Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Berglind Osk, Einarsdottir"'
Autor:
Jiyeon Choi, Eiríkur Steingrímsson, Berglind Osk Einarsdottir, Mai Xu, Matthew Law, Mark M. Iles, D T Bishop, Michael A. Kovacs, Kevin M. Brown, Tongwu Zhang, K.L. Jones, Ramile Dilshat, Malasky M, Chowdhury S, Alisa M. Goldstein, Jianxin Shi, Maria Teresa Landi
While expression quantitative trait loci (eQTL) have been powerful in identifying susceptibility genes from genome-wide association studies (GWAS) findings, most trait-associated loci are not explained by eQTL alone. Alternative QTLs including DNA me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::529ba8f62e1e2d644281fa534a4da0c3
https://doi.org/10.1101/2021.03.23.436704
https://doi.org/10.1101/2021.03.23.436704
Autor:
Ramile Dilshat, Mark M. Iles, Alisa M. Goldstein, D. Timothy Bishop, Jianxin Shi, Jiyeon Choi, Matthew Law, Eiríkur Steingrímsson, Kristine Jones, Tongwu Zhang, Salma Chowdhury, Maria Teresa Landi, Michael A. Kovacs, Michael Malasky, Kevin M. Brown, Berglind Osk Einarsdottir, Mai Xu
Publikováno v:
Am J Hum Genet
Although expression quantitative trait loci (eQTLs) have been powerful in identifying susceptibility genes from genome-wide association study (GWAS) findings, most trait-associated loci are not explained by eQTLs alone. Alternative QTLs, including DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661543a33b3ba564affafcfa7acdc00f
https://pubmed.ncbi.nlm.nih.gov/34293285
https://pubmed.ncbi.nlm.nih.gov/34293285
Autor:
Phil F. Cheng, Colin Kenny, Ossia M. Eichhoff, Kritika Kirty, Marie de Tayrac, Berglind Osk Einarsdottir, Katrin Möller, Robert A. Cornell, Eiríkur Steingrímsson, Margret H. Ogmundsdottir, Ilse Gerritsen, Valerie Fock, Sara Sigurbjörnsdóttir, Romain Maurice Jacques Lasseur, Philipp Cerny, Mitchell P. Levesque, Erna Magnúsdóttir, E. Elizabeth Patton, Ramile Dilshat, Lionel Larue, Jana Travnickova
Publikováno v:
eLife
eLife, 2021, 10, ⟨10.7554/eLife.63093⟩
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.63093⟩
eLife, Vol 10 (2021)
MITF reprograms the extracellular matrix and focal adhesion in melanoma
eLife, 2021, 10, ⟨10.7554/eLife.63093⟩
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.63093⟩
eLife, Vol 10 (2021)
MITF reprograms the extracellular matrix and focal adhesion in melanoma
The microphthalmia associated transcription factor (MITF) is a critical regulator of melanocyte development and differentiation. It also plays an important role in melanoma where it has been described as a molecular rheostat that, depending on activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdab25a0704ebb828e48fae1ab622ae
https://hal.science/hal-03134824
https://hal.science/hal-03134824
Autor:
Valerie Fock, Romain Maurice Jacques Lasseur, Erna Magnúsdóttir, Margret H. Ogmundsdottir, Mitchell P. Levesque, Robert A. Cornell, Ossia M. Eichhoff, E. Elizabeth Patton, Eiríkur Steingrímsson, Sara Sigurbjörnsdóttir, Katrin Möller, Berglind Osk Einarsdottir, Ilse Gerritsen, Ramile Dilshat, Lionel Larue, Marie de Tayrac, Jana Travnickova, Phil F. Cheng, Colin Kenny, Philipp Cerny, Kritika Kirty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84159e8a30c9a5ec48bbed32b5796d0
https://doi.org/10.7554/elife.63093.sa2
https://doi.org/10.7554/elife.63093.sa2
Autor:
Suman Mitra, Per Lindnér, Elin M. V. Forsberg, Erik Larsson, Lars Ny, Vasu R. Sah, Ulrika Stierner, Ganesh Vilas Shelke, Henrik Jespersen, Joakim Karlsson, Samuel Alsén, Lisa M. Nilsson, Berglind Osk Einarsdottir, Jonas Nilsson, Roger Olofsson Bagge, Charlotta All-Eriksson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Metastatic uveal melanoma is less well understood than its primary counterpart, has a distinct biology compared to skin melanoma, and lacks effective treatments. Here we genomically profile metastatic tumors and infiltrating lymphocytes. BAP1 alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb84a46bd7d2752f2c6521d638f24d81
https://doi.org/10.1038/s41467-020-15606-0
https://doi.org/10.1038/s41467-020-15606-0
Autor:
Therese Pham, Kumar Sanjiv, T. Meijer, Jonas Nilsson, Christina Kalderén, Rozbeh Jafari, Fabienne Z. Gaugaz, Torkild Visnes, Annika Lindqvist, Prasad B. Wakchaure, Aleksandr Manoilov, Per Artursson, Gianluca Maddalo, U. Warpman Berglund, Olov A. Wallner, Pawel Baranczewski, V. Nagpal, Azita Rasti, Aljona Saleh, Elisee Wiita, Sean G. Rudd, Ann-Sofie Jemth, Martin Henriksson, Ingrid Almlöf, Helge Gad, Camilla Göktürk, Tobias Koolmeister, Alexey Chernobrovkin, Evert Homan, Thomas Helleday, Vassilis G. Gorgoulis, Lars Bräutigam, Berglind Osk Einarsdottir, Brinton Seashore-Ludlow, Y. Kallberg, Olga Loseva, T-C Lee, Janne Lehtiö, Sanjay R. Borhade, Björn Platzack, Patrick Herr, Anne M. Filppula, Karl S. A. Vallin, Roman A. Zubarev, Ioannis S. Pateras, Martin Scobie, Nicolaas G. M. Schipper
