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of 41
pro vyhledávání: '"Bent Rubin"'
Autor:
Bent Rubin, M. Høier-Madsen
Publikováno v:
Acta Pathologica Microbiologica Scandinavica Section C Immunology. :429-438
The in vitro proliferative responses of mouse thymus- and spleen cells against the mitogens phytohaemagglutinin (PHA), concanavalin A (Con A) or lipopolysaccharide (LPS) were determined after either 1) anti-θ antiserum and complement, or 2) immunoad
Autor:
Bent Rubin, M. Høoier-Madsen
Publikováno v:
Acta Pathologica Microbiologica Scandinavica Section C Immunology. :267-276
The results of the present experiments have shown that activated thymocyte populations are endowed with a cytotoxic potential against antibody-coated target cells. The effector cells could be divided into at least two subpopulations. 1) host-derived
Autor:
Bent Rubin
Publikováno v:
Acta Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology. :297-304
In the present experiments AKR mice were challenged with 4 × 106 and 4 × 108 SRBC and rechallenged with the same two antigen doses after 10, 30 and 90 days. Maximum primary 19S and 7S PFC responses to 4 × 106 SRBC were achieved on day 5 following
Autor:
Bent Rubin, Lotte Trier
Publikováno v:
Acta Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology. :724-732
Lethally irradiated mice reconstituted with allogeneic bone marrow cells usually survive the irradiation damage, but their immune-status is not completely restored. Thus, such mice show depressed humoral antibody responses to thymus dependent antigen
Publikováno v:
European Journal of Immunology. 23:487-493
T cell antigen receptor (TcR) heterodimers of both the Ti-alpha beta and Ti-gamma delta types are expressed at the surface of T cells noncovalently associated with the CD3 complex composed of the monomorphic chains gamma, delta, epsilon and zeta. The
Autor:
Bent, Rubin, Jean Edouard, Gairin
Publikováno v:
Current topics in microbiology and immunology. 344
In this chapter, a detailed description of how the innate and adaptive immune responses interact with malignant cells is presented. In addition, we discuss how developing tumors establish themselves, and how they benefit on one hand and organize thei
Publikováno v:
Scandinavian Journal of Immunology. 32:731-735
The human Sezary T-cell leukaemia line, HUT.78, represents a population of activated T cells, i.e. they are HLA-DR+ and IL-2R+. We have analysed the capacity of HUT.78 cells (1) to stimulate HLA-DR-specific T-cell lines or clones and (2) to be induce
Publikováno v:
University of Copenhagen
An antigen-specific T-cell line which transforms into T-lymphoma cells in vitro but apparently not in vivo is described. Membrane markers, tumorigenicity and T-cell receptor (TcR) V alpha and V beta-gene usage of the in vitro transformed T-cell line
Publikováno v:
Cellular Immunology. 126:196-210
The present work demonstrates that antibody-induced cross-linking of MHC class I antigens on Jurkat T lymphoma cells leads to a rise in intracellular calcium (Cai2+) and, in the presence of phorbol ester (PMA), to IL-2 production and IL-2 receptor ex