KRAS and GNAS mutations in cell-free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms-an observational pilot study.

Autor: Nitschke C; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany.; Mildred Scheel Cancer Career Center, Hamburg, Germany.; Institute of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany., Tölle M; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany.; Institute of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany., Walter P; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany.; Institute of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany., Meißner K; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany.; Institute of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany., Goetz M; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany., Kropidlowski J; Department of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany., Berger AW; Department of Internal Medicine I, Ulm University, Germany.; Department of Internal Medicine II, Evangelisches Krankenhaus Königin Elisabeth Herzberge, Berlin, Germany., Izbicki JR; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany., Nickel F; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany., Hackert T; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany., Pantel K; Institute of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany., Wikman H; Institute of Tumor Biology, University Hospital Hamburg-Eppendorf, Germany., Uzunoglu FG; Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany.

Publikováno v: Molecular oncology [Mol Oncol] 2024 Sep 01. Date of Electronic Publication: 2024 Sep 01.

Prediction of resistance to bevacizumab plus FOLFOX in metastatic colorectal cancer-Results of the prospective multicenter PERMAD trial.

Autor: Seufferlein T; Department of Internal Medicine I, Ulm University Hospital, Ulm, Germany., Lausser L; Institute of Medical Systems Biology, Ulm University, Ulm, Germany.; Faculty of Computer Science, Technische Hochschule Ingolstadt, Ingolstadt, Germany., Stein A; Hematology-Oncology Practice Eppendorf, University Cancer Center Hamburg, Hamburg, Germany., Arnold D; Asklepios Cancer Center Hamburg, AK Altona, Hamburg, Germany., Prager G; Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria., Kasper-Virchow S; Medical Oncology, University Hospital Essen West German Cancer Center, Essen, Germany., Niedermeier M; Private Practice, Memmingen, Germany., Müller L; Private Practice, Leer, Germany., Kubicka S; Cancer Center Reutlingen, Reutlingen Hospital, Reutlingen, Germany., König A; Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Goettingen, Göttingen, Germany., Büchner-Steudel P; Internal Medicine I, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Wille K; Hematology, Oncology, University Hospital Ruhr-University-Bochum, Minden, Germany., Berger AW; Department of Internal Medicine I, Ulm University Hospital, Ulm, Germany., Kestler AMR; Department of Internal Medicine I, Ulm University Hospital, Ulm, Germany., Kraus JM; Institute of Medical Systems Biology, Ulm University, Ulm, Germany., Werle SD; Institute of Medical Systems Biology, Ulm University, Ulm, Germany., Perkhofer L; Department of Internal Medicine I, Ulm University Hospital, Ulm, Germany., Ettrich TJ; Department of Internal Medicine I, Ulm University Hospital, Ulm, Germany., Kestler HA; Institute of Medical Systems Biology, Ulm University, Ulm, Germany.

Publikováno v: PloS one [PLoS One] 2024 Jun 14; Vol. 19 (6), pp. e0304324. Date of Electronic Publication: 2024 Jun 14 (Print Publication: 2024).

Endoscopic trans-anal tube placement is a safe and helpful tool for colonic decompression: final results of a standardized single-centre retrospective assessment of 125 patients.

Autor: Horn A; Praxis für Gastroenterologie, Berlin, Germany.; Department of Gastroenterology, Vivantes Klinikum im Friedrichshain, Berlin, Germany., Sabet M; Department of General Surgery, Vivantes Klinikum im Friedrichshain, Berlin, Germany., Roghmann F; Department of Urology, Ruhr University of Bochum Faculty of Medicine, Bochum, Germany., Meves V; Department of Gastroenterology, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany., Loss M; Department of General Surgery, Vivantes Klinikum im Friedrichshain, Berlin, Germany., Hochberger J; Department of Gastroenterology, Vivantes Klinikum im Friedrichshain, Berlin, Germany., Benckert C; Department of General Surgery, Vivantes Klinikum im Friedrichshain, Berlin, Germany., Berger AW; Department of Gastroenterology, Vivantes Klinikum im Friedrichshain, Berlin, Germany.; Department of internal medicine, Ulm University Medical Faculty, Ulm, Germany.

Publikováno v: Zeitschrift fur Gastroenterologie [Z Gastroenterol] 2024 Feb; Vol. 62 (2), pp. 175-182. Date of Electronic Publication: 2023 Jan 20.

Perioperative or only adjuvant gemcitabine plus nab-paclitaxel for resectable pancreatic cancer (NEONAX)-a randomized phase II trial of the AIO pancreatic cancer group.

