Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Bent H. Havsteen"'
Autor:
Francisco Garcia-Molina, Manuela García-Moreno, F. García-Cánovas, Ramón Varón, R.G. Ladrón-de Guevara, D. Valera-Ruipérez, J. Masiá-Pérez, Bent H. Havsteen
Publikováno v:
Journal of Theoretical Biology. 242:743-754
Starting from a simple general reaction mechanism of activation of aspartic proteinase zymogens involving an uni- and a bimolecular simultaneous route, the time course equation of the concentration of the zymogen and of the activated enzyme have been
Autor:
Ramón Varón, F. García-Cánovas, J. M. Yago, Bent H. Havsteen, Manuela García-Moreno, C. Garrido-Del Solo
Publikováno v:
Applied Mathematics and Computation. 171:450-463
A kinetic analysis is made of an enzymatic reaction with slow-binding inhibition in which the enzyme-substrate complex suffers an irreversible inactivation. The explicite equation for the product of reaction is obtained by solving the system of diffe
Autor:
Manuela García-Moreno, J. M. Yago, F. García-Cánovas, Ramón Varón, Bent H. Havsteen, C. Garrido-Del Solo
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 20:309-316
We present a kinetic study of an enzyme reaction that takes place with slow-binding inhibition where the immediate product undergoes a spontaneous or induced process of decomposition. A kinetic study of an enzyme process, in which a slow-binding inhi
Autor:
Bent H. Havsteen
Publikováno v:
Journal of Theoretical Biology. 231:39-48
The molecular vibrations of the infectious part of the prion protein has been studied by the methods of nonlinear dynamics using NMR-data of the protein in solution to test a new hypothesis for the nature of the pathogenic isomerization. The result w
Autor:
Manuela García-Moreno, M.J. García-Meseguer, Bent H. Havsteen, J. A. Vidal De Labra, Ramón Varón, F. García-Cánovas
Publikováno v:
Bulletin of Mathematical Biology. 65:279-308
A complete analysis has been performed of the mean residence times in linear compartmental systems, closed or open, with or without traps and with zero input. This analysis allows the derivation of explicit and simple general symbolic formulae to obt
Autor:
Bent H. Havsteen
Publikováno v:
European Biophysics Journal. 31:549-553
The diffusion of molecular oxygen or its isosteric analogue, carbon monoxide, from the surface of myoglobin to its deeply imbedded haem appears to represent one of the simplest protein functions. Hence, it was chosen for the study of the possible rol
Autor:
Bent H. Havsteen
Publikováno v:
Pharmacology & Therapeutics. 96:67-202
Flavonoids are plant pigments that are synthesised from phenylalanine, generally display marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are excited by UV light, and are ubiquitous to green plant cells. The fla
Autor:
Ramón Varón, F. García-Cánovas, Manuela García-Moreno, J. A. Vidal De Labra, M.J. García-Meseguer, Bent H. Havsteen
Publikováno v:
Biosystems. 59:197-220
In this contribution, we present the symbolic time course equations corresponding to a general model of a linear compartmental system, closed or open, with or without traps and with zero input. The steady state equations are obtained easily from the
Publikováno v:
Biosystems. 51:169-180
In this paper we present a general kinetic study of slow-binding inhibition processes, i.e. enzyme reactions that do not respond instantly to the presence of a competitive inhibitor. The analysis that we present is based on the equation that describe
Autor:
Bent H. Havsteen, C. Garrido-Del Solo, Francisco García-Sevilla, F. García-Cánovas, Ramón Varón, M.M. Ruiz-Galea, Manuela García-Moreno
Publikováno v:
Biosystems. 50:99-126
In this contribution, we present the derivation, from the strict transient phase equations of enzyme reactions, of the transient phase equations under the usual assumptions that one or more of the reversible steps involved in the mechanism of the enz