Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Beow Keat Yap"'
Autor:
De Chen Chiang, Beow Keat Yap
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 10745-10761 (2024)
Aberrant expression of TRIM proteins has been correlated with poor prognosis and metastasis in many cancers, with many TRIM proteins acting as key oncogenic factors. TRIM proteins are actively involved in many cancer signaling pathways, such as p53,
Externí odkaz:
https://doaj.org/article/6cff73408f3f4dec82e03762c8446a10
Autor:
Ghazi Aljabal, Beow Keat Yap
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1290 (2022)
14-3-3 sigma is a vital negative cell cycle regulator. Its expression is consistently downregulated in many types of cancer through gene promoter hypermethylation or proteasomal degradation. 14-3-3 sigma needs to form a homodimer to be functional, wh
Externí odkaz:
https://doaj.org/article/3b4a4d68369a467cb0016cd3091dcf24
Autor:
Mohammad G. Al-Thiabat, Amirah Mohd Gazzali, Noratiqah Mohtar, Vikneswaran Murugaiyah, Ezatul Ezleen Kamarulzaman, Beow Keat Yap, Noorsaadah Abd Rahman, Rozana Othman, Habibah A. Wahab
Publikováno v:
Molecules, Vol 26, Iss 17, p 5304 (2021)
Drug targeting is a progressive area of research with folate receptor alpha (FRα) receiving significant attention as a biological marker in cancer drug delivery. The binding affinity of folic acid (FA) to the FRα active site provides a basis for re
Externí odkaz:
https://doaj.org/article/02e6aac2213a40c6a540cf25239694ba
Autor:
Mohammad G. Al-Thiabat, Fadi G. Saqallah, Amirah Mohd Gazzali, Noratiqah Mohtar, Beow Keat Yap, Yee Siew Choong, Habibah A Wahab
Publikováno v:
Molecules, Vol 26, Iss 4, p 1079 (2021)
Folate receptor alpha (FRα) is known as a biological marker for many cancers due to its overexpression in cancerous epithelial tissue. The folic acid (FA) binding affinity to the FRα active site provides a basis for designing more specific targets
Externí odkaz:
https://doaj.org/article/a08fd84cf58b4731b2bef61e1d951057
Autor:
Ghazi Aljabal, Beow Keat Yap
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 441 (2020)
14-3-3σ is an acidic homodimer protein with more than one hundred different protein partners associated with oncogenic signaling and cell cycle regulation. This review aims to highlight the crucial role of 14-3-3σ in controlling tumor growth and ap
Externí odkaz:
https://doaj.org/article/e95310b31dc648118435c7006dfe02ea
14-3-3σ protein is one of the seven isoforms from the highly conserved eukaryotic 14-3-3 protein family. Downregulation of 14-3-3σ expression has been observed in various tumors. TRIM25 is responsible for the proteolytic degradation of 14-3-3σ, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adef23cf1c678abe2bd2a51ef158c44
Autor:
Beow Keat Yap, Ghazi Aljabal
Publikováno v:
Pharmaceuticals; Volume 15; Issue 10; Pages: 1290
14-3-3 sigma is a vital negative cell cycle regulator. Its expression is consistently downregulated in many types of cancer through gene promoter hypermethylation or proteasomal degradation. 14-3-3 sigma needs to form a homodimer to be functional, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc7e6df03a55ff5d3e87ff4becc091e
Publikováno v:
Malaysian Journal of Pharmacy. 6:6-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8b9bd536557d813e3a450736ac7e721
https://doi.org/10.52494/qawj8258
https://doi.org/10.52494/qawj8258
Autor:
Vikneswaran Murugaiyah, Rozana Othman, Noorsaadah Abd Rahman, Noratiqah Mohtar, Habibah A. Wahab, Beow Keat Yap, Amirah Mohd Gazzali, Mohammad G Al-Thiabat, Ezatul Ezleen Kamarulzaman
Publikováno v:
Molecules
Volume 26
Issue 17
Molecules, Vol 26, Iss 5304, p 5304 (2021)
Volume 26
Issue 17
Molecules, Vol 26, Iss 5304, p 5304 (2021)
Drug targeting is a progressive area of research with folate receptor alpha (FRα) receiving significant attention as a biological marker in cancer drug delivery. The binding affinity of folic acid (FA) to the FRα active site provides a basis for re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dab7557006f27941710703999e1c42
Autor:
Lay-Harn Gam, Beow Keat Yap
Publikováno v:
Food Chemistry. 274:16-19
Gelatin is commonly used in food supplements and in the form of soft or hard capsules. The source of gelatins is usually from porcine and bovine, and less commonly from vegetable and fish. Nevertheless, these different origins of gelatin have much si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484e3f76ff985fe7de987134d4459a5e
https://doi.org/10.1016/j.foodchem.2018.08.111
https://doi.org/10.1016/j.foodchem.2018.08.111