IL-2 and IL-6 synergize to augment the pore-forming protein gene expression and cytotoxic potential of human peripheral blood T cells

Autor: Smyth, M. J., Ortaldo, J. R., Bere, W., Yagita, H., Okumura, K., Howard Young

Publikováno v: Scopus-Elsevier

Our previous studies have demonstrated that high dose IL-2 (1000 U/ml) alone can induce human peripheral blood T cell pore-forming protein (PFP) mRNA expression and cytotoxic potential. We now report that the levels of IL-2 needed to induce these eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4aa6d658c349e436cf44fbe9c6c3a6
https://doi.org/10.4049/jimmunol.145.4.1159

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The restricted expression of granzyme M in human lymphocytes.

Autor: Sayers TJ; Intramural Research Support Program, Science Applications International Corporation-Frederick, Laboratory of Experimental Immunology, Division of Basic Sciences, National Cancer Institute, Frederick, MD 21702-1201, USA. sayers@mail.ncifcrf.gov, Brooks AD, Ward JM, Hoshino T, Bere WE, Wiegand GW, Kelly JM, Smyth MJ

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2001 Jan 15; Vol. 166 (2), pp. 765-71.

Influence of adoptively transferred thioglycollate-elicited peritoneal macrophages on metastasis formation in mice with depressed or stimulated NK activity.

Autor: Gorelik E, Wiltrout RH, Brunda MJ, Bere WE, Herberman RB

Publikováno v: Clinical & experimental metastasis [Clin Exp Metastasis] 1985 Apr-Jun; Vol. 3 (2), pp. 111-23.