Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Benoit D. Roussel"'
Autor:
Melissa Jauquet, Pierre Gagnepain, Estelle La Porte, Audrey M. Thiebaut, Ambre Rochey, Helene Legros, Baptiste Laine, Marion Berthelot, Valerie Roussel, Joan Montaner, Barbara Casolla, Denis Vivien, Eloise Lemarchand, Richard Macrez, Benoit D. Roussel
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 11, Pp 2877-2890 (2024)
Abstract Objective Stroke is the leading cause of death and disability. Timely differentiation between ischemic stroke, hemorrhagic stroke, and stroke mimics is critical for tailored treatment and triage. To accelerate the identification of stroke's
Externí odkaz:
https://doaj.org/article/81675af09f4843a0be02ff1cf4e75c88
Autor:
Elodie Hedou, Sara Douceau, Arnaud Chevilley, Alexandre Varangot, Audrey M. Thiebaut, Hortense Triniac, Isabelle Bardou, Carine Ali, Mike Maillasson, Tiziana Crepaldi, Paolo Comoglio, Eloïse Lemarchand, Véronique Agin, Benoit D. Roussel, Denis Vivien
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13483 (2021)
Tissue-type plasminogen activator (tPA) plays roles in the development and the plasticity of the nervous system. Here, we demonstrate in neurons, that by opposition to the single chain form (sc-tPA), the two-chains form of tPA (tc-tPA) activates the
Externí odkaz:
https://doaj.org/article/32c987712ef14d83893d9b7cb5bf075c
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Cerebral ischemia is a complex pathology involving a cascade of cellular mechanisms, which deregulate proteostasis and lead to neuronal death. Proteostasis refers to the equilibrium between protein synthesis, folding, transport, and protein degradati
Externí odkaz:
https://doaj.org/article/2a44b3793ef3487eb15a3853ef82b5db
Autor:
Cyrille Orset, Carine Ali, Valérie Carraro, Jérôme Parcq, Benoit D. Roussel, Isabelle Bardou, Audrey M Thiebaut, Anne Terrisse, Denis Vivien, Jérôme Leprince, Eloise Lemarchand, Morgane Louessard, Alain Bruhat, Pierre Fafournoux
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, 2017, 24 (9), pp.1518-1529. ⟨10.1038/cdd.2017.35⟩
Cell Death and Differentiation, Nature Publishing Group, 2017, 24 (9), pp.1518-1529. ⟨10.1038/cdd.2017.35⟩
Cell Death and Differentiation, 2017, 24 (9), pp.1518-1529. ⟨10.1038/cdd.2017.35⟩
Cell Death and Differentiation, Nature Publishing Group, 2017, 24 (9), pp.1518-1529. ⟨10.1038/cdd.2017.35⟩
This project was supported by the Region Basse-Normandie and the AXA postdoctoral fellowship program, the INSERM, and the university of Caen. We thank Mr Gilbert Pigree and Mr Maxime Lemarchand for their help with the production of radioactive tPA (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41b5a9ee025acbac789d4acfd9c09f4
https://doi.org/10.1038/cdd.2017.35
https://doi.org/10.1038/cdd.2017.35
Autor:
Maxime Gauberti, Manuel Yepes, Audrey M Thiebaut, Benoit D. Roussel, Denis Vivien, Sara Martinez de Lizarrondo, Carine Ali
Publikováno v:
The Lancet. Neurology. 17(12)
Summary Although recent technical advances in thrombectomy have revolutionised acute stroke treatment, prevalence of disability and death related to stroke remain high. Therefore, plasminogen activators—eukaryotic, bacterial, or engineered forms th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e644908b1ee1eca51d1eb6623e5d17da
https://pubmed.ncbi.nlm.nih.gov/30507392
https://pubmed.ncbi.nlm.nih.gov/30507392
Publikováno v:
Springer Series in Translational Stroke Research ISBN: 9783319453446
Worldwide, ischaemic stroke is a major cause of death and the leading cause of acquired disability. To date, pharmacological thrombolysis with tissue-type plasminogen activator (alone or with mechanical thrombectomy) remains the gold standard acute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0112ab625f5b8d2019214953a7520c
https://doi.org/10.1007/978-3-319-45345-3_13
https://doi.org/10.1007/978-3-319-45345-3_13
Publikováno v:
Epileptic disorders : international epilepsy journal with videotape. 18(S2)
Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a conformational proteinopathy characterised by neuronal inclusion bodies composed of the serine protease inhibitor (SERPIN), neuroserpin. Presenting clinically as a familial dement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8b36dc87cd9c6ff37b55ab7eb25ec4
https://pubmed.ncbi.nlm.nih.gov/27618835
https://pubmed.ncbi.nlm.nih.gov/27618835
Autor:
Marie Hébert, Aurélien Quenault, Denis Vivien, Pauline Obiang, Antoine Anfray, Cyrille Orset, Arnaud Chevilley, Morgane Louessard, Eric Maubert, Etienne Save, Véronique Agin, Benoit D. Roussel, Sara Martinez de Lizarrondo
Publikováno v:
Cerebral Cortex
Cerebral Cortex, 2016, ⟨10.1093/cercor/bhw275⟩
Cerebral Cortex, Oxford University Press (OUP), 2016, ⟨10.1093/cercor/bhw275⟩
Europe PubMed Central
Cerebral Cortex, 2016, ⟨10.1093/cercor/bhw275⟩
Cerebral Cortex, Oxford University Press (OUP), 2016, ⟨10.1093/cercor/bhw275⟩
Europe PubMed Central
International audience; In humans, spatial cognition and navigation impairments are a frequent situation during physiological and pathological aging, leading to a dramatic deterioration in the quality of life. Despite the discovery of neurons with lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb40b305a698bef09fa7d8240ff1d37c
https://doi.org/10.1093/cercor/bhw275
https://doi.org/10.1093/cercor/bhw275
Publikováno v:
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2016, 53 (3), pp.1540-1550. 〈10.1007/s12035-015-9114-5〉
Molecular Neurobiology, Humana Press, 2016, 53 (3), pp.1540-1550. ⟨10.1007/s12035-015-9114-5⟩
Molecular Neurobiology, Humana Press, 2016, 53 (3), pp.1540-1550. 〈10.1007/s12035-015-9114-5〉
Molecular Neurobiology, Humana Press, 2016, 53 (3), pp.1540-1550. ⟨10.1007/s12035-015-9114-5⟩
International audience; Reverse transcription quantitative-polymerase chain reaction (RT-qPCR) has become a routine method in many laboratories. Normalization of data from experimental conditions is critical for data processing and is usually achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcc5870fcf0f51ec64a52402bad2114
http://www.hal.inserm.fr/inserm-01296960
http://www.hal.inserm.fr/inserm-01296960
Autor:
Lakshmi Segu, John Kirkpatrick, Konstantinos Thalassinos, Mun Peak Nyon, Benoit D. Roussel, Noor Kalsheker, Anathe O.M. Patschull, Christopher A. Waudby, Tracey E. Barrett, Geraldine Levy, David A. Lomas, John Christodoulou, Bibek Gooptu, Richard A. Kerr, Lisa D. Cabrita, Ugo I. Ekeowa, Marian Hill
Publikováno v:
Structure(London, England:1993)
Summary In conformational diseases, native protein conformers convert to pathological intermediates that polymerize. Structural characterization of these key intermediates is challenging. They are unstable and minimally populated in dynamic equilibri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d646ad85ac7a0db0dcb3e804cc64da