Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Berdine van der Steen"'
Autor:
Roberto Stabile, Mario Román Cabezas, Mathijs P. Verhagen, Francesco A. Tucci, Thierry P. P. van den Bosch, Maria J. De Herdt, Berdine van der Steen, Alex L. Nigg, Meng Chen, Cristina Ivan, Masayoshi Shimizu, Senada Koljenović, Jose A. Hardillo, C. Peter Verrijzer, Robert J. Baatenburg de Jong, George A. Calin, Riccardo Fodde
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-13 (2023)
Abstract Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1; also known as deleted in oral cancer or DOC1) is a tumor suppressor gene known to play functional roles in both cell cycle regulation and in the epigenetic control of embryonic stem ce
Externí odkaz:
https://doaj.org/article/f7824d98a84b4c1d9d47b1294a00ba7e
Autor:
Andrea Sacchetti, Miriam Teeuwssen, Mathijs Verhagen, Rosalie Joosten, Tong Xu, Roberto Stabile, Berdine van der Steen, Martin M Watson, Alem Gusinac, Won Kyu Kim, Inge Ubink, Harmen JG Van de Werken, Arianna Fumagalli, Madelon Paauwe, Jacco Van Rheenen, Owen J Sansom, Onno Kranenburg, Riccardo Fodde
Publikováno v:
eLife, Vol 10 (2021)
Phenotypic plasticity represents the most relevant hallmark of the carcinoma cell as it bestows it with the capacity of transiently altering its morphological and functional features while en route to the metastatic site. However, the study of phenot
Externí odkaz:
https://doaj.org/article/edd28e2414b842c4998587deaa94f069
Autor:
Maria J. De Herdt, Berdine van der Steen, Quincy M. van der Toom, Yassine Aaboubout, Stefan M. Willems, Marjan H. Wieringa, Robert J. Baatenburg de Jong, Leendert H. J. Looijenga, Senada Koljenović, Jose A. Hardillo
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectiveMET positivity is independently associated with survival in oral squamous cell carcinoma (OSCC). Since MET is a known orchestrator of invasive tumor growth, we investigated its association with LNM in early oral tongue squamous cell carcinom
Externí odkaz:
https://doaj.org/article/f8cd03c0fa7a4387b64bf1c90fc11262
Autor:
Yassine Aaboubout, Quincy M. van der Toom, Maria A. J. de Ridder, Maria J. De Herdt, Berdine van der Steen, Cornelia G. F. van Lanschot, Elisa M. Barroso, Maria R. Nunes Soares, Ivo ten Hove, Hetty Mast, Roeland W. H. Smits, Aniel Sewnaik, Dominiek A. Monserez, Stijn Keereweer, Peter J. Caspers, Robert J. Baatenburg de Jong, Tom C. Bakker Schut, Gerwin J. Puppels, José A. Hardillo, Senada Koljenović
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectiveThe depth of invasion (DOI) is considered an independent risk factor for occult lymph node metastasis in oral cavity squamous cell carcinoma (OCSCC). It is used to decide whether an elective neck dissection (END) is indicated in the case of
Externí odkaz:
https://doaj.org/article/747aa41bb148456e9bc6861b26397bd8
Autor:
Maria J. De Herdt, Berdine van der Steen, Robert J. Baatenburg de Jong, Leendert H. J. Looijenga, Senada Koljenović, Jose A. Hardillo
Publikováno v:
Cancers, Vol 14, Iss 6, p 1491 (2022)
The receptor tyrosine kinase MET has gained attention as a therapeutic target. Although MET immunoreactivity is associated with progressive disease, use of targeted therapies has not yet led to major survival benefits. A possible explanation is the l
Externí odkaz:
https://doaj.org/article/de077bf514dd423493cb1a4f58c0ff1b
Autor:
Robert J. Baatenburg de Jong, Senada Koljenović, Berdine van der Steen, C. René Leemans, Daniëlle A.M. Heideman, Ruud H. Brakenhoff, Elisabeth Bloemena, Arjen Brink, Irene Nauta
Publikováno v:
International Journal of Cancer, 149(2), 420-430. Wiley-Liss Inc.
