Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Berend Snel"'
Autor:
Thomas A Richards, Laura Eme, John M Archibald, Guy Leonard, Susana M Coelho, Alex de Mendoza, Christophe Dessimoz, Pavel Dolezal, Lillian K Fritz-Laylin, Toni Gabaldón, Vladimír Hampl, Geert J P L Kops, Michelle M Leger, Purificacion Lopez-Garcia, James O McInerney, David Moreira, Sergio A Muñoz-Gómez, Daniel J Richter, Iñaki Ruiz-Trillo, Alyson E Santoro, Arnau Sebé-Pedrós, Berend Snel, Courtney W Stairs, Eelco C Tromer, Jolien J E van Hooff, Bill Wickstead, Tom A Williams, Andrew J Roger, Joel B Dacks, Jeremy G Wideman
Publikováno v:
PLoS Biology, Vol 22, Iss 11, p e3002917 (2024)
Understanding the origin of eukaryotic cells is one of the most difficult problems in all of biology. A key challenge relevant to the question of eukaryogenesis is reconstructing the gene repertoire of the last eukaryotic common ancestor (LECA). As d
Externí odkaz:
https://doaj.org/article/81517f9828814b7fb85e2a6a375c29e7
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Polycomb group proteins, as part of the Polycomb repressive complexes, are essential in gene repression through chromatin compaction by canonical PRC1, mono-ubiquitylation of histone H2A by non-canonical PRC1 and tri-methylation of histone H
Externí odkaz:
https://doaj.org/article/3f3f16f72ef44fc0b2a68f4ba68e0539
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract The endosymbiosis of an alpha-proteobacterium that gave rise to mitochondria was one of the key events in eukaryogenesis. One striking outcome of eukaryogenesis was a much more complex cell with a large genome. Despite the existence of many
Externí odkaz:
https://doaj.org/article/cd88a04c3b1f46e8a13c19d297748467
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 2, p e1011860 (2024)
The complex eukaryotic cell resulted from a merger between simpler prokaryotic cells, yet the role of the mitochondrial endosymbiosis with respect to other eukaryotic innovations has remained under dispute. To investigate how the regulatory challenge
Externí odkaz:
https://doaj.org/article/464a479093444293b425fab4989cc917
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Analysis of ancestral intron positions in two large sets of duplicated gene families suggests that introns may have originated earlier on in eukaryogenesis, before other complex eukaryotic features were established.
Externí odkaz:
https://doaj.org/article/826628e2cfdb456fbf8bf360df30b9d2
Publikováno v:
PLoS Biology, Vol 20, Iss 11, p e3001855 (2022)
The neuronal microtubule cytoskeleton is key to establish axon-dendrite polarity. Dendrites are characterized by the presence of minus-end out microtubules. However, the mechanisms that organize these microtubules with the correct orientation are sti
Externí odkaz:
https://doaj.org/article/151af1b17224400aaec8d00943bf58c5
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104633- (2022)
Summary: Polycomb Repressive Complex 2 (PRC2) catalyzes the mono-, di-, and trimethylation of histone protein H3 on lysine 27 (H3K27), which is strongly associated with transcriptionally silent chromatin. The functional core of PRC2 is highly conserv
Externí odkaz:
https://doaj.org/article/99df9ba793b643e2b3757e99a54fa917
Autor:
Samuel H. A. von der Dunk, Berend Snel
Publikováno v:
BMC Evolutionary Biology, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background Convergent and parallel evolution provide unique insights into the mechanisms of natural selection. Some of the most striking convergent and parallel (collectively recurrent) amino acid substitutions in proteins are adaptive, but
Externí odkaz:
https://doaj.org/article/c0b24be521324fbf9f0fbb25e698051a
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Phylogenetic profiling in eukaryotes is of continued interest to study and predict the functional relationships between proteins. This interest is likely driven by the increased number of available diverse genomes and computational methods to infer o
Externí odkaz:
https://doaj.org/article/387a44f5e5af48baa5bab948453a8d3d
Autor:
Jiajia Li, Tania Chroumpi, Sandra Garrigues, Roland S. Kun, Jiali Meng, Sonia Salazar-Cerezo, Maria Victoria Aguilar-Pontes, Yu Zhang, Sravanthi Tejomurthula, Anna Lipzen, Vivian Ng, Chaevien S. Clendinen, Nikola Tolić, Igor V. Grigoriev, Adrian Tsang, Miia R. Mäkelä, Berend Snel, Mao Peng, Ronald P. de Vries
Publikováno v:
Journal of Fungi, Vol 8, Iss 12, p 1315 (2022)
Fungi play a critical role in the global carbon cycle by degrading plant polysaccharides to small sugars and metabolizing them as carbon and energy sources. We mapped the well-established sugar metabolic network of Aspergillus niger to five taxonomic
Externí odkaz:
https://doaj.org/article/15ccf467cc8541aa866efcc08be28b02