Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Berger Dan Maarten"'
Autor:
Berger Dan Maarten, Minu Dutia, Gary Harold Birnberg, Frenel Fils Demorin, Yanong D. Wang, Dennis Powell
Publikováno v:
Synthesis. 2003:1712-1716
The regioselective synthesis of compound 3, a potent Src kinase inhibitor is described. A key step in this synthesis is the regioselective thermal rearrangement of a substituted benzocyclobutene to provide a 2,3,6,7-tetrasubstituted naphthalene. An e
Autor:
Dennis Powell, Minu Dutia, Berger Dan Maarten, Frenel Fils Demorin, Jennifer Weber, Yuri Raifeld, Allan Wissner, Frank Boschelli
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:2989-2992
A series of substituted 4-anilino-7-phenyl-3-quinolinecarbonitriles has been prepared as Src kinase inhibitors. Optimal activity is observed with compounds that have basic amines attached via the para position of the 7-phenyl ring, and a hydrogen ato
Publikováno v:
Helvetica Chimica Acta. 82:326-337
Publikováno v:
Helvetica Chimica Acta. 81:1792-1802
Publikováno v:
Helvetica Chimica Acta. 79:192-202
Reaction of ‘Push-Pull’ Enynes with Acids. First Observation of a Rearrangement of 5-Chloro-5-(dialkylamino)pentadienals ‘Push-pull’-enynes 7 react easily with HCl as well as with AcOH to give 5-amino-5-chloropentadienals 8 and 5-(acetoxy)-5-
Publikováno v:
Helvetica Chimica Acta. 79:179-191
Synthesis of ‘Push-Pull’ Enynes ‘Push-pull’ enynes 1a–1f are easily available by Pd catalyzed coupling of stannyl-ynamines 15 and silylynamines 16 with β-iodo-enones 8 (Schemes 7 and 8).
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 30
Publikováno v:
ChemInform. 30