Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bente Hofstra"'
Autor:
Brennon O’Callaghan, Bente Hofstra, Hillary P. Handler, Holly B. Kordasiewicz, Tracy Cole, Lisa Duvick, Jillian Friedrich, Orion Rainwater, Praseuth Yang, Michael Benneyworth, Tessa Nichols-Meade, Wesley Heal, Rachel Ter Haar, Christine Henzler, Harry T. Orr
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 1006-1016 (2020)
Spinocerebellar ataxia type 1 (SCA1) is a lethal, autosomal dominant neurodegenerative disease caused by a polyglutamine expansion in the ATAXIN-1 (ATXN1) protein. Preclinical studies demonstrate the therapeutic efficacy of approaches that target and
Externí odkaz:
https://doaj.org/article/15f7655d7b4b46cf81aff01299a0c211
As there is growing evidence of shared pathogenesis between Alzheimer’s disease and depression, we aimed to further investigate the shared disease mechanisms of these highly comorbid disorders using brain-specific eQTL data and gene co-expression n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2a931acc5f93f41d150b5294f8e9287
https://doi.org/10.21203/rs.3.rs-2556408/v1
https://doi.org/10.21203/rs.3.rs-2556408/v1
Autor:
Michael A. Benneyworth, Rachel Ter Haar, Holly Kordasiewicz, Jillian Friedrich, Orion Rainwater, Lisa A. Duvick, Wesley Heal, Praseuth Yang, Tessa Nichols-Meade, Tracy Cole, Bente Hofstra, Christine Henzler, Brennon L. O'Callaghan, Hillary P Handler, Harry T. Orr
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 21, Iss, Pp 1006-1016 (2020)
Molecular Therapy: Nucleic Acids, Vol 21, Iss, Pp 1006-1016 (2020)
Spinocerebellar ataxia type 1 (SCA1) is a lethal, autosomal dominant neurodegenerative disease caused by a polyglutamine expansion in the ATAXIN-1 (ATXN1) protein. Preclinical studies demonstrate the therapeutic efficacy of approaches that target and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea4f084766562b635db139631308a91
https://pubmed.ncbi.nlm.nih.gov/32818920
https://pubmed.ncbi.nlm.nih.gov/32818920
Autor:
Brennon L. O'Callaghan, Zhao Chen, Harry T. Orr, H. Brent Clark, Holly B. Kordasiewicz, Bente Hofstra, Tessa Nichols-Meade, Hillary P Handler, Jillian Friedrich, Eric E. Swayze, Gülin Öz, Lisa A. Duvick, Michael A. Benneyworth, Carmen Wagener, Christine Henzler, Sarah N. Larson, Judit M. Pérez Ortiz, Huda Y. Zoghbi, Orion Rainwater, Praseuth Yang
Publikováno v:
JCI Insight. 3
Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited ataxia caused by expansion of a translated CAG repeat encoding a glutamine tract in the ataxin-1 (ATXN1) protein. Despite advances in understanding the pathogenesis of SCA1, there are sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63165077c86ce3d5b6b369a097aad187
https://doi.org/10.1172/jci.insight.123193
https://doi.org/10.1172/jci.insight.123193