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pro vyhledávání: '"Benoit Culot"'
Autor:
Benoit Culot, Armel Stockis, E. Bourgogne, Sylvie Dell'Aiera, Jean-Marie Nicolas, Hugues Chanteux
Publikováno v:
Journal of Chromatography B. 1086:138-145
Brivaracetam (BRV) is a new high affinity synaptic vesicle protein 2A ligand recently approved for adults with partial-onset seizures. As a support to in vitro metabolism assays, a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method coup
Autor:
Marc Lastelle, Walthère Dewé, Dominique Ingels, Xavier Taillieu, Benoit Culot, Nathalie Evrard, Gaëlle Saucez, Michaël De Smet
Publikováno v:
Journal of Chromatography B. 854:183-191
The lead optimization phase of drug discovery requires high-throughput analyses for quantification in biological matrices and in plasma in particular. Over the last decade, some technical innovations allowed the pharmaceutical industry to improve the