Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Benoit Pourcet"'
Autor:
Marie Bobowski-Gerard, Clémence Boulet, Francesco P. Zummo, Julie Dubois-Chevalier, Céline Gheeraert, Mohamed Bou Saleh, Jean-Marc Strub, Amaury Farce, Maheul Ploton, Loïc Guille, Jimmy Vandel, Antonino Bongiovanni, Ninon Very, Eloïse Woitrain, Audrey Deprince, Fanny Lalloyer, Eric Bauge, Lise Ferri, Line-Carolle Ntandja-Wandji, Alexia K. Cotte, Corinne Grangette, Emmanuelle Vallez, Sarah Cianférani, Violeta Raverdy, Robert Caiazzo, Viviane Gnemmi, Emmanuelle Leteurtre, Benoit Pourcet, Réjane Paumelle, Kim Ravnskjaer, Guillaume Lassailly, Joel T. Haas, Philippe Mathurin, François Pattou, Laurent Dubuquoy, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Myofibroblasts contribute to the development of liver fibrosis. Here, the authors report that the transcription factor Basonuclin 2 (BNC2) integrates fibrogenic signals and drives myofibroblastic transcriptional activation in liver fibrosis.
Externí odkaz:
https://doaj.org/article/c0d2d56ec91641b79809fad780054395
Autor:
Alexis Boulinguiez, Christian Duhem, Alicia Mayeuf-Louchart, Benoit Pourcet, Yasmine Sebti, Kateryna Kondratska, Valérie Montel, Stéphane Delhaye, Quentin Thorel, Justine Beauchamp, Aurore Hebras, Marion Gimenez, Marie Couvelaere, Mathilde Zecchin, Lise Ferri, Natalia Prevarskaya, Anne Forand, Christel Gentil, Jessica Ohana, France Piétri-Rouxel, Bruno Bastide, Bart Staels, Helene Duez, Steve Lancel
Publikováno v:
JCI Insight, Vol 7, Iss 17 (2022)
The sarcoplasmic reticulum (SR) plays an important role in calcium homeostasis. SR calcium mishandling is described in pathological conditions, such as myopathies. Here, we investigated whether the nuclear receptor subfamily 1 group D member (NR1D1,
Externí odkaz:
https://doaj.org/article/d7d19994c75c40799391c0482220b435
Autor:
Marina Gomes Machado, Thiago Andrade Patente, Yves Rouillé, Severine Heumel, Eliza Mathias Melo, Lucie Deruyter, Benoit Pourcet, Valentin Sencio, Mauro Martins Teixeira, François Trottein
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Short-chain fatty acids (SCFAs) are metabolites produced mainly by the gut microbiota with a known role in immune regulation. Acetate, the major SCFA, is described to disseminate to distal organs such as lungs where it can arm sentinel cells, includi
Externí odkaz:
https://doaj.org/article/ff37ccf19a714dd190ff3c7d14bde444
Autor:
Hélène Duez, Benoit Pourcet
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
The innate immune system is the first line of defense specialized in the clearing of invaders whether foreign elements like microbes or self-elements that accumulate abnormally including cellular debris. Inflammasomes are master regulators of the inn
Externí odkaz:
https://doaj.org/article/e1775686ff9c439b9cee7d97c59a3f60
Autor:
Benoit Pourcet, Hélène Duez
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The innate immune system senses “non-self” molecules derived from pathogens (PAMPs) as well as endogenous damage-associated molecular patterns (DAMPs) and promotes sterile inflammation that is necessary for injury resolution, tissue repair/regene
Externí odkaz:
https://doaj.org/article/0ccdcc7fc9244462a6c0df9ac038456e
Autor:
Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Stéphane Delhaye, Christian Duhem, Justine Beauchamp, Lise Ferri, Quentin Thorel, Alexis Boulinguiez, Mathilde Zecchin, Julie Dubois-Chevalier, Jérôme Eeckhoute, Logan T. Vaughn, Peter J. Roach, Christian Dani, Bartholomew A. Pederson, Stéphane D. Vincent, Bart Staels, Hélène Duez
