Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Benoit deCrombrugghe"'
Autor:
Jung Park, Matthias Gebhardt, Svitlana Golovchenko, Francesc Perez-Branguli, Takako Hattori, Christine Hartmann, Xin Zhou, Benoit deCrombrugghe, Michael Stock, Holm Schneider, Klaus von der Mark
Publikováno v:
Biology Open, Vol 4, Iss 5, Pp 608-621 (2015)
According to the general understanding, the chondrocyte lineage terminates with the elimination of late hypertrophic cells by apoptosis in the growth plate. However, recent cell tracking studies have shown that murine hypertrophic chondrocytes can su
Externí odkaz:
https://doaj.org/article/e2798622190b474cb08d9c471dbfacbb
Autor:
Bin Yuan, Qi Zhang, Benoit deCrombrugghe, Anudishi Tyagi, Xin Zhou, Fouad El-Dana, Michael Andreeff, Marina Konopleva, Venkata Lokesh Battula, Stanley Ly, Behrang Amini, Christine B. Peterson, Vinitha Mary Kuruvilla
Publikováno v:
Blood. 136:27-27
Background: Genetic alterations in the osteoprogenitor cells has been shown to induce acute myeloid leukemia (AML) in several mouse models. Moreover, we have recently reported that AML cells induce osteogenic differentiation in mesenchymal stromal ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab20f0d346d76e54b5d4b61ce9e85ce
https://doi.org/10.1182/blood-2020-142777
https://doi.org/10.1182/blood-2020-142777
Autor:
Marina Konopleva, Michael Andreeff, Anudishi Tyagi, Benoit deCrombrugghe, Venkata Lokesh Battula, Stanley Ly, Bin Yuan, Xin Zhou, Vinitha Mary Kuruvilla, Qi Zhang, Fouad El-Dana
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 20:S195
Context We have reported that AML cells induce osteogenic differentiation in MSCs to facilitate AML growth in the bone marrow (BM) (Battula et al. JCI Insight, 2017). However, the effect of AML cells on various osteo-lineage cells in the BM microenvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7227e2df17da247dc6a12f0467b3838a
https://doi.org/10.1016/s2152-2650(20)30740-0
https://doi.org/10.1016/s2152-2650(20)30740-0
Autor:
Yu Chen Lee, Guoyu Yu, Christopher J. Logothetis, Monzur Murshed, Li Yuan Yu-Lee, Laura Baseler, Sue Hwa Lin, Chien Jui Cheng, Keigi Fujiwara, Sankar N. Maity, Jun Ichi Abe, Gary E. Gallick, Nhat Tu Le, Khoi Chu, Song Chang Lin, Xin Zhou, Benoit deCrombrugghe
Prostate cancer (PCa) bone metastasis is frequently associated with bone-forming lesions, but the source of the osteoblastic lesions remains unclear. We show that the tumor-induced bone derives partly from tumor-associated endothelial cells that have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9bc3cbc8f96635fb6cbd087dc4c9ab
https://europepmc.org/articles/PMC5512590/
https://europepmc.org/articles/PMC5512590/
Publikováno v:
Journal of Bone and Mineral Research. 29:855-865
Commitment of Runx2-expressing precursor osteoblasts to functional osteoblasts and then to osteocytes is triggered by Osterix (Osx), which activates its target genes in those cells during bone formation. It is not yet known whether Osx has a role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af66ca1b644752b2810324a0c92d751f
https://doi.org/10.1002/jbmr.2103
https://doi.org/10.1002/jbmr.2103
Autor:
Bin Yuan, Stanley Ly, Venkata Lokesh Battula, Vivien Tran, Khoa Nguyen, Michael Andreeff, Jared K. Burks, Benoit deCrombrugghe, Kiersten L. Maldonado, Xin Zhou, Charles Kinglsey
Publikováno v:
Blood. 132:86-86
Acute myeloid leukemia (AML) is one of the most aggressive hematological malignancy that originates in the bone marrow (BM). Despite advances in the molecular characterization of AML, factors regulating its progression are still not known. Among seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3fa1ff8cc8037ee7f2c0ecc9b535ac
https://doi.org/10.1182/blood-2018-99-117258
https://doi.org/10.1182/blood-2018-99-117258
Autor:
Yu Chen Lee, Benoit deCrombrugghe, Chih-Fen Huang, Gary E. Gallick, Monzur Murshed, Li-Yuan Yu-Lee, Sue-Hwa Lin, Khoi Chu, Xiangcang Ye, John C. Araujo
Publikováno v:
Oncogene. 29:3196-3207
Dasatinib, a dual Src family kinase and Abl inhibitor, is being tested clinically for the treatment of prostate cancer bone metastasis. Bidirectional interactions between osteoblasts and prostate cancer cells are critical in the progression of prosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af182a5b4b0adad644d0281b39b9ba7
https://doi.org/10.1038/onc.2010.73
https://doi.org/10.1038/onc.2010.73
Autor:
Heidi Eberspaecher, Gerald J. Pinero, Magnus Höök, Tamayuki Shinomura, Benoit deCrombrugghe, Jan Johnson
Publikováno v:
Developmental Dynamics. 216:499-510
We have examined the expression pattern of the PG-Lb/epiphycan gene that encodes a small leucine-rich repeat proteoglycan during mouse embryonic development. PG-Lb/epiphycan mRNA transcripts were first detected at E12.5 days postcoitus (dpc) at high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::797d6ff0eb23bdadca9e0db6905473b0
https://doi.org/10.1002/(sici)1097-0177(199912)216:4/5<499::aid-dvdy18>3.0.co
https://doi.org/10.1002/(sici)1097-0177(199912)216:4/5<499::aid-dvdy18>3.0.co
Publikováno v:
Proceedings of the National Academy of Sciences. 66:480-487
A cyclic AMP binding protein has been purified over 100-fold from E. coli extracts. Protein purified from wild-type strains binds cyclic AMP with an apparent dissociation constant of 1-2 × 10 -6 M . Two mutant strains that are unresponsive to exogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eef871e3710a9af89720607c3f8c923
https://doi.org/10.1073/pnas.66.2.480
https://doi.org/10.1073/pnas.66.2.480
Autor:
Michael Emmer, Beatrice Chen, Robert L. Perlman, Ira Pastan, Benoit deCrombrugghe, Harold E. Varmus, Max Gottesman
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 35:419-423
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eff5c911cac5e0080881fc4e7fe02ff1
https://doi.org/10.1101/sqb.1970.035.01.054
https://doi.org/10.1101/sqb.1970.035.01.054