Výsledky vyhledávání - "Berit Aydin-Schmidt"

Akademický článek

Surveillance of genetic markers associated with Plasmodium falciparum resistance to artemisinin-based combination therapy in Pakistan, 2018–2019

Autor: Abdul Qader Khan, Leyre Pernaute-Lau, Aamer Ali Khattak, Sanna Luijcx, Berit Aydin-Schmidt, Mubashir Hussain, Taj Ali Khan, Farees Uddin Mufti, Ulrika Morris

Publikováno v: Malaria Journal, Vol 19, Iss 1, Pp 1-9 (2020)

Abstract Background The spread of artemisinin resistance in the Greater Mekong Subregion of Southeast Asia poses a significant threat for current anti-malarial treatment guidelines globally. The aim of this study was to assess the current prevalence

Externí odkaz: https://doaj.org/article/9f457b3cb3c540f8ae540cce07f1a785

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Akademický článek

A cluster randomised controlled trial of two rounds of mass drug administration in Zanzibar, a malaria pre-elimination setting—high coverage and safety, but no significant impact on transmission

Autor: Ulrika Morris, Mwinyi I. Msellem, Humphrey Mkali, Atiqul Islam, Berit Aydin-Schmidt, Irina Jovel, Shija Joseph Shija, Mwinyi Khamis, Safia Mohammed Ali, Lamija Hodzic, Ellinor Magnusson, Eugenie Poirot, Adam Bennett, Michael C. Sachs, Joel Tarning, Andreas Mårtensson, Abdullah S. Ali, Anders Björkman

Publikováno v: BMC Medicine, Vol 16, Iss 1, Pp 1-15 (2018)

Abstract Background Mass drug administration (MDA) has the potential to interrupt malaria transmission and has been suggested as a tool for malaria elimination in low-endemic settings. This study aimed to determine the effectiveness and safety of two

Externí odkaz: https://doaj.org/article/7b4a3be0d0714832850288b4f3774dbf

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Akademický článek

A novel deep learning-based point-of-care diagnostic method for detecting Plasmodium falciparum with fluorescence digital microscopy.

Autor: Oscar Holmström, Sebastian Stenman, Antti Suutala, Hannu Moilanen, Hakan Kücükel, Billy Ngasala, Andreas Mårtensson, Lwidiko Mhamilawa, Berit Aydin-Schmidt, Mikael Lundin, Vinod Diwan, Nina Linder, Johan Lundin

Publikováno v: PLoS ONE, Vol 15, Iss 11, p e0242355 (2020)

BackgroundMalaria remains a major global health problem with a need for improved field-usable diagnostic tests. We have developed a portable, low-cost digital microscope scanner, capable of both brightfield and fluorescence imaging. Here, we used the

Externí odkaz: https://doaj.org/article/6beb0355669e47168cd042961ff2da19

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Akademický článek

Performance and Application of Commercially Available Loop-Mediated Isothermal Amplification (LAMP) Kits in Malaria Endemic and Non-Endemic Settings

Autor: Ulrika Morris, Berit Aydin-Schmidt

Publikováno v: Diagnostics, Vol 11, Iss 2, p 336 (2021)

Loop-mediated isothermal amplification (LAMP) is a sensitive molecular tool suitable for use as a near point-of-care test for the diagnosis of malaria. Recent meta-analyses have detailed high sensitivity and specificity of malaria LAMP when compared

Externí odkaz: https://doaj.org/article/41043f077e3447bc8a0028506d955e81

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Akademický článek

Field Evaluation of a High Throughput Loop Mediated Isothermal Amplification Test for the Detection of Asymptomatic Plasmodium Infections in Zanzibar.