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1410-1418.e6 (2019)
Summary: Browning induction or transplantation of brown adipose tissue (BAT) or brown/beige adipocytes derived from progenitor or induced pluripotent stem cells (iPSCs) can represent a powerful strategy to treat metabolic diseases. However, our poor
Externí odkaz:
https://doaj.org/article/00e94624b982459bb752e5e8a93046f6
Autor:
Jean-Sébastien Annicotte, Patrick Collombat, Amélie Bonnefond, Benoit Pourcet, Philippe Froguel, François Pattou, Julie Kerr-Conte, Lluis Fajas, Patrick Meffre, Zohra Benfodda, Pierre-Damien Denechaud, Sarah Anissa Hannou, Etienne Blanc, Mehdi Derhourhi, Lionel Berberian, Souhila Amanzougarene, Emmanuelle Durand, Nabil Rabhi, Charlène Carney, Maeva Moreno, Xavier Gromada, Laure Rolland, Emilie Courty, Marika Elsa Friano, Cyril Bourouh, Frédérik Oger
The loss of pancreatic β-cell identity emerges as an important feature of type 2 diabetes development, but the molecular mechanisms are still elusive. Here, we explore the cell-autonomous role of the cell cycle regulator and transcription factor E2F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8b941ef57b5273737f441d7144efa3
https://doi.org/10.2337/figshare.22906517.v1
https://doi.org/10.2337/figshare.22906517.v1
Autor:
Frédérik Oger, Cyril Bourouh, Marika Elsa Friano, Emilie Courty, Laure Rolland, Xavier Gromada, Maeva Moreno, Charlène Carney, Nabil Rabhi, Emmanuelle Durand, Souhila Amanzougarene, Lionel Berberian, Mehdi Derhourhi, Etienne Blanc, Sarah Anissa Hannou, Pierre-Damien Denechaud, Zohra Benfodda, Patrick Meffre, Lluis Fajas, Julie Kerr-Conte, François Pattou, Philippe Froguel, Benoit Pourcet, Amélie Bonnefond, Patrick Collombat, Jean-Sébastien Annicotte
Publikováno v:
Diabetes.
The loss of pancreatic β-cell identity emerges as an important feature of type 2 diabetes development, but the molecular mechanisms are still elusive. Here, we explore the cellautonomous role of the cell cycle regulator and transcription factor E2F1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44d92b613ace2d469b2c6959b2f0931f
https://doi.org/10.2337/db22-0604
https://doi.org/10.2337/db22-0604
Autor:
Hélène Duez, Benoit Pourcet
Publikováno v:
médecine/sciences
médecine/sciences, 2022, 38 (8-9), pp.669-678. ⟨10.1051/medsci/2022102⟩
médecine/sciences, 2022, 38 (8-9), pp.669-678. ⟨10.1051/medsci/2022102⟩
The biological clock is a set of evolutionarily conserved "clock proteins" that generate circadian rhythms in behavior and physiological processes. The clock programs these processes at specific times of the day, allowing the organism to optimize its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea1bc6738c739cdcd2ddabd34f6aa1b
https://hal.science/hal-03778841/document
https://hal.science/hal-03778841/document
Autor:
Hélène, Duez, Benoit, Pourcet
Publikováno v:
médecine/sciences
médecine/sciences, 2022, 38 (8-9), pp.669-678. ⟨10.1051/medsci/2022102⟩
médecine/sciences, 2022, 38 (8-9), pp.669-678. ⟨10.1051/medsci/2022102⟩
The biological clock is a set of evolutionarily conserved "clock proteins" that generate circadian rhythms in behavior and physiological processes. The clock programs these processes at specific times of the day, allowing the organism to optimize its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::79f080c5727fdad587c229360ca2c6af
https://hal.science/hal-03778841/document
https://hal.science/hal-03778841/document