Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Benoit Cardinal-David"'
Autor:
Benoit Cardinal-David, David Hanna, Jeffrey T. Bien, Anuj A. Verma, Zhe Wang, Christopher Vitale, Kaid C. Harper, Moiz Diwan, Daniel D. Caspi
Publikováno v:
Organic Process Research & Development. 25:2473-2481
Autor:
Rajarathnam E. Reddy, Soma Ghosh, Eric A. Voight, John R. Bellettini, Selvakumar Balaraman, Abhishek Ashok, Jianguo Ji, Brian J. Kotecki, David R. Hill, Timothy B. Towne, James P. Stambuli, Benoit Cardinal-David, Minshan Shou, Mark A. Matulenko, Alexander D Huters, Vincent S. Chan, Russell C. Klix, Justin A. Simanis
Publikováno v:
The Journal of Organic Chemistry. 87:1986-1995
Foslevodopa (FLD, levodopa 4'-monophosphate, 3) and foscarbidopa (FCD, carbidopa 4'-monophosphate, 4) were identified as water-soluble prodrugs of levodopa (LD, 1) and carbidopa (CD, 2), respectively, which are useful for the treatment of Parkinson's
Publikováno v:
Canadian Journal of Chemistry. 98:466-470
An acyclic approach to synthesize thiofuranoside N-glycosides bearing an adenine nucleobase is presented herein. This approach provides a significant improvement in terms of regio- and diastereoselectivity compared with the current paradigms used for
Publikováno v:
Angewandte Chemie International Edition. 50:1678-1682
The stereoselective construction of highly functionalized small- and medium-sized carbocycles from simple substrates is an ongoing objective in organic synthesis. One approach to this goal is the use of small organic molecules that have been designed
Publikováno v:
Nature chemistry
Enzymes are a continuing source of inspiration for the design of new chemical reactions that proceed with efficiency, high selectivity and minimal waste. In many biochemical processes, different catalytic species, such as Lewis acids and bases, are i
Publikováno v:
Organic Letters. 11:3148-3151
A novel strategy for the stereoselective construction of all-carbon quaternary centers on acyclic molecules using a two-step tandem process is reported. The first step involves an intramolecular and stereoselective atom transfer radical cyclization r
Publikováno v:
Current Organic Chemistry. 10:1939-1961
Publikováno v:
Tetrahedron Letters. 43:7067-7071
Reported herein is the iteration of a strategy employing a Mukaiyama reaction in tandem with a hydrogen transfer reaction for the elaboration of four polypropionate motifs containing the anti – anti unit. In this process, Lewis acid acts as the key
Publikováno v:
Coordination Chemistry Reviews. :509-543
The electronic spectra of trans-MCl2(X2O)4n+ complexes (M: Ni2+, Co2+, V3+, Cr3+ and X: H, D) are analyzed in order to understand interactions between electronic states. We present detailed low-temperature polarized absorption spectra of single cryst
Publikováno v:
Journal of the American Chemical Society. 132:5345-5347
A new approach that takes advantage of N-heterocyclic carbene/Lewis acid cooperative catalysis provides access to cis-1,3,4-trisubstituted cyclopentenes from enals and chalcone derivatives with high levels of diastereoselectivity and enantioselectivi