Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Bente, Kiens"'
Autor:
Ye Cao, Masaya Araki, Yoshimi Nakagawa, Luisa Deisen, Annemarie Lundsgaard, Josephine M. Kanta, Stephanie Holm, Kornelia Johann, Jens Christian Brings Jacobsen, Markus Jähnert, Annette Schürmann, Bente Kiens, Christoffer Clemmensen, Hitoshi Shimano, Andreas M. Fritzen, Maximilian Kleinert
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101991- (2024)
Objective: Dietary medium-chain fatty acids (MCFAs), characterized by chain lengths of 8–12 carbon atoms, have been proposed to have beneficial effects on glucose and lipid metabolism, yet the underlying mechanisms remain elusive. We hypothesized t
Externí odkaz:
https://doaj.org/article/a73423385e39458e84871af2e20ee693
Acyl‐CoA synthetase expression in human skeletal muscle is reduced in obesity and insulin resistance
Autor:
Margarete Poppelreuther, Anne‐Marie Lundsgaard, Pernille Mensberg, Kim Sjøberg, Tina Vilsbøll, Bente Kiens, Joachim Füllekrug
Publikováno v:
Physiological Reports, Vol 11, Iss 18, Pp n/a-n/a (2023)
Abstract Upon intramuscular entry, fatty acids are converted to amphiphatic fatty acyl‐CoAs by action of the acyl‐CoA synthetase (ACS) enzymes. While it has been reported that insulin resistant skeletal muscle shows an accumulation of fatty acyl
Externí odkaz:
https://doaj.org/article/6a0a4a12c6464808912a29c001f6bcab
Autor:
Josephine M. Kanta, Luisa Deisen, Kornelia Johann, Stephanie Holm, Annemarie Lundsgaard, Jens Lund, Markus Jähnert, Annette Schürmann, Christoffer Clemmensen, Bente Kiens, Andreas M. Fritzen, Maximilian Kleinert
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101760- (2023)
Objective: Medium chain fatty acids (MCFAs), which are fatty acids with chain lengths of 8–12 carbon atoms, have been shown to reduce food intake in rodents and humans, but the underlying mechanisms are unknown. Unlike most other fatty acids, MCFAs
Externí odkaz:
https://doaj.org/article/5dd29cdca916406fad79610195385845
Autor:
Aslak Emil Lyster, Solvejg Lis Hansen, Christina Therese Andersen, Jens Bo Nielsen, Klaas Westerterp, Loek Wouters, Bente Kiens, Anina Ritterband-Rosenbaum
Publikováno v:
Nutrients, Vol 15, Iss 24, p 5042 (2023)
Adults with severe cerebral palsy (CP) are susceptible to malnutrition and metabolic disorders due to limited daily physical activity and challenges related to eating. We hypothesized that the condition of being underweight arises from inadequate ene
Externí odkaz:
https://doaj.org/article/2751e25799fb4c6099f62a17d6ba5061
Autor:
Anders B. Klein, Trine S. Nicolaisen, Niels Ørtenblad, Kasper D. Gejl, Rasmus Jensen, Andreas M. Fritzen, Emil L. Larsen, Kristian Karstoft, Henrik E. Poulsen, Thomas Morville, Ronni E. Sahl, Jørn W. Helge, Jens Lund, Sarah Falk, Mark Lyngbæk, Helga Ellingsgaard, Bente K. Pedersen, Wei Lu, Brian Finan, Sebastian B. Jørgensen, Randy J. Seeley, Maximilian Kleinert, Bente Kiens, Erik A. Richter, Christoffer Clemmensen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The physiological role of GDF15 remains poorly defined. Here, the authors show that circulating GDF15 increases in response to prolonged exercise, but that this exercise-induced GDF15, unlike pharmacological GDF15, does not affect post-exercise food
Externí odkaz:
https://doaj.org/article/8f1d9eea4091471ca84ea46086fb7636
