Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Benzhi Cai"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Arteriovenous fistulas (AVFs) are the most common vascular access points for hemodialysis (HD), but they have a high incidence of postoperative dysfunction, mainly due to excessive neointimal hyperplasia (NIH). Our previous studies have reve
Externí odkaz:
https://doaj.org/article/6a61231c3788488aa2ca4eeb07bf4f7f
Autor:
Wenya Ma, Yanan Tian, Leping Shi, Jing Liang, Qimeng Ouyang, Jianglong Li, Hongyang Chen, Hongyue Sun, Haoyu Ji, Xu Liu, Wei Huang, Xinlu Gao, Xiaoyan Jin, Xiuxiu Wang, Yining Liu, Yang Yu, Xiaofei Guo, Ye Tian, Fan Yang, Faqian Li, Ning Wang, Benzhi Cai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Translational control is crucial for protein production in various biological contexts. Here, we use Ribo-seq and RNA-seq to show that genes related to oxidative phosphorylation are translationally downregulated during heart regeneration. We
Externí odkaz:
https://doaj.org/article/42fb7334384e46d5a6c07d984296926e
Autor:
Changzhu Li, Yang Zhang, Jingling Shen, Hairong Bao, Yue Zhao, Desheng Li, Sijia Li, Yining Liu, Jiming Yang, Zhiwen Zhou, Kangyi Gao, Lexin Zhao, Yao Pei, Yanjie Lu, Zhenwei Pan, Benzhi Cai
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract Cardiomyocyte maturation is the final stage of heart development, and abnormal cardiomyocyte maturation will lead to serious heart diseases. CXXC zinc finger protein 1 (Cfp1), a key epigenetic factor in multi‐lineage cell development, rema
Externí odkaz:
https://doaj.org/article/0a81858492eb4ffe99491a74c358ee28
Autor:
Rui Gong, Xinlu Gao, Yu Liu, Yifu Shen, Zuke Jiang, Xiuxiu Wang, Naufal Zagidullin, Wenya Ma, Ning Wang, Benzhi Cai
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/29773638a3b94b54bf0e757b82fd9283
Autor:
Qi Yu, Benzhi Cai, Yong Zhang, Juan Xu, Dongping Liu, Xiyang Zhang, Zhenbo Han, Yingying Ma, Lei Jiao, Manyu Gong, Xuewen Yang, Yanying Wang, Haodong Li, Lihua Sun, Yu Bian, Fan Yang, Lina Xuan, Haodi Wu, Baofeng Yang, Ying Zhang
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108051- (2023)
Summary: Long non-coding RNAs (lncRNAs) play widespread roles in various processes. However, there is still limited understanding of the precise mechanisms through which they regulate early stage cardiomyocyte differentiation. In this study, we ident
Externí odkaz:
https://doaj.org/article/ff6585f9cd9443f88eaa5482dc9d677c
Autor:
Jiamin Li, Hongru Xue, Ning Xu, Liling Gong, Ming Li, Sijia Li, Di Huang, Qingwei Zhang, Pengyu Li, Qingsui Li, Hang Yu, Yining Liu, Yadong Xue, Haixin Chen, Jiali Liu, Wanyu Zhang, Mingbin Liu, Siyu Chang, Xianzhi Lang, Xingmiao Zhao, Weijie Du, Benzhi Cai, Ning Wang, Baofeng Yang
Publikováno v:
Engineering, Vol 20, Iss , Pp 49-62 (2023)
Myocardial infarction (MI), the most serious of the ischemic heart diseases, is accompanied by myocardial metabolic disorders and the loss of cardiomyocytes. Increasing evidence has shown that long noncoding RNAs (lncRNAs) are involved in various pat
Externí odkaz:
https://doaj.org/article/fd57724fcb9f440889617560b78657b7
Autor:
Yining Liu, Jiamin Li, Ning Xu, Hang Yu, Liling Gong, Qingsui Li, Zhenyu Yang, Sijia Li, Jiming Yang, Di Huang, Yadong Xue, Genlong Xue, Jiali Liu, Haixin Chen, Ruijie Zhang, Anqi Li, Yiming Zhao, PengYu Li, Ming Li, Mingbin Liu, Ning Wang, Benzhi Cai
Publikováno v:
Journal of Advanced Research, Vol 39, Iss , Pp 275-289 (2022)
Introduction: The principal voltage-gated Na+ channel, NaV1.5 governs heart excitability and conduction. NaV1.5 dysregulation is responsible for ventricular arrhythmias and subsequent sudden cardiac death (SCD) in post-infarct hearts. The transcripti
Externí odkaz:
https://doaj.org/article/685ac6dfc55745f19f795c08f1e03501
Autor:
Lukas Fiedler, Lukas J. Motloch, Anna-Maria Dieplinger, Peter Jirak, Paruir Davtyan, Diana Gareeva, Elena Badykova, Marat Badykov, Irina Lakman, Aleksandr Agapitov, Liana Sadikova, Valentin Pavlov, Fabian Föttinger, Moritz Mirna, Kristen Kopp, Uta C. Hoppe, Rudin Pistulli, Benzhi Cai, Baofeng Yang, Naufal Zagidullin
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: While acute Coronavirus disease 2019 (COVID-19) affects the cardiovascular (CV) system according to recent data, an increased CV risk has been reported also during long-term follow-up (FU). In addition to other CV pathologies in COVID-1
Externí odkaz:
https://doaj.org/article/5e2dcd583bcc4eb4b30434008f09491a
Autor:
Zhenbo Han, Zihang Xu, Ying Yu, Yang Cao, Zhengyi Bao, Xinlu Gao, Danyu Ye, Gege Yan, Rui Gong, Juan Xu, Lai Zhang, Wenya Ma, Xiuxiu Wang, Fan Yang, Hong Lei, Ye Tian, Shijun Hu, Djibril Bamba, Ying Li, Desheng Li, Changzhu Li, Ning Wang, Ying Zhang, Zhenwei Pan, Baofeng Yang, Benzhi Cai
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 22-33 (2021)
N6-methyladenosine (m6A), as the most abundant modification of mammalian messenger RNAs, is essential for tissue development and pathogenesis. However, the biological significance of m6A methylation in cardiac differentiation and development remains
Externí odkaz:
https://doaj.org/article/84567e9099184ddf8b22062dfe37de9c
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-19 (2021)
Abstract Cardiovascular diseases such as myocardial infarction (MI) is a major contributor to human mortality and morbidity. The mammalian adult heart almost loses its plasticity to appreciably regenerate new cardiomyocytes after injuries, such as MI
Externí odkaz:
https://doaj.org/article/f4f6a016ec0a47729c04bc850f12b1d0