Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Benoit, Witkowski"'
Autor:
Anaïs Pepey, Marc Souris, Saorin Kim, Thomas Obadia, Sophy Chy, Malen Ea, Sivkeng Ouk, Franck Remoue, Siv Sovannaroth, Ivo Mueller, Benoit Witkowski, Amélie Vantaux
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background The Great Mekong Subregion has attained a major decline in malaria cases and fatalities over the last years, but residual transmission hotspots remain, supposedly fueled by forest workers and migrant populations. This study aimed
Externí odkaz:
https://doaj.org/article/480efc3fce4f4777af47e15943490d50
Autor:
Sophea Iv, Chea Nguon, Phanith Kong, Téphanie Sieng, Sreynet Srun, Céline Christiansen-Jucht, Chanvong Kul, Thornleaksmey Lorn, Sophy Chy, Jean Popovici, Amélie Vantaux, Benoit Witkowski, Antoine Berry, Patrice Piola, Claude Flamand
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 47, Iss , Pp 101093- (2024)
Summary: Background: Cambodia targets P. falciparum malaria elimination by 2023 and all human malaria species by 2025, aligning with WHO's Mekong Malaria Elimination program. The Intermittent Preventive Treatment for Forest Goers (IPTf) project aimed
Externí odkaz:
https://doaj.org/article/86d75247ba8844dea53ae6eb31aa10cb
Autor:
Mirco Sandfort, Wuelton Monteiro, Marcus Lacerda, Wang Nguitragool, Jetsumon Sattabongkot, Andreea Waltmann, Henrik Salje, Amélie Vantaux, Benoit Witkowski, Leanne J. Robinson, Ivo Mueller, Michael White
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Over the last decades, enormous successes have been achieved in reducing malaria burden globally. In Latin America, South East Asia, and the Western Pacific, many countries now pursue the goal of malaria elimination by 2030. It is
Externí odkaz:
https://doaj.org/article/37ed62f059d546afb978f4df0af9ed4f
Autor:
Emily Lynch, Tomas O. Jensen, Bachir Assao, Menard Chihana, Thadeous Turuho, Dan Nyehangane, John B. Manyok, Harriet Pasquale, Nimol Khim, Benoit Witkowski, Matthew E. Coldiron
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-8 (2022)
Abstract Background Rapid diagnostic tests (RDT) for malaria are the primary tool for malaria diagnosis in sub-Saharan Africa but the utility of the most commonly used histidine-rich protein 2 (HRP2) antigen-based tests is limited in high transmissio
Externí odkaz:
https://doaj.org/article/dabd822dda704dc694e4da31f873f9c3
Autor:
Laura E. de Vries, Patrick A. M. Jansen, Catalina Barcelo, Justin Munro, Julie M. J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta-Gatsi, Rob W. M. Henderson, Tonnie Huijs, Karin M. J. Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna C. C. Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V. C. Guido, María Belén Jiménez-Diaz, Dhelio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here, de Vries et al. perform a pre-clinical characterization of the antimalarial compound MMV693183: the compound targets acetyl-CoA synthetase, has efficacy in humanized mice against Plasmodium falciparum infection, blocks transmission to mosquito
Externí odkaz:
https://doaj.org/article/5a569da9aa694e86aa5e04aa0c21ba75
Autor:
Flore Nardella, Irina Dobrescu, Haitham Hassan, Fabien Rodrigues, Sabine Thiberge, Liliana Mancio-Silva, Ambre Tafit, Corinne Jallet, Véronique Cadet-Daniel, Stéphane Goussin, Audrey Lorthiois, Yoann Menon, Nicolas Molinier, Dany Pechalrieu, Christophe Long, François Sautel, Mariette Matondo, Magalie Duchateau, Guillaume Médard, Benoit Witkowski, Artur Scherf, Ludovic Halby, Paola B. Arimondo
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105940- (2023)
Summary: Malaria eradication requires the development of new drugs to combat drug-resistant parasites. We identified bisbenzylisoquinoline alkaloids isolated from Cocculus hirsutus that are active against Plasmodium falciparum blood stages. Synthesis
Externí odkaz:
https://doaj.org/article/f12af47207ad40a38e61010f2bc8e9c9
Autor:
Surafel K. Tebeje, Wakweya Chali, Elifaged Hailemeskel, Jordache Ramjith, Abrham Gashaw, Temesgen Ashine, Desalegn Nebret, Endashaw Esayas, Tadele Emiru, Tizita Tsegaye, Karina Teelen, Kjerstin Lanke, Eizo Takashima, Takafumi Tsuboi, Nichole D. Salinas, Niraj H. Tolia, David Narum, Chris Drakeley, Benoit Witkowski, Amelie Vantaux, Matthijs M. Jore, William J. R. Stone, Ivo S. Hansen, Fitsum G. Tadesse, Teun Bousema
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
Naturally acquired antibodies may reduce the transmission of Plasmodium gametocytes to mosquitoes. Here, we investigated associations between antibody prevalence and P. vivax infectivity to mosquitoes. A total of 368 microscopy confirmed P. vivax sym
Externí odkaz:
https://doaj.org/article/58a23394fab249ddb737615088050c79
Autor:
Amélie Vantaux, Julie Péneau, Caitlin A. Cooper, Dennis E. Kyle, Benoit Witkowski, Steven P. Maher
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Plasmodium vivax, one species of parasite causing human malaria, forms a dormant liver stage, termed the hypnozoite, which activate weeks, months or years after the primary infection, causing relapse episodes. Relapses significantly contribute to the
Externí odkaz:
https://doaj.org/article/b308d2614d024f41b268c7ed1f62fb52
Autor:
Anthony A. Ruberto, Steven P. Maher, Amélie Vantaux, Chester J. Joyner, Caitlin Bourke, Balu Balan, Aaron Jex, Ivo Mueller, Benoit Witkowski, Dennis E. Kyle
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The resilience of Plasmodium vivax, the most widely-distributed malaria-causing parasite in humans, is attributed to its ability to produce dormant liver forms known as hypnozoites, which can activate weeks, months, or even years after an initial mos
Externí odkaz:
https://doaj.org/article/d4574b7d96d4492ebe513519b0913d9a
Autor:
Anthony A Ruberto, Caitlin Bourke, Amélie Vantaux, Steven P Maher, Aaron Jex, Benoit Witkowski, Georges Snounou, Ivo Mueller
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 8, p e0010633 (2022)
BackgroundPlasmodium vivax sporozoites reside in the salivary glands of a mosquito before infecting a human host and causing malaria. Previous transcriptome-wide studies in populations of these parasite forms were limited in their ability to elucidat
Externí odkaz:
https://doaj.org/article/e86c83b8dd0d45d781a5cf73f6cb53a2