Northstar enables automatic classification of known and novel cell types from tumor samples.

Autor: Zanini F; Department of Bioengineering, Stanford University, Stanford, CA, USA. fabio.zanini@unsw.edu.au.; Prince of Wales Clinical School and Adult Cancer Program, UNSW, Sydney, Australia. fabio.zanini@unsw.edu.au., Berghuis BA; Department of Bioengineering, Stanford University, Stanford, CA, USA., Jones RC; Department of Bioengineering, Stanford University, Stanford, CA, USA., Nicolis di Robilant B; Department of Oncology, Stanford School of Medicine, Stanford, CA, USA., Nong RY; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Immunology, Genetics and Pathology and SciLifeLab, Uppsala University, Uppsala, Sweden., Norton JA; Department of Surgery, Stanford Pancreas Cancer Research Group, General Surgery, Stanford University School of Medicine, Stanford, CA, USA., Clarke MF; Department of Oncology, Stanford School of Medicine, Stanford, CA, USA., Quake SR; Department of Bioengineering, Stanford University, Stanford, CA, USA. quake@stanford.edu.; Department of Applied Physics, Stanford University, Stanford, CA, USA. quake@stanford.edu.; Chan Zuckerberg Biohub, San Francisco, CA, USA. quake@stanford.edu.

Publikováno v: Scientific reports [Sci Rep] 2020 Sep 17; Vol. 10 (1), pp. 15251. Date of Electronic Publication: 2020 Sep 17.

What is all this fuss about Tus? Comparison of recent findings from biophysical and biochemical experiments.

Autor: Berghuis BA; a Department of Bionanoscience , Kavli institute of Nanoscience, Delft University of Technology , Delft , the Netherlands., Raducanu VS; b Division of Biological and Environmental Science and Engineering , King Abdullah University of Science and Technology , Thuwal , Saudi Arabia., Elshenawy MM; b Division of Biological and Environmental Science and Engineering , King Abdullah University of Science and Technology , Thuwal , Saudi Arabia., Jergic S; c Centre for Medical and Molecular Bioscience , University of Wollongong , Wollongong , New South Wales , Australia., Depken M; a Department of Bionanoscience , Kavli institute of Nanoscience, Delft University of Technology , Delft , the Netherlands., Dixon NE; c Centre for Medical and Molecular Bioscience , University of Wollongong , Wollongong , New South Wales , Australia., Hamdan SM; b Division of Biological and Environmental Science and Engineering , King Abdullah University of Science and Technology , Thuwal , Saudi Arabia., Dekker NH; a Department of Bionanoscience , Kavli institute of Nanoscience, Delft University of Technology , Delft , the Netherlands.

Publikováno v: Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2018 Feb; Vol. 53 (1), pp. 49-63. Date of Electronic Publication: 2017 Nov 06.

Backtracking behavior in viral RNA-dependent RNA polymerase provides the basis for a second initiation site.

Autor: Dulin D; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Vilfan ID; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Berghuis BA; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Poranen MM; Department of Biosciences, University of Helsinki, Viikki Biocenter 1, P.O. Box 56 (Viikinkaari 9), 00014 Helsinki, Finland., Depken M; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Dekker NH; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2015 Dec 02; Vol. 43 (21), pp. 10421-9. Date of Electronic Publication: 2015 Oct 22.

Strand separation establishes a sustained lock at the Tus-Ter replication fork barrier.

Autor: Berghuis BA; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands., Dulin D; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands., Xu ZQ; Centre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia., van Laar T; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands., Cross B; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands., Janissen R; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands., Jergic S; Centre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia., Dixon NE; Centre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, Australia., Depken M; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands., Dekker NH; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2015 Aug; Vol. 11 (8), pp. 579-85. Date of Electronic Publication: 2015 Jul 06.

A force calibration standard for magnetic tweezers.

Autor: Yu Z; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Dulin D; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Cnossen J; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Köber M; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., van Oene MM; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Ordu O; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Berghuis BA; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Hensgens T; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Lipfert J; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands., Dekker NH; Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands.

Publikováno v: The Review of scientific instruments [Rev Sci Instrum] 2014 Dec; Vol. 85 (12), pp. 123114.