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pro vyhledávání: '"Berger, Alice H."'
Autor:
Parrish, Phoebe C. R., Groso, Daniel J., Thomas, James D., Bradley, Robert K., Berger, Alice H.
We developed pgMAP, an analysis pipeline to map gRNA sequencing reads from dual-targeting CRISPR screens. pgMAP output includes a dual gRNA read counts table and quality control metrics including the proportion of correctly-paired reads and CRISPR li
Externí odkaz:
http://arxiv.org/abs/2306.00944
Autor:
Riley, Amanda K., Grant, Michael, Snell, Aidan, Cromwell, Elizabeth, Vichas, Athea, Moorthi, Sitapriya, Rominger, Callie, Modukuri, Shrikar P., Urisman, Anatoly, Castel, Pau, Wan, Lixin, Berger, Alice H.
Publikováno v:
In iScience 16 August 2024 27(8)
Akademický článek
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Autor:
Parrish, Phoebe C.R., Thomas, James D., Gabel, Austin M., Kamlapurkar, Shriya, Bradley, Robert K., Berger, Alice H.
Publikováno v:
In Cell Reports 31 August 2021 36(9)
Akademický článek
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Autor:
Moorthi, Sitapriya, Paguirigan, Amy, Ko, Minjeong, Pettinger, Mary, Hoge, Anna C. H., Nag, Anwesha, Patel, Neil A., Wu, Feinan, Sather, Cassie, Fitzgibbon, Matthew P., Thorner, Aaron R., Anderson, Garnet L., Ha, Gavin, Berger, Alice H.
Publikováno v:
bioRxiv
SummaryLung cancer in never-smokers disproportionately affects older women. To understand the mutational landscape of this cohort, we performed detailed genome characterization of 73 lung adenocarcinomas from participants of the Women’s Health Init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475dfabfd9ba20447b9168482c6d640f
https://doi.org/10.1101/2023.01.05.522947
https://doi.org/10.1101/2023.01.05.522947
Additional file 4: Supplementary Fig. 3. A) Volcano plot of differentially expressed genes in wild-type MYC overexpressing cells. Blue = downregulated transcripts. Red = upregulated transcripts. Green = transcripts in mSigDB hallmark gene sets MYC ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f1428a382f3b85f7c5fa96e8dc5eb6
Additional file 1: Supplementary Fig. 1. A) Volcano plot of differential protein abundance in KRASG12V and KRASQ61H cells compared to KRASWT cells. Labeled in red are SR proteins. B) Volcano plot of phosphorylation of phosphosites in KRASG12V and KRA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b6581560180ca12c4f7147be110b9d
Additional file 5: Supplementary Fig. 4. A) Number of events differentially spliced between cells with genetic perturbations and cells with vector controls. Colors represent 5 major alternative splicing event categories. Wild-type alleles of transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976462c16a0e54c5b00d59b08f3ba730
Additional file 7: Supplementary Fig. 5. A) mRNA expression of splicing factors SF3B1, SRSF1, and SRSF7. B) End-point PCR gel detecting MAZ-1 and MAZ-2 isoforms in AALE cells overexpressing vector, KRAS, or RIT1 variants. C) Differential splicing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8f67984c8b1cf7c823891cc5b7da27