Crystal McKnight, Zina Itkin, Kelli M. Wilson, David Holland, Sanjay Divakaran, James Bradner, Javed Khan, Berkley E. Gryder, Craig J. Thomas, Benjamin Z. Stanton
Publikováno v:
SLAS Discovery, Vol 28, Iss 4, Pp 193-201 (2023)
ABSTRACT: We report a comprehensive drug synergy study in acute myeloid leukemia (AML). In this work, we investigate a panel of cell lines spanning both MLL-rearranged and non-rearranged subtypes. The work comprises a resource for the community, with
Externí odkaz:
https://doaj.org/article/666943293cc94a44bc30dbda4865e32e