Výsledky vyhledávání - "Benoit Blomme"

Mechanical strain induces a pro-fibrotic phenotype in human mitral valvular interstitial cells through RhoC/ROCK/MRTF-A and Erk1/2 signaling pathways

Autor: Charles Lambert, Jean-Olivier Defraigne, Alain Colige, Maurice Radermecker, Betty Nusgens, Alexia Hulin, Benoit Blomme, Christophe Deroanne

Publikováno v: Journal of Molecular and Cellular Cardiology. 135:149-159

The mitral valve is a complex multilayered structure populated by fibroblast-like cells, valvular interstitial cells (VIC) which are embedded in an extracellular matrix (ECM) scaffold and are submitted to the mechanical deformations affecting valve a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b16066e72910ab70d617e67ede7106
https://doi.org/10.1016/j.yjmcc.2019.08.008

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Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer

Autor: Oriane Carnet, Vincent Bours, Joseph Martial, Benoit Blomme, Sébastien Tabruyn, Marc Thiry, Claire Josse, Pierre Frères, Agnès Noël, Olivier Nivelles, Stella Dederen, Michelle Lion, Ingrid Struman, Guy Jerusalem, Nicolas Bovy

Publikováno v: Oncotarget
Scopus-Elsevier

The interaction between tumor cells and their microenvironment is an essential aspect of tumor development. Therefore, understanding how this microenvironment communicates with tumor cells is crucial for the development of new anti-cancer therapies.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ea37b316a17cc2ef064e076cbdc140
https://pubmed.ncbi.nlm.nih.gov/25860935

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