Výsledky vyhledávání - "Berendsen, Johanna T.W."

Akademický článek

A CRISPR/Cas12a-assisted in vitro diagnostic tool for identification and quantification of single CpG methylation sites

Autor: van Dongen, Jeanne E., Berendsen, Johanna T.W., Eijkel, Jan C.T., Segerink, Loes I.

Publikováno v: In Biosensors and Bioelectronics 15 December 2021 194

Digital single cancer biomarker detection by CRISPR/Cas sensing: Towards dynamic profiling for CpG methylation quantification

Autor: van Dongen, Jeanne Elisabeth, Berendsen, Johanna T.W., Eijkel, Jan C.T., Segerink, Loes

Publikováno v: NanoBioTech-Montreux Conference 2022

Introduction Cancer, as a disease, starts with a genetic change in the genome that results in the downregulation of genes involved in “normal” cell behavior. This genetic change can either be induced by a change in the DNA code (mutation) or epig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::9108be211cec766137ec19ce784d0494
https://research.utwente.nl/en/publications/b1e57725-8ce4-47f0-9a03-d80666b8762f

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Towards a multiplexed barcode CRISPR/Cas12a-Assisted platform for the identification and quantification of singele CpG Methylation Sites

Autor: van Dongen, Jeanne Elisabeth, Berendsen, Johanna T.W., Eijkel, Jan C.T., Segerink, Loes

Publikováno v: 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA, 741-742
STARTPAGE=741;ENDPAGE=742;TITLE=25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
ISSUE=25;TITLE=25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021

Here we demonstrate a method to discriminate single CpG site methylation in DNA by the use of methylation-sensitive restriction enzymes (MSREs) followed by Cas12a-assisted sensing, which can be used as biomarker for several diseases. We show prelimin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2e3bb8b1b9259a3d78fe355a5711bc5c
https://research.utwente.nl/en/publications/9bf93125-2130-40e0-875a-85591b6829fa

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Akademický článek

Point-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities.

Autor: van Dongen, Jeanne E.¹ (AUTHOR) j.e.vandongen@utwente.nl, Berendsen, Johanna T.W.¹ (AUTHOR), Steenbergen, Renske D.M.² (AUTHOR), Wolthuis, Rob M.F.³ (AUTHOR), Eijkel, Jan C.T.¹ (AUTHOR), Segerink, Loes I.¹ (AUTHOR)

Publikováno v: Biosensors & Bioelectronics. Oct2020, Vol. 166, pN.PAG-N.PAG. 1p.

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