Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Benoit Lechat"'
Autor:
Tonci Ivanisevic, Mikhail Steklov, Benoit Lechat, Christopher Cawthorne, Willy Gsell, Greetje Vande Velde, Christophe Deroose, Koen Van Laere, Uwe Himmelreich, Raj N Sewduth, Anna A Sablina
Publikováno v:
Cancer Communications, Vol 43, Iss 12, Pp 1386-1390 (2023)
Externí odkaz:
https://doaj.org/article/afbe80ee102246ea8bc990602c51107f
Autor:
Raj N. Sewduth, Paolo Carai, Tonci Ivanisevic, Mingzhen Zhang, Hyunbum Jang, Benoit Lechat, Delphi Van Haver, Francis Impens, Ruth Nussinov, Elizabeth Jones, Anna Sablina
Publikováno v:
Advanced Science, Vol 10, Iss 36, Pp n/a-n/a (2023)
Abstract Blood flow produces shear stress exerted on the endothelial layer of the vessels. Spatial characterization of the endothelial proteome is required to uncover the mechanisms of endothelial activation by shear stress, as blood flow varies in t
Externí odkaz:
https://doaj.org/article/d7f20403a7564fbf98790f9140c65dc3
Autor:
Rudra Kashyap, Marielle Balzano, Benoit Lechat, Kathleen Lambaerts, Antonio Luis Egea-Jimenez, Frédérique Lembo, Joanna Fares, Sofie Meeussen, Sebastian Kügler, Anton Roebroek, Guido David, Pascale Zimmermann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Exosomal transfers represent an important mode of intercellular communication. Syntenin is a small scaffold protein that, when binding ALIX, can direct endocytosed syndecans and syndecan cargo to budding endosomal membranes, supporting the f
Externí odkaz:
https://doaj.org/article/5818175db7fd4b9fba6c41d314e2d576
Autor:
Jan R. Detrez, Hervé Maurin, Kristof Van Kolen, Roland Willems, Julien Colombelli, Benoit Lechat, Bart Roucourt, Fred Van Leuven, Sarah Baatout, Peter Larsen, Rony Nuydens, Jean-Pierre Timmermans, Winnok H. De Vos
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 398-409 (2019)
We have exploited whole brain microscopy to map the progressive deposition of hyperphosphorylated tau in intact, cleared mouse brain. We found that the three-dimensional spreading pattern of hyperphosphorylated tau in the brain of an aging Tau.P301L
Externí odkaz:
https://doaj.org/article/119ac8d690064ea99cc5b5a136436f56
Autor:
Malgorzata Urbanska, Paulina Kazmierska-Grebowska, Tomasz Kowalczyk, Bartosz Caban, Karolina Nader, Barbara Pijet, Katarzyna Kalita, Agata Gozdz, Herman Devijver, Benoit Lechat, Tomasz Jaworski, Wieslawa Grajkowska, Krzysztof Sadowski, Sergiusz Jozwiak, Katarzyna Kotulska, Jan Konopacki, Fred Van Leuven, Erwin A. van Vliet, Eleonora Aronica, Jacek Jaworski
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 377-387 (2019)
Background: Glycogen synthase kinase-3β (GSK3β) is a key regulator of cellular homeostasis. In neurons, GSK3β contributes to the control of neuronal transmission and plasticity, but its role in epilepsy remains to be defined. Methods: Biochemical
Externí odkaz:
https://doaj.org/article/ccb24ce7f72a4cd2a2d94b67aaf14db7
Autor:
Natalia Crespo-Biel, Clara Theunis, Peter Borghgraef, Benoit Lechat, Herman Devijver, Hervé Maurin, Fred Van Leuven
Publikováno v:
Neurobiology of Disease, Vol 67, Iss , Pp 119-132 (2014)
Tau.P301L transgenic mice suffer precocious mortality between ages 8 and 11 months, resulting from upper airway defects caused by tauopathy in autonomic brainstem circuits that control breathing (Dutschmann et al., 2010). In individual mice, the clin
Externí odkaz:
https://doaj.org/article/2e7701d84aea4ee39f0cda292ac223f9
Autor:
Hervé Maurin, Seon-Ah Chong, Igor Kraev, Heather Davies, Anna Kremer, Claire Marie Seymour, Benoit Lechat, Tomasz Jaworski, Peter Borghgraef, Herman Devijver, Geert Callewaert, Michael G Stewart, Fred Van Leuven
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87605 (2014)
The stratum lacunosum moleculare (SLM) is the connection hub between entorhinal cortex and hippocampus, two brain regions that are most vulnerable in Alzheimer's disease. We recently identified a specific synaptic deficit of Nectin-3 in transgenic mo
Externí odkaz:
https://doaj.org/article/81e57e7a453c43b2be77bb66b288a51e
Autor:
Hervé Maurin, Claire Marie Seymour, Benoit Lechat, Peter Borghgraef, Herman Devijver, Tomasz Jaworski, Mathias V Schmidt, Sebastian Kuegler, Fred Van Leuven
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63589 (2013)
Cell adhesion molecules are important structural substrates, required for synaptic plasticity and synaptogenesis. CAMs differ widely in their expression throughout different brain regions and their specific structural and functional roles in the brai
Externí odkaz:
https://doaj.org/article/cd5f0634206b4d8fb8977d3ab0584a54
Autor:
Tomasz Jaworski, Ilse Dewachter, Benoit Lechat, Sophie Croes, Annelies Termont, David Demedts, Peter Borghgraef, Herman Devijver, Robert K Filipkowski, Leszek Kaczmarek, Sebastian Kügler, Fred Van Leuven
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7280 (2009)
In Alzheimer's disease tauopathy is considered secondary to amyloid, and the duality obscures their relation and the definition of their respective contributions.Transgenic mouse models do not resolve this problem conclusively, i.e. the relative hier
Externí odkaz:
https://doaj.org/article/94442942af4447aba6d87225d21ee6ef
Autor:
Anna A. Sablina, Francis Impens, Sven Eyckerman, Nikky Corthout, Delphi Van Haver, Teresa Mendes Maia, Benoit Lechat, Nathan Criem, Silvia Pandolfi, Maria Francesca Baietti, Raj Nayan Sewduth, Mikhail Steklov, Peihua Zhao, Paul Najm
Supplementary Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf102c8e5550dda271e4b4d424d11e59
https://doi.org/10.1158/0008-5472.22429188.v1
https://doi.org/10.1158/0008-5472.22429188.v1