Autor:
Yann W. Yap, Patricia M. Rusu, Andrea Y. Chan, Barbara C. Fam, Andreas Jungmann, Samantha M. Solon-Biet, Christopher K. Barlow, Darren J. Creek, Cheng Huang, Ralf B. Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew D. W. Piper, Mathias Heikenwälder, Stephen J. Simpson, Stefan Bröer, Sofianos Andrikopoulos, Oliver J. Müller, Adam J. Rose
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Dietary protein dilution, where protein is reduced and replaced by other nutrient sources without caloric restriction, promotes metabolic health via the hepatokine Fgf21. Here, the authors show that essential amino acids threonine and tryptophan are
Externí odkaz:
https://doaj.org/article/36856bb21e41464a998b62244a235694
Autor:
Anne-Marie Lundsgaard, Andreas M. Fritzen, Trine S. Nicolaisen, Christian S. Carl, Kim A. Sjøberg, Steffen H. Raun, Anders B. Klein, Eva Sanchez-Quant, Jakob Langer, Cathrine Ørskov, Christoffer Clemmensen, Matthias H. Tschöp, Erik A. Richter, Bente Kiens, Maximilian Kleinert
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 1, Pp 10-19 (2020)
Excessive circulating FAs have been proposed to promote insulin resistance (IR) of glucose metabolism by increasing the oxidation of FAs over glucose. Therefore, inhibition of FA oxidation (FAOX) has been suggested to ameliorate IR. However, prolonge
Externí odkaz:
https://doaj.org/article/d93f2afb21af4c3f990999f0bf005ed4
Autor:
Cecilie Hundahl, Petra Kotzbeck, Hayley B. Burm, Søren H. Christiansen, Lola Torz, Aske W. Helge, Martin P. Madsen, Cecilia Ratner, Annette K. Serup, Jonatan J. Thompson, Thomas O. Eichmann, Tune H. Pers, David P.D. Woldbye, Daniele Piomelli, Bente Kiens, Rudolf Zechner, Louise J. Skov, Birgitte Holst
Publikováno v:
Molecular Metabolism, Vol 47, Iss , Pp 101174- (2021)
Objective: The goal of this study was to investigate the importance of central hormone-sensitive lipase (HSL) expression in the regulation of food intake and body weight in mice to clarify whether intracellular lipolysis in the mammalian hypothalamus
Externí odkaz:
https://doaj.org/article/b4e606e56133422d9a7ea2b947c8d458
Autor:
Jonas R. Knudsen, Dorte E. Steenberg, Janne R. Hingst, Lorna R. Hodgson, Carlos Henriquez-Olguin, Zhencheng Li, Bente Kiens, Erik A. Richter, Jørgen F.P. Wojtaszewski, Paul Verkade, Thomas E. Jensen
Publikováno v:
Molecular Metabolism, Vol 39, Iss , Pp - (2020)
Objective: Exercise is a cornerstone in the management of skeletal muscle insulin-resistance. A well-established benefit of a single bout of exercise is increased insulin sensitivity for hours post-exercise in the previously exercised musculature. Al
Externí odkaz:
https://doaj.org/article/6f85458e27874852be1ceb0f9f6bc40a
Autor:
Andreas Mæchel Fritzen, Joan Domingo-Espín, Anne-Marie Lundsgaard, Maximilian Kleinert, Ida Israelsen, Christian S. Carl, Trine S. Nicolaisen, Rasmus Kjøbsted, Jacob F. Jeppesen, Jørgen F.P. Wojtaszewski, Jens O. Lagerstedt, Bente Kiens
Publikováno v:
Molecular Metabolism, Vol 35, Iss , Pp - (2020)
Objective: Acute administration of the main protein component of high-density lipoprotein, apolipoprotein A-I (ApoA-1), improves glucose uptake in skeletal muscle. The molecular mechanisms mediating this are not known, but in muscle cell cultures, Ap
Externí odkaz:
https://doaj.org/article/e7375ff2f5d843a68500a32a5a557945