Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Berit Packert, Jensen"'
Autor:
Christopher M. Florkowski, Peter M. George, Ottiniel Chavani, Berit Packert Jensen, R. Matthew Strother
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 142:125-135
The plasma 5,6-dihydrouracil/uracil (UH2/U) ratio is a possible phenotypic marker of dihydropyrimidine dehydrogenase (DPD) activity, hence an index of 5-fluorouracil (5-FU) response and toxicity. Studies have re-affirmed the value of 5-FU and 5,6-dih
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb6f8b1d9b27fdcb63dd940c74e68c6
https://doi.org/10.1016/j.jpba.2017.04.055
https://doi.org/10.1016/j.jpba.2017.04.055
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 138
Carboplatin is a chemotherapy drug used in a variety of cancers with the primary toxicity being exposure-dependant myelosuppression. We present the development and validation of a simple, robust inductively coupled plasma mass spectrometry (ICP-MS) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3365bc379f61c918a6ebb348f25b6b8
https://pubmed.ncbi.nlm.nih.gov/28260690
https://pubmed.ncbi.nlm.nih.gov/28260690
Publikováno v:
J. Anal. At. Spectrom.. 20:204-209
3 H-Bromohexine was dosed to rats as a model compound to allow comparison of HPLC-ICP-MS detection on bromine to radiochemical detection in an in vivo drug metabolism study. Metabolite profiles were obtained in urine and faeces extracts. No influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e7044535b1edb2d54e3007c4c77455f
https://doi.org/10.1039/b415003a
https://doi.org/10.1039/b415003a
Publikováno v:
British journal of clinical pharmacology. 74(5)
Hepatic drug clearance is thought to be reduced with age. However for highly protein bound drugs, which are cleared by capacity-limited metabolism, studies on total clearance have been conflicting. The hypothesis that protein binding decreases with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91358a3c4db21ded92c87d84462f46bc
https://pubmed.ncbi.nlm.nih.gov/22380743
https://pubmed.ncbi.nlm.nih.gov/22380743
Autor:
Berit Packert, Jensen, Rebecca Lee, Roberts, Ritva, Vyas, Gitte, Bonke, David L, Jardine, Evan James, Begg
Publikováno v:
British journal of clinical pharmacology. 73(4)
A single nucleotide polymorphism in ABCB1, which encodes P-glycoprotein, has retrospectively been associated with symptoms of nortriptyline-induced postural hypotension in depressed patients. This finding needs to be replicated in independent studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6328b99b671a84a9d6b0a24683e6a635
https://pubmed.ncbi.nlm.nih.gov/21999196
https://pubmed.ncbi.nlm.nih.gov/21999196
Autor:
Jeremy K. Nicholson, Christopher J. Smith, Ian D. Wilson, Christopher Bailey, Berit Packert Jensen, C. Rodgers
Publikováno v:
Rapid communications in mass spectrometry : RCM. 19(4)
Inductively coupled plasma mass spectrometry (ICPMS) has been used to determine the rate and routes of excretion of bromine following the intraperitoneal administration (50 mg kg−1) of 2-, 3- and 4-bromobenzoic acids to male bile-duct-cannulated ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e714951fe81069962a751482eec125a0
https://pubmed.ncbi.nlm.nih.gov/15666316
https://pubmed.ncbi.nlm.nih.gov/15666316
Autor:
Berit Packert, Jensen, Christopher J, Smith, Christopher, Bailey, Colin, Rodgers, Ian D, Wilson, Jeremy K, Nicholson
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 809(2)
ICP-MS, HPLC-ICP-MS and HPLC-ICP-MS/ESI-MS have been applied to determine the disposition and metabolic fate of 2-, 3- and 4-iodobenzoic acids following intraperitoneal administration at 50 mg kg(-1) to male bile duct cannulated rats. Quantitative ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::535699d19cacf7c543ff4e52a499fcdc
https://pubmed.ncbi.nlm.nih.gov/15315777
https://pubmed.ncbi.nlm.nih.gov/15315777
Publikováno v:
Journal of Analytical Atomic Spectrometry. 18:891
With the purpose of finding ways to combine micro-bore reversed phase HPLC with ICP-MS detection for analysis of drug substances containing chlorine, bromine and iodine, the suitability of a direct injection nebulizer and an Aridus desolvating microc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a98715aee68feb5f105c57c8ac106f6
https://doi.org/10.1039/b304651f
https://doi.org/10.1039/b304651f
Publikováno v:
JAAS (Journal of Analytical Atomic Spectrometry); Feb2007, Vol. 22 Issue 3, p235-249, 15p
Publikováno v:
JAAS (Journal of Analytical Atomic Spectrometry); Feb2005, Vol. 20 Issue 3, p204-209, 6p