Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bente Winkler"'
Publikováno v:
Bio-Protocol, Vol 12, Iss 23 (2022)
Pathogen invasion of the central nervous system (CNS) is an important cause of infection-related mortality worldwide and can lead to severe neurological sequelae. To gain access to the CNS cells, pathogens have to overcome the blood–brain barrier (
Externí odkaz:
https://doaj.org/article/c1662a6115b04055b151b869a14a3f67
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The Drosophila nervous system comprises a small number of well characterized glial cell classes. The outer surface of the central nervous system (CNS) is protected by a glial derived blood-brain barrier generated by perineurial and subperineurial gli
Externí odkaz:
https://doaj.org/article/f692871504cc4f279e3b7f14f8da7a32
Autor:
Kerem Yildirim, Bente Winkler, Nicole Pogodalla, Steffi Mackensen, Marie Baldenius, Luis Garcia, Elke Naffin, Silke Rodrigues, Christian Klämbt
Publikováno v:
Biology Open, Vol 11, Iss 1 (2022)
Neuronal processing is energy demanding and relies on sugar metabolism. To nurture the Drosophila nervous system, the blood-brain barrier forming glial cells take up trehalose from the hemolymph and then distribute the metabolic products further to a
Externí odkaz:
https://doaj.org/article/b45f97be6fe74279a76a4b17ede3500c
Autor:
Billel Benmimoun, Dominik Funke, Simone Rey, Bente Winkler, Christian Klämbt, Mary A. Logan, Pauline Spéder
Publikováno v:
Science Advances
Science Advances, 2021, 7 (44), pp.eabh0050. ⟨10.1126/sciadv.abh0050⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (44), pp.eabh0050. ⟨10.1126/sciadv.abh0050⟩
Science Advances, 2021, 7 (44), pp.eabh0050. ⟨10.1126/sciadv.abh0050⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (44), pp.eabh0050. ⟨10.1126/sciadv.abh0050⟩
Description
Macrophages can invade the fly brain triggered by inflammation and show phagocytotic responses reducing longevity.
The nervous system is shielded from circulating immune cells by the blood-brain barrier (BBB). During infections
Macrophages can invade the fly brain triggered by inflammation and show phagocytotic responses reducing longevity.
The nervous system is shielded from circulating immune cells by the blood-brain barrier (BBB). During infections