Nauta, I H, Heideman, D A M, Brink, A, van der Steen, B, Bloemena, E, Koljenović, S, Baatenburg de Jong, R J, Leemans, C R & Brakenhoff, R H 2021, ' The unveiled reality of human papillomavirus as risk factor for oral cavity squamous cell carcinoma ', International Journal of Cancer, vol. 149, no. 2, pp. 420-430 . https://doi.org/10.1002/ijc.33514
International Journal of Cancer
International Journal of Cancer, 149(2), 420-430. International Union Against Cancer
Nauta, I H, Heideman, D A M, Brink, A, van der Steen, B, Bloemena, E, Koljenović, S, Baatenburg de Jong, R J, Leemans, C R & Brakenhoff, R H 2021, ' The unveiled reality of human papillomavirus as risk factor for oral cavity squamous cell carcinoma ', International Journal of Cancer, vol. 149, no. 2, pp. 420-430 . https://doi.org/10.1002/ijc.33514
International Journal of Cancer
International Journal of Cancer, 149(2), 420-430. International Union Against Cancer
The prognostic impact of human papillomavirus (HPV) in oropharyngeal cancer is generally acknowledged, and HPV‐status is assessed routinely in clinical practice. Paradoxically, while the oral cavity seems the predilection site for productive HPV‐
Autor:
Evalyn E.A.P. Mulder, Daniëlle Verver, Thom van der Klok, Calvin J. de Wijs, Thierry P.P. van den Bosch, Maria J. De Herdt, Berdine van der Steen, Cornelis Verhoef, Astrid A.M. van der Veldt, Dirk J. Grünhagen, Senada Koljenovic
Publikováno v:
Annals of Diagnostic Pathology, 58:151909. W.B. Saunders
OBJECTIVE: Patients with cutaneous melanoma and a positive sentinel node (SN) are currently eligible for adjuvant treatment with targeted therapy and immune checkpoint inhibitors. Near-infrared (NIR) fluorescence imaging could be an alternative and l
Autor:
Wei Zeng, Leendert H. J. Looijenga, Stefan M. Willems, Ling Liu, Robert J. Baatenburg de Jong, Senada Koljenović, Maria J. De Herdt, Daan Nieboer, Aaron M Gruver, Rob Noorlag, Jose A. Hardillo, Berdine van der Steen
Publikováno v:
Modern Pathology, 33(6), 1015-1032. Nature Publishing Group
Ectodomain shedding unleashes the aggressive nature of the MET oncogene product. Using specific C- and N-terminal MET antibodies (D1C2 and A2H2-3), MET protein status (i.e., no MET, decoy MET, transmembranous C-terminal MET with or without the ectodo
Autor:
Ling Liu, Robert J. Baatenburg de Jong, Maria J. De Herdt, Aaron M Gruver, Stefan M. Willems, Daan Nieboer, Berdine van der Steen, Leendert H. J. Looijenga, Wei Zeng, Marjan H. Wieringa, Senada Koljenović, Jose A. Hardillo
Publikováno v:
Human Pathology, 104, 42-53. W B SAUNDERS CO-ELSEVIER INC
Human Pathology, 104, 42-53. W.B. Saunders
Human Pathology, 104, 42-53. W.B. Saunders
Using tissue microarrays, it was shown that membranous C-terminal MET immunoreactivity and ectodomain (ECD) shedding are associated with poor prognosis in oral cancer. Seen the potential diagnostic value, extrapolation of these results to whole-tissu
Autor:
Arianna Fumagalli, Tong Xu, Roberto Stabile, Harmen J.G. van de Werken, Miriam Teeuwssen, Owen J. Sansom, Rosalie Joosten, Madelon Paauwe, Jacco van Rheenen, Berdine van der Steen, Inge Ubink, Won Kyu Kim, Onno Kranenburg, Andrea Sacchetti, Mathijs Verhagen, Martin M. Watson, Riccardo Fodde, Alem Gusinac
Publikováno v:
eLife
eLife, 10:e61461. eLife Sciences Publications
eLife, Vol 10 (2021)
eLife, 10:e61461. eLife Sciences Publications
eLife, Vol 10 (2021)
Phenotypic plasticity represents the most relevant hallmark of the carcinoma cell as it bestows it with the capacity of transiently altering its morphological and functional features while en route to the metastatic site. However, the study of phenot