Cytotoxicity of Doxorubicin-Curcumin Nanoparticles Conjugated with Two Different Peptides (CKR and EVQ) against FLT3 Protein in Leukemic Stem Cells.

Autor: Chueahongthong F; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.; Department of Medical Technology, School of Allied Health Sciences, University of Phayao, Phayao 56000, Thailand., Chiampanichayakul S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.; Center of Excellence in Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.; Cancer Research Unit of Associated Medical Sciences (AMS-CRU), Chiang Mai University, Chiang Mai 50200, Thailand., Viriyaadhammaa N; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.; Cancer Research Unit of Associated Medical Sciences (AMS-CRU), Chiang Mai University, Chiang Mai 50200, Thailand., Dejkriengkraikul P; Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand., Okonogi S; Center of Excellence in Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand., Berkland C; Department of Biomedical Engineering and Department of Chemistry, Washington University in St. Louis, Saint Louis, MO 63105, USA., Anuchapreeda S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.; Center of Excellence in Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.; Cancer Research Unit of Associated Medical Sciences (AMS-CRU), Chiang Mai University, Chiang Mai 50200, Thailand.

Publikováno v: Polymers [Polymers (Basel)] 2024 Sep 02; Vol. 16 (17). Date of Electronic Publication: 2024 Sep 02.

Soluble antigen arrays provide increased efficacy and safety over free peptides for tolerogenic immunotherapy.

Autor: Firdessa-Fite R; Columbia Center for Translational Immunology, Department of Medicine and Naomi Berrie Diabetes Center, Columbia University Irving Medical Center, New York, NY, United States., Johnson SN; Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States., Bechi Genzano C; Columbia Center for Translational Immunology, Department of Medicine and Naomi Berrie Diabetes Center, Columbia University Irving Medical Center, New York, NY, United States., Leon MA; Department of Chemistry, University of Kansas, Lawrence, KS, United States., Ku A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center and New York Presbyterian Hospital, New York, NY, United States., Ocampo Gonzalez FA; Department of Pathology and Cell Biology, Columbia University Irving Medical Center and New York Presbyterian Hospital, New York, NY, United States., Milner JD; Department of Pediatrics, Division of Allergy and Immunology, Columbia University Irving Medical Center, New York, NY, United States., Sestak JO; Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States., Berkland C; Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.; Department of Chemical and Petroleum Engineering, University of Kansas, Lawrence, KS, United States., Creusot RJ; Columbia Center for Translational Immunology, Department of Medicine and Naomi Berrie Diabetes Center, Columbia University Irving Medical Center, New York, NY, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Jun 12; Vol. 15, pp. 1258369. Date of Electronic Publication: 2024 Jun 12 (Print Publication: 2024).

Dynamic control of contractile resistance to iPSC-derived micro-heart muscle arrays.

Autor: Schuftan D; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, Missouri, USA., Kooh YKG; Institute of Materials Science & Engineering, Washington University in St. Louis, St. Louis, Missouri, USA., Guo J; Department of Mechanical Engineering & Materials Science, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, Missouri, USA., Sun Y; Institute of Materials Science & Engineering, Washington University in St. Louis, St. Louis, Missouri, USA., Aryan L; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, Missouri, USA., Stottlemire B; Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, University of Kansas, Lawrence, Kansas, USA., Berkland C; Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, University of Kansas, Lawrence, Kansas, USA.; Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas, USA., Genin GM; Department of Mechanical Engineering & Materials Science, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.; NSF Center for Engineering Mechanobiology, St. Louis, Missouri, USA., Huebsch N; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.; NSF Center for Engineering Mechanobiology, St. Louis, Missouri, USA.

Publikováno v: Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2024 Apr; Vol. 112 (4), pp. 534-548. Date of Electronic Publication: 2023 Nov 12.

Soluble antigen arrays improve the efficacy and safety of peptide-based tolerogenic immunotherapy.

Autor: Firdessa-Fite R; Columbia Center for Translational Immunology, Department of Medicine and Naomi Berrie Diabetes Center, Columbia University Medical Center, 650 West 168 St, New York, NY 10032., Johnson SN; Department of Pharmaceutical Chemistry, University of Kansas, 2095 Constant Avenue, Lawrence, KS 66047., Leon MA; Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS 66045., Sestak JO; Department of Pharmaceutical Chemistry, University of Kansas, 2095 Constant Avenue, Lawrence, KS 66047., Berkland C; Department of Pharmaceutical Chemistry, University of Kansas, 2095 Constant Avenue, Lawrence, KS 66047.; Department of Chemical and Petroleum Engineering, University of Kansas,1530 West 15 Street, Lawrence, KS 66045., Creusot RJ; Columbia Center for Translational Immunology, Department of Medicine and Naomi Berrie Diabetes Center, Columbia University Medical Center, 650 West 168 St, New York, NY 10032.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 07. Date of Electronic Publication: 2023 May 07.

Doxorubicin-Loaded Polymeric Micelles Conjugated with CKR- and EVQ-FLT3 Peptides for Cytotoxicity in Leukemic Stem Cells.

Autor: Chueahongthong F; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand., Tima S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.; Research Center of Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.; Cancer Research Unit of Associated Medical Sciences (AMS-CRU), Chiang Mai University, Chiang Mai 50200, Thailand., Chiampanichayakul S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.; Research Center of Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.; Cancer Research Unit of Associated Medical Sciences (AMS-CRU), Chiang Mai University, Chiang Mai 50200, Thailand., Dejkriengkraikul P; Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand., Okonogi S; Research Center of Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand., Sasarom M; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand., Rodwattanagul S; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand., Berkland C; Department of Pharmaceutical Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS 66047, USA., Anuchapreeda S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.; Research Center of Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.; Cancer Research Unit of Associated Medical Sciences (AMS-CRU), Chiang Mai University, Chiang Mai 50200, Thailand.

Publikováno v: Pharmaceutics [Pharmaceutics] 2022 Oct 04; Vol. 14 (10). Date of Electronic Publication: 2022 Oct 04.