Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Benoit Miotto"'
Autor:
David Rombaut, Carine Lefèvre, Tony Rached, Sabrina Bondu, Anne Letessier, Raphael M. Mangione, Batoul Farhat, Auriane Lesieur-Pasquier, Daisy Castillo-Guzman, Ismael Boussaid, Chloé Friedrich, Aurore Tourville, Magali De Carvalho, Françoise Levavasseur, Marjorie Leduc, Morgane Le Gall, Sarah Battault, Marie Temple, Alexandre Houy, Didier Bouscary, Lise Willems, Sophie Park, Sophie Raynaud, Thomas Cluzeau, Emmanuelle Clappier, Pierre Fenaux, Lionel Adès, Raphael Margueron, Michel Wassef, Samar Alsafadi, Nicolas Chapuis, Olivier Kosmider, Eric Solary, Angelos Constantinou, Marc-Henri Stern, Nathalie Droin, Benoit Palancade, Benoit Miotto, Frédéric Chédin, Michaela Fontenay
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Myelodysplastic syndromes (MDS) with mutated SF3B1 gene present features including a favourable outcome distinct from MDS with mutations in other splicing factor genes SRSF2 or U2AF1. Molecular bases of these divergences are poorly understoo
Externí odkaz:
https://doaj.org/article/123566d884df484c9b7e6a5d549470f7
Autor:
Alya Boutabba, Fadoua Missaoui, Akram Dlala, Hela Kamoun, Khalil Ben Salem, Amira Gabsi, Hadhemi Rejeb, Anne Letessier, Benoit Miotto, Raja Marrakchi
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Lung cancer is one of the most common type of cancer and, despite significant advances in screening and diagnosis approaches, a large proportion of patients at diagnosis still present advanced stages of the disease with distant metastasis an
Externí odkaz:
https://doaj.org/article/a58332740873482d8cd0e99e3d4d923f
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2122-2143 (2022)
DNA methylation on CpGs regulates transcription in mammals, both by decreasing the binding of methylation-repelled factors and by increasing the binding of methylation-attracted factors. Among the latter, zinc finger proteins have the potential to bi
Externí odkaz:
https://doaj.org/article/50bf0baa68ce4980ae358c184e0267f6
Autor:
Maud De Dieuleveult, Martin Bizet, Laurence Colin, Emilie Calonne, Martin Bachman, Chao Li, Irina Stancheva, Benoit Miotto, François Fuks, Rachel Deplus
Publikováno v:
Epigenetics, Vol 17, Iss 4, Pp 422-443 (2022)
Ten-Eleven Translocation (TET) proteins convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) leading to a dynamic epigenetic state of DNA that can influence transcription and chromatin organization. While TET proteins interact with comple
Externí odkaz:
https://doaj.org/article/5adf755568894664aea40507c9488355
Autor:
Philippe Fernandes, Benoit Miotto, Claude Saint-Ruf, Maha Said, Viviana Barra, Viola Nähse, Silvia Ravera, Enrico Cappelli, Valeria Naim
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Fernandes et al. discover a connection between the mitochondrial stress response and genomic stability. They find that transcription of common fragile site (CFS) genes is induced by mitochondrial stress, whereas a regulator of CFS stability, FANCD2,
Externí odkaz:
https://doaj.org/article/e0f19b4840814983bdab55f7127e98cd
Autor:
Benoit Miotto, Moredreck Chibi, Ping Xie, Stéphane Koundrioukoff, Hanlie Moolman-Smook, David Pugh, Michelle Debatisse, Fuchu He, Lingqiang Zhang, Pierre-Antoine Defossez
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 575-587 (2014)
Summary: Faithful DNA replication is essential for the maintenance of genome integrity. Incomplete genome replication leads to DNA breaks and chromosomal rearrangements, which are causal factors in cancer and other human diseases. Despite their impor
Externí odkaz:
https://doaj.org/article/f4d98e21d46c47f69fdb4ef660128230
Autor:
Matthieu Hainaut, Thierry Sagnier, Hélène Berenger, Jacques Pradel, Yacine Graba, Benoit Miotto
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32882 (2012)
The adult thorax of Drosophila melanogaster is covered by a stereotyped pattern of mechanosensory bristles called macrochaetes. Here, we report that the MYST containing protein Chameau (Chm) contributes to the establishment of this pattern in the mos
Externí odkaz:
https://doaj.org/article/11f8eee7a1a440c1a3139660447a42d1
Autor:
Rana Lebdy, Marine Canut, Julie Patouillard, Jean-Charles CADORET, Anne Letessier, Josiane Ammar, Jihane Basbous, Serge Urbach, Benoit Miotto, Angelos Constantinou, Raghida Abou-Merhi, Cyril Ribeyre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::930ffa978e7bb3347fd1b8eabbf6887a
https://doi.org/10.15252/rc.2023884586
https://doi.org/10.15252/rc.2023884586
Autor:
Rana Lebdy, Marine Canut, Julie Patouillard, Jean-Charles Cadoret, Anne Letessier, Josiane Ammar, Jihane Basbous, Serge Urbach, Benoit Miotto, Angelos Constantinou, Raghida Abou Merhi, Cyril Ribeyre
SummaryDNA replication requires specific proteins that protect replication forks and so prevent the formation of DNA lesions that may damage the genome. Identification of new proteins involved in these processes is essential to understand how cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97d558793f10dc50551ee69c1d75691b
https://doi.org/10.1101/2022.10.27.514025
https://doi.org/10.1101/2022.10.27.514025
Autor:
David Rombaut, Carine Lefevre, Batoul Farhat, Sabrina Bondu, Anne Letessier, Auriane Lesieur-Pasquier, Daisy Castillo-Guzman, Marjorie Leduc, Emilie-Fleur Gautier, Virginie Chesnais, Alice Rousseau, Ismael Boussaid, Sarah Battault, Alexandre Houy, Didier Bouscary, Lise Willems, Nicolas Chapuis, Sophie Park, Sophie Raynaud, Thomas Cluzeau, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Eric Solary, Raphael Margueron, Michel Wassef, Olivier Kosmider, Samar Alsafadi, Nathalie Droin, Angelos Constantinou, Marc-Henri Stern, Benoit Miotto, Frederic Chedin, Michaela Fontenay
Publikováno v:
Blood. 140:215-216