Publikováno v:
Annals of Oncology
Annals of oncology : official journal of the European Society for Medical Oncology
Annals of oncology : official journal of the European Society for Medical Oncology
Background: Previously we showed cancer cells rely on the MTH1 protein to prevent incorporation of otherwise deadly oxidised nucleotides into DNA and we developed MTH1 inhibitors which selectively kill cancer cells. Recently several new and potent in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a71ea01ac7d0533472602aea288f43
https://doi.org/10.1093/annonc/mdw429
https://doi.org/10.1093/annonc/mdw429
Molecular profiling of driver events and tumor-infiltrating lymphocytes in metastatic uveal melanoma
Autor:
Ulrika Stierner, Samuel Alsén, Roger Olofsson Bagge, Henrik Jespersen, Joakim Karlsson, Lisa M. Nilsson, Jonas Nilsson, Suman Mitra, Berglind Osk Einarsdottir, Charlotta All-Eriksson, Per Lindnér, Elin M. V. Forsberg, Lars Ny, Erik Larsson, Vasu R. Sah, Ganesh Vilas Shelke
Uveal melanoma (UM) is a rare form of melanoma with a genetics and immunology that is different from skin melanoma. Previous studies have identified genetic driver events of early stage disease when the tumor is confined to the eye. However due to la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fe72c59bd51e008ff246d89d1ce149
https://doi.org/10.1101/742023
https://doi.org/10.1101/742023
Autor:
Mattias F. Lindberg, Thomas Helleday, Olof Wallner, Henrik Jespersen, Louise Carstam, Siggeir F. Brynjolfsson, Ulrika Stierner, Martin Scobie, Joakim Karlsson, Lars Ny, Elisa Funck-Brentano, Ulrika Warpman Berglund, Erik Larsson, Berglind Osk Einarsdottir, Elin M. V. Söderberg, Roger Olofsson Bagge, Jonas Nilsson, Tobias Koolmeister, Lisa M. Nilsson
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 8, Pp 1-12 (2018)
Cell Death and Disease, Vol 9, Iss 8, Pp 1-12 (2018)
Karonudib (TH1579) is a novel compound that exerts anti-tumor activities and has recently entered phase I clinical testing. The aim of this study was to conduct a pre-clinical trial in patient-derived xenografts to identify the possible biomarkers of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87aa8af131a7bac3a79c57810b15f8cc
http://europepmc.org/articles/PMC6057880
http://europepmc.org/articles/PMC6057880
Autor:
Somsundar Veppil Muralidharan, Cecilia Lässer, Taral R. Lunavat, Yong Song Gho, Roger Olofsson Bagge, Robyn A. Sharples, Andrew F. Hill, Lesley Cheng, Jan Lötvall, Berglind Osk Einarsdottir, Jonas Nilsson
Publikováno v:
Proceedings of the National Academy of Sciences. 114
The BRAF inhibitors vemurafenib and dabrafenib can be used to treat patients with metastatic melanomas harboring BRAFV600 mutations. Initial antitumoral responses are often seen, but drug-resistant clones with reactivation of the MEK-ERK pathway soon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a14ebaa7b3aebb4cbc4a0bd8f67b9c
https://doi.org/10.1073/pnas.1705206114
https://doi.org/10.1073/pnas.1705206114
Autor:
Helge, Gad, Tobias, Koolmeister, Ann-Sofie, Jemth, Saeed, Eshtad, Sylvain A, Jacques, Cecilia E, Ström, Linda M, Svensson, Niklas, Schultz, Thomas, Lundbäck, Berglind Osk, Einarsdottir, Aljona, Saleh, Camilla, Göktürk, Pawel, Baranczewski, Richard, Svensson, Ronnie P-A, Berntsson, Robert, Gustafsson, Kia, Strömberg, Kumar, Sanjiv, Marie-Caroline, Jacques-Cordonnier, Matthieu, Desroses, Anna-Lena, Gustavsson, Roger, Olofsson, Fredrik, Johansson, Evert J, Homan, Olga, Loseva, Lars, Bräutigam, Lars, Johansson, Andreas, Höglund, Anna, Hagenkort, Therese, Pham, Mikael, Altun, Fabienne Z, Gaugaz, Svante, Vikingsson, Bastiaan, Evers, Martin, Henriksson, Karl S A, Vallin, Olov A, Wallner, Lars G J, Hammarström, Elisee, Wiita, Ingrid, Almlöf, Christina, Kalderén, Hanna, Axelsson, Tatjana, Djureinovic, Jordi, Carreras Puigvert, Maria, Häggblad, Fredrik, Jeppsson, Ulf, Martens, Cecilia, Lundin, Bo, Lundgren, Ingrid, Granelli, Annika, Jenmalm Jensen, Per, Artursson, Jonas A, Nilsson, Pål, Stenmark, Martin, Scobie
Publikováno v:
Nature. 544(7651)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a849c4dcef26131d22c77ff42f3cbc8e
https://pubmed.ncbi.nlm.nih.gov/24695224
https://pubmed.ncbi.nlm.nih.gov/24695224