Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Berg, R.J.B.H.N. van den"'
Autor:
Liu, B., Mechelen, J. van, Berg, R.J.B.H.N. van den, Nieuwendijk, A.M.C.H. van den, Aerts, J.M.F.G., Marel, G.A. van der, Codée, J.D.C., Overkleeft, H.S.
Publikováno v:
European Journal of Organic Chemistry, 2019(1), 118-129
Iminosugars are an important class of natural products and have been subject to extensive studies in organic synthesis, bioorganic chemistry and medicinal chemistry, yet only a limited number of these studies are on glycosylated iminosugars. Here, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f825f33ec6a05618b0a16aee43c8deed
http://hdl.handle.net/1887/74459
http://hdl.handle.net/1887/74459
Autor:
Hoogendoorn, S., Mock, E.D., Strijland, A., Donker-Koopman, W.E., Elst, H. van den, Berg, R.J.B.H.N. van den, Aerts, J.M.F.G., Marel, G.A. van der, Overkleeft, H.S.
Publikováno v:
European Journal of Organic Chemistry, 2015(20), 4437-4446
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::632c83108f6c75c6db34bfd8008d5047
https://doi.org/10.1002/ejoc.201500364
https://doi.org/10.1002/ejoc.201500364
Autor:
Wisse, P., Gold, H., Mirzaian, M., Guimaraes Da Lomba Ferraz, M.J., Lutteke, G., Berg, R.J.B.H.N. van den, Elst, H. van den, Lugtenburg, J., Marel, G.A. van der, Aerts, J.M.F.G., Codee, J.D.C., Overkleeft, H.S.
Publikováno v:
European Journal of Organic Chemistry, 2015(12), 2661-2677
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::983aef2d7b3ec1d067b6f7080fb88917
https://doi.org/10.1002/ejoc.201500025
https://doi.org/10.1002/ejoc.201500025
Autor:
Berg, R.J.B.H.N. van den, Noort, D., Milder-Enacache, E.S., Marel, G.A. van der, Boom, J.H. van, Benschop, H.P.
Publikováno v:
European Journal of Organic Chemistry, 10, 2593-2600
In order to develop a generic treatment for infections with Gram- negative bacteria, we developed a synthesis of 2-acylamino-deoxynojirimycin derivatives (17, 18, 19 and 20), which will be used as haptens for raising catalytic antibodies capable of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::76b4587d3933f7590ba90cd65aa80813
http://resolver.tudelft.nl/uuid:3778ec04-cacf-49a4-90c6-027c1eebad55
http://resolver.tudelft.nl/uuid:3778ec04-cacf-49a4-90c6-027c1eebad55
Autor:
Wendel, T.J.
Publikováno v:
None
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E. After remaining elusive for many years, in 2016, this enzyme was discovered to be responsible for the calcium-dependent formation of N-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2573b1f10c279a493bc2dea7e3dbfd1d
http://hdl.handle.net/1887/3576707
http://hdl.handle.net/1887/3576707
Autor:
Jiang, M.
Publikováno v:
None
Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2b3540cd5e11c81412312fe38d654252
http://hdl.handle.net/1887/3279133
http://hdl.handle.net/1887/3279133
Autor:
Liu, B.
Publikováno v:
None
This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars. In the studies described, 1-deoxynojirimycin (DNJ), and its known N-alkylated derivatives, served as starting points.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bf9bb4de2576fef3d4dd87f9c986515a
https://hdl.handle.net/1887/57984
https://hdl.handle.net/1887/57984