Autor: Berit Aydin-Schmidt, Ulrika Morris, Xavier C Ding, Irina Jovel, Mwinyi I Msellem, Daniel Bergman, Atiqul Islam, Abdullah S Ali, Spencer Polley, Iveth J Gonzalez, Andreas Mårtensson, Anders Björkman

Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0169037 (2017)

BACKGROUND:New field applicable diagnostic tools are needed for highly sensitive detection of residual malaria infections in pre-elimination settings. Field performance of a high throughput DNA extraction system for loop mediated isothermal amplifica

Externí odkaz: https://doaj.org/article/584540cf4abd4b4fbda5af89590d40e6

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Chloroquine-susceptible and -resistant Plasmodium falciparum strains survive high chloroquine concentrations by becoming dormant but are eliminated by prolonged exposure

Autor: Johan Ursing, Rasmus Johns, Berit Aydin-Schmidt, Carla Calçada, Poul-Erik Kofoed, Najia Karim Ghanchi, Maria Isabel Veiga, Lars Rombo

Publikováno v: Ursing, J, Johns, R, Aydin-Schmidt, B, Calçada, C, Kofoed, P E, Ghanchi, N K, Veiga, M I & Rombo, L 2022, ' Chloroquine-susceptible and-resistant Plasmodium falciparum strains survive high chloroquine concentrations by becoming dormant but are eliminated by prolonged exposure ', The Journal of antimicrobial chemotherapy, vol. 77, no. 4, pp. 1005-1011 . https://doi.org/10.1093/jac/dkac008

BackgroundPlasmodium falciparum strains that are resistant to standard-dose chloroquine can be treated by higher chloroquine concentrations maintained for a longer time in vivo.ObjectivesTo determine the relative importance of chloroquine concentrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e3e28ca69bac9a45d17778c3994273
https://findresearcher.sdu.dk:8443/ws/files/201618245/Open_Access_Version.pdf

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Akademický článek

SYBR Green real-time PCR-RFLP assay targeting the plasmodium cytochrome B gene--a highly sensitive molecular tool for malaria parasite detection and species determination.

Autor: Weiping Xu, Ulrika Morris, Berit Aydin-Schmidt, Mwinyi I Msellem, Delér Shakely, Max Petzold, Anders Björkman, Andreas Mårtensson

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120210 (2015)

A prerequisite for reliable detection of low-density Plasmodium infections in malaria pre-elimination settings is the availability of ultra-sensitive and high-throughput molecular tools. We developed a SYBR Green real-time PCR restriction fragment le

Externí odkaz: https://doaj.org/article/af6d2709037f424195e5b5d8964c51b0

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Detection of Plasmodium falciparum by Light Microscopy, Loop-Mediated Isothermal Amplification, and Polymerase Chain Reaction on Day 3 after Initiation of Artemether–Lumefantrine Treatment for Uncomplicated Malaria in Bagamoyo District, Tanzania: A Comparative Trial

Autor: Bruno P. Mmbando, Billy Ngasala, Berit Aydin-Schmidt, Lwidiko E. Mhamilawa, Ulrika Morris

Publikováno v: The American Journal of Tropical Medicine and Hygiene. 101:1144-1147

Microscopy-determined Plasmodium falciparum positivity rates exceeding 10% on day 3 after initiation of artemisinin-based combination therapy (ACT) is an important indicator of artemisinin resistan ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87d5a88ff94196bbc10e3be79047b70c
https://doi.org/10.4269/ajtmh.19-0298

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Akademický článek

Loop mediated isothermal amplification (LAMP) accurately detects malaria DNA from filter paper blood samples of low density parasitaemias.

Autor: Berit Aydin-Schmidt, Weiping Xu, Iveth J González, Spencer D Polley, David Bell, Delér Shakely, Mwinyi I Msellem, Anders Björkman, Andreas Mårtensson

Publikováno v: PLoS ONE, Vol 9, Iss 8, p e103905 (2014)

Loop mediated isothermal amplification (LAMP) provides an opportunity for improved, field-friendly detection of malaria infections in endemic areas. However data on the diagnostic accuracy of LAMP for active case detection, particularly low-density p

Externí odkaz: https://doaj.org/article/d6d28db795f946a184eaae5dd3e1d44c

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