Autor: Seufferlein T; Department of Internal Medicine I, Ulm University, Ulm, Germany. Electronic address: thomas.seufferlein@uniklinik-ulm.de., Uhl W; Department of General and Visceral Surgery, St. Josef-Hospital Bochum, Ruhr-University Bochum, Bochum, Germany., Kornmann M; Department of General and Visceral Surgery, Ulm University, Ulm, Germany., Algül H; CCC Munich-TUM and Department of Internal Medicine II, TUM, Munich, Germany., Friess H; Department of General and Visceral Surgery, TUM, Munich, Germany., König A; Department of Gastroenterology, GI-Oncology and Endocrinology, University Medical Center, Göttingen, Germany., Ghadimi M; Department of General and Visceral Surgery, University Medical Center Göttingen, Göttingen, Germany., Gallmeier E; Department of Gastroenterology and Endocrinology, University of Marburg, Marburg, Germany., Bartsch DK; Department of General and Visceral Surgery, University of Marburg, Marburg, Germany., Lutz MP; Department of Gastroenterology, Caritasklinik St. Theresia, Saarbrücken, Germany., Metzger R; Department of General and Visceral Surgery, Caritasklinik St. Theresia, Saarbrücken, Germany., Wille K; Department of Hematology, Oncology, Hemostaseology and Palliative Care, Johannes Wesling Medical Center Minden, Ruhr-University Bochum, Bochum, Germany., Gerdes B; Department of General and Visceral Surgery Minden, Ruhr-University Bochum, Minden, Germany., Schimanski CC; Department of Internal Medicine and Gastroenterology, Darmstadt Hospital, Darmstadt, Germany., Graupe F; Department of General and Visceral Surgery, Darmstadt Hospital, Darmstadt, Germany., Kunzmann V; Department of Internal Medicine II, Julius Maximilians University, Würzburg, Germany., Klein I; Department of General, Visceral, Vascular and Pediatric Surgery, Julius Maximilians University, Würzburg, Germany., Geissler M; Department of Hematology and Oncology, Esslingen Hospital, Esslingen, Germany., Staib L; Department of Surgery, Esslingen Hospital, Esslingen, Germany., Waldschmidt D; Department of Gastroenterology and Hepatology, University of Cologne, Cologne, Germany., Bruns C; Department of Visceral Surgery, University of Cologne, Cologne, Germany., Wittel U; Department of General and Visceral Surgery, University of Freiburg, Freiburg, Germany., Fichtner-Feigl S; Department of General and Visceral Surgery, University of Freiburg, Freiburg, Germany., Daum S; Department for Gastroenterology, Rheumatology and Infectology, Charite University Hospital Berlin, Berlin, Germany., Hinke A; Biostatistics, CCRC Cancer Clinical Research Consulting, Düsseldorf, Germany., Blome L; Biometrics, ClinAssess Gesellschaft für klinische Forschung mbH, Leverkusen, Germany., Tannapfel A; Institute of Pathology, Ruhr-University Bochum, Bochum, Germany., Kleger A; Department of Internal Medicine I, Ulm University, Ulm, Germany., Berger AW; Department of Internal Medicine I, Ulm University, Ulm, Germany., Kestler AMR; Department of Internal Medicine I, Ulm University, Ulm, Germany., Schuhbaur JS; Department of Internal Medicine I, Ulm University, Ulm, Germany., Perkhofer L; Department of Internal Medicine I, Ulm University, Ulm, Germany., Tempero M; UCSF Department of Medicine, University of California San Francisco, San Francisco, USA., Reinacher-Schick AC; Department of Hematology, Oncology and Palliative Care, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany., Ettrich TJ; Department of Internal Medicine I, Ulm University, Ulm, Germany.

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2023 Jan; Vol. 34 (1), pp. 91-100. Date of Electronic Publication: 2022 Oct 07.

Prognosis and tumor biology of pancreatic cancer patients with isolated lung metastases: translational results from the German multicenter AIO-YMO-PAK-0515 study.

Autor: Kruger SF; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany. Electronic address: stephan.florian.kruger@gmail.com., Lohneis A; Charité-Universitätsmedizin Berlin, Department of Medical Oncology and Hematology, Berlin, Germany; Department of Internal Medicine I, University Hospital Cologne, Cologne, Germany., Abendroth A; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Berger AW; Department of Internal Medicine I, Ulm University, Ulm, Germany., Ettrich TJ; Department of Internal Medicine I, Ulm University, Ulm, Germany., Waidmann O; Department of Internal Medicine I, University Hospital Frankfurt, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany; University Cancer Centre Frankfurt, University Hospital Frankfurt, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany., Kapp M; Division of Medical Oncology, Department of Internal Medicine II, University Hospital Wuerzburg and Comprehensive Cancer Center Mainfranken, Wuerzburg, Germany., Steiner B; Department of Hematology and Oncology, University of Rostock, Rostock, Germany., Kumbrink J; Institute of Pathology, Ludwig-Maximilians-University of Munich, Munich, Germany., Reischer A; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany., Haas M; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany., Westphalen CB; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Zhang D; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany., Miller-Phillips L; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany., Burger PJ; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany., Kobold S; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany; Center for Integrated Protein Science Munich and Division of Clinical Pharmacology, Department of Medicine IV, Klinikum der Ludwig-Maximilians-University of Munich, Munich, Germany., Werner J; Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany., Subklewe M; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., von Bergwelt-Baildon M; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Kunzmann V; Division of Medical Oncology, Department of Internal Medicine II, University Hospital Wuerzburg and Comprehensive Cancer Center Mainfranken, Wuerzburg, Germany., Seufferlein T; Department of Internal Medicine I, Ulm University, Ulm, Germany., Siveke JT; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Sinn M; Charité-Universitätsmedizin Berlin, Department of Medical Oncology and Hematology, Berlin, Germany; Department of Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Heinemann V; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Ormanns S; Institute of Pathology, Ludwig-Maximilians-University of Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Boeck S; Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.

Publikováno v: ESMO open [ESMO Open] 2022 Feb; Vol. 7 (1), pp. 100388. Date of Electronic Publication: 2022 Feb 02.