Lactoferrin and lysozyme to promote nutritional, clinical and enteric recovery: a protocol for a factorial, blinded, placebo-controlled randomised trial among children with diarrhoea and malnutrition (the Boresha Afya trial)

Autor: Jie Liu, Grace John-Stewart, Barbra A Richardson, Indi Trehan, Ruchi Tiwari, Kirkby D Tickell, Mareme M Diakhate, Benson O Singa, Christine J McGrath, Patricia B Pavlinac, Doreen Rwigi, Judd L Walson, James A Platts-Mills, Eric R Houpt, Arianna Rubin Means, Churchil Nyabinda, Emily Yoshioka, Joyce Otieno, Adeel Shah, Lucia Keter, Maureen Okello, James M Njunge, Julius Nyaoke, Eric Ochola

Publikováno v: BMJ Open, Vol 14, Iss 8 (2024)

Introduction Children with moderate or severe wasting are at particularly high risk of recurrent or persistent diarrhoea, nutritional deterioration and death following a diarrhoeal episode. Lactoferrin and lysozyme are nutritional supplements that ma

Externí odkaz: https://doaj.org/article/60913dbef5ad48deb7fecd92c785d7c4

Antimicrobial resistance including Extended Spectrum Beta Lactamases (ESBL) among E. coli isolated from kenyan children at hospital discharge.

Autor: Stephanie N Tornberg-Belanger, Doreen Rwigi, Michael Mugo, Lynnete Kitheka, Nancy Onamu, Derrick Ounga, Mame M Diakhate, Hannah E Atlas, Anna Wald, R Scott McClelland, Olusegun O Soge, Kirkby D Tickell, Samuel Kariuki, Benson O Singa, Judd L Walson, Patricia B Pavlinac

Publikováno v: PLoS Neglected Tropical Diseases, Vol 16, Iss 3, p e0010283 (2022)

BackgroundChildren who have been discharged from hospital in sub-Saharan Africa remain at substantial risk of mortality in the post-discharge period. Antimicrobial resistance (AMR) may be an important factor. We sought to determine the prevalence and

Externí odkaz: https://doaj.org/article/1d50ebe174874322a84574ba4e949bd6

Impact of a two-way short message service (SMS) to support maternally administered childhood mid-upper arm circumference monitoring and expand malnutrition screening in Kenya: the Mama Aweza trial protocol

Autor: Jennifer A Unger, Barbra A Richardson, Kirkby D Tickell, Mareme M Diakhate, Jeanne L Goodman, Keshet Ronen, Carol Levin, Esther M Choo, Catherine Achieng, Mary Masheti, Benson O Singa, Christine J McGrath

Publikováno v: BMJ Open, Vol 10, Iss 9 (2020)

Introduction Over 52 million children under 5 years of age become wasted each year, but only 17% of these children receive treatment. Novel methods to identify and deliver treatment to malnourished children are necessary to achieve the sustainable de

Externí odkaz: https://doaj.org/article/60db170f8fd14f908d7fa88bbfb3bffc

Enteric Permeability, Systemic Inflammation, and Post-Discharge Growth Among a Cohort of Hospitalized Children in Kenya and Pakistan

Autor: Kirkby D, Tickell, Donna M, Denno, Ali, Saleem, Asad, Ali, Zaubina, Kazi, Benson O, Singa, Catherine, Otieno, Charles, Mutinda, Victor, Ochuodho, Barbra A, Richardson, Kristjana H, Ásbjörnsdóttir, Stephen E, Hawes, James A, Berkley, Judd L, Walson

Publikováno v: Journal of Pediatric Gastroenterology & Nutrition. 75:768-774

To determine whether gut permeability is associated with post-discharge growth and systemic inflammation among hospitalized children in low- and middle-income countries.Children aged 2-23 months being discharged from Civil Hospital Karachi (Pakistan)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef57b68b05fb814a817977ea021a3b1
https://doi.org/10.1097/mpg.0000000000003619

Childhood mortality during and after acute illness in Africa and south Asia

Autor: Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid, Ali Fazal Khan, Ali Faisal Saleem, Benson O Singa, Blaise Siezanga Gnoumou, Caroline Tigoi, Catherine Achieng Otieno, Celine Bourdon, Chris Odhiambo Oduol, Christina L Lancioni, Christine Manyasi, Christine J McGrath, Christopher Maronga, Christopher Lwanga, Daniella Brals, Dilruba Ahmed, Dinesh Mondal, Donna M Denno, Dorothy I Mangale, Emmanuel Chimezi, Emmie Mbale, Ezekiel Mupere, Gazi Md. Salauddin Mamun, Issaka Ouedraogo, James A Berkley, Jenala Njirammadzi, John Mukisa, Johnstone Thitiri, Joseph D Carreon, Judd L Walson, Julie Jemutai, Kirkby D Tickell, Lubaba Shahrin, MacPherson Mallewa, Md. Iqbal Hossain, Mohammod Jobayer Chisti, Molly Timbwa, Moses Mburu, Moses M Ngari, Narshion Ngao, Peace Aber, Philliness Prisca Harawa, Priya Sukhtankar, Robert H J Bandsma, Roseline Maimouna Bamouni, Sassy Molyneux, Shalton Mwaringa, Shamsun Nahar Shaima, Syed Asad Ali, Syeda Momena Afsana, Syera Banu, Tahmeed Ahmed, Wieger P Voskuijl, Zaubina Kazi

Publikováno v: The Lancet Global Health, 10(5), e673-e684. Elsevier BV
Diallo, A H, Sayeem Bin Shahid, A S M, Khan, A F, Saleem, A F, Singa, B O, Gnoumou, B S, Tigoi, C, Otieno, C A, Bourdon, C, Oduol, C O, Lancioni, C L, Manyasi, C, McGrath, C J, Maronga, C, Lwanga, C, Brals, D, Ahmed, D, Mondal, D, Denno, D M, Mangale, D I, Chimezi, E, Mbale, E, Mupere, E, Mamun, G M S, Ouedraogo, I, Berkley, J A, Njirammadzi, J, Mukisa, J, Thitiri, J, Carreon, J D, Walson, J L, Jemutai, J, Tickell, K D, Shahrin, L, Mallewa, M, Hossain, M I, Chisti, M J, Timbwa, M, Mburu, M, Ngari, M M, Ngao, N, Aber, P, Harawa, P P, Sukhtankar, P, Bandsma, R H J, Bamouni, R M, Molyneux, S, Mwaringa, S, Shaima, S N, Ali, S A, Afsana, S M, Banu, S, Ahmed, T, Voskuijl, W P, Kazi, Z & The Childhood Acute Illness and Nutrition (CHAIN) Network 2022, ' Childhood mortality during and after acute illness in Africa and south Asia : a prospective cohort study ', The Lancet Global Health, vol. 10, no. 5, pp. e673-e684 . https://doi.org/10.1016/S2214-109X(22)00118-8
lancet global health, 10(5), e673-e684. Elsevier BV

Background Mortality among children with acute illness in low-income and middle-income settings remains unacceptably high and the importance of post-discharge mortality is increasingly recognised. We aimed to explore the epidemiology of deaths among

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d25d0b393e7f5108a459a3b299d763a
http://www.scopus.com/inward/record.url?scp=85127917116&partnerID=8YFLogxK