Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis

Autor: Segers, F.M.E., Ruder, A.V., Westra, M.M., Lammers, T., Dadfar, S.M., Roemhild, K., Lam, T.S., Kooi, M.E., Cleutjens, K.B.J.M., Verheyen, F.K., Schurink, G.W.H., Haenen, G.W.H., Berkel, T.J.C. van, Bot, I., Halvorsen, B., Sluimer, J.C., Biessen, E.A.L.

Publikováno v: Cardiovascular Research, 3346-3359. Oxford University Press
STARTPAGE=3346;ENDPAGE=3359;ISSN=0008-6363;TITLE=Cardiovascular Research
Cardiovascular research 118(17), 3346-3359 (2023). doi:10.1093/cvr/cvac032
Cardiovascular Research. OXFORD UNIV PRESS
Cardiovascular Research

Cardiovascular research 118(17), 3346-3359 (2023). doi:10.1093/cvr/cvac032
Published by Oxford University Press, Oxford

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129ce0f9209484192f2d33cf9afe2c8c
https://doi.org/10.1093/cvr/cvac032

Adrenalectomy stimulates the formation of initial atherosclerotic lesions: reversal by adrenal transplantation

Autor: Sluis, R.J. van der, Puijvelde, G.H.M. van, Berkel, T.J.C. van, Hoekstra, M.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______202::7f0139f8f0fd284017c2b1590c4f0720
https://hdl.handle.net/1887/45107

Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism

Autor: Karuna, R., Holleboom, A.G., Motazacker, M.M., Kuivenhoven, J.A., Frikke-Schmidt, R., Tybjaerg-Hansen, A., Georgopoulos, S., Eck, M. van, Berkel, T.J.C. van, Eckardstein, A. von der, Rentsch, K.M., Eckardstein, A. von

Publikováno v: Atherosclerosis, 214(2), 448-455
Atherosclerosis, 214(2), 448-455. Elsevier Ireland Ltd
Atherosclerosis

Secretion of 27-hydroxycholesterol (27OHC) from macrophages is considered as an alternative to HDL-mediated reverse transport of excess cholesterol. We investigated 27OHC-concentrations in plasma of humans and mice with monogenic disorders of HDL met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2f32a5d6e1e5d2f84bc22756e318cc
https://www.sciencedirect.com/science/article/pii/S0021915010008968?via=ihub

Systemic MCP1/CCR2 blockade and leukocyte specific MCP1/CCR2 inhibition affect aortic aneurysm formation differently

Autor: Waard, V. de, Bot, I., Jager, S.C.A. de, Talib, S., Egashira, K., Vries, M.R. de, Quax, P.H.A., Biessen, E.A.L., Berkel, T.J.C. van

Publikováno v: Atherosclerosis, 211(1), 84-89

Objective: CCR2, the receptor for monocyte chemoattractant protein 1 (MCP1), is involved in atherosclerosis and abdominal aortic aneurysms (AAAs). Here, we explored the potential beneficial blockade of the MCP1/CCR2 pathway. Methods: We applied an AA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3c8cfafdaa66307d8a0d77b28646b09f
https://hdl.handle.net/1887/109609

Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice

Autor: Eefting, D., Bot, I., Vries, M.R. de, Schepers, A., Bockel, J.H. van, Berkel, T.J.C. van, Biessen, E.A.L., Quax, P.H.A.

Publikováno v: Journal of Vascular Surgery, 1, 50, 152-160

Objective: Inflammatory responses to vascular injury are key events in vein graft disease and accelerated atherosclerosis, which may result in bypass failure. The monocyte chemoattractant protein-1 (MCP-1)/CC-chemokine receptor (CCR)-2 pathway is hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d00ae443e9390ce6effe86a8276e170a
http://resolver.tudelft.nl/uuid:f8bfa166-7aa9-420e-bdc5-66cb2d1d4c0b