Výsledky vyhledávání - "Benoit, Sion"

Akademický článek

Blocking α2δ-1 Subunit Reduces Bladder Hypersensitivity and Inflammation in a Cystitis Mouse Model by Decreasing NF-kB Pathway Activation

Autor: Ludivine Boudieu, Sarah Mountadem, Amandine Lashermes, Mathieu Meleine, Lauriane Ulmann, François Rassendren, Youssef Aissouni, Benoit Sion, Frédéric Antonio Carvalho, Denis Ardid

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

Bladder pain is frequently associated with bladder inflammation, as in conditions like interstitial cystitis (IC), for which current analgesic therapies have limited efficacy. The antinociceptive effect of alpha-2-delta (α2δ) ligands on inflammatio

Externí odkaz: https://doaj.org/article/02b325e94e6d4fbf8d5c9393c91bc4b7

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Can chronopharmacology improve the therapeutic management of neurological diseases?

Autor: Benoit Sion, Mélina Bégou

Publikováno v: Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, Wiley, 2021, 35 (3), pp.564-581. ⟨10.1111/fcp.12659⟩

International audience; The importance of circadian rhythm dysfunctions in the pathophysiology of neurological diseases has been highlighted recently. Chronopharmacology principles imply that tailoring the timing of treatments to the circadian rhythm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c363162998ce79995d1d32c4a172699
https://hal.uca.fr/hal-03554969

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Physiologie de l’œil et principes généraux de la vision

Autor: Benoit Sion, Christine Courteix

Publikováno v: Actualités Pharmaceutiques. 57:20-24

Resume La vision est la sensibilite sensorielle dediee a la perception et a l’integration d’informations visuelles. Les etapes de ce mecanisme comprennent la refraction de la lumiere, qui depend des proprietes biophysiques de l’œil, la phototr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4baf9b90eb710adba076b9d1a697b7e3
https://doi.org/10.1016/j.actpha.2018.03.004

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l-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration

Autor: A.-M. Privat, Benoit Sion, Marie-Paule Vasson, N. Davin, Christine Courteix, Alain Eschalier, Lusliany J. Rondon, Marie-Chantal Farges

Publikováno v: European Journal of Nutrition
European Journal of Nutrition, Springer Verlag, 2017, 11 p. ⟨10.1007/s00394-017-1508-x⟩
European Journal of Nutrition, Springer Verlag, 2017, 57 (7), 11 p. ⟨10.1007/s00394-017-1508-x⟩

Neuropathic pain is a common diabetic complication. It is characterized by symptoms of spontaneous and stimulus-evoked pain including hyperalgesia and allodynia. L-Arginine is a common precursor of many metabolites of biological interest, in particul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284e3aa83360ccfa1a2d525ce5e79ff1
https://doi.org/10.1007/s00394-017-1508-x

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Stimulus Artifact Removal Using Matrix Pencil Method

Autor: Christophe Pasquier, Benoit Sion, Lénaïc Monconduit, Khalil El Khamlichi Drissi, Francois Gabrielli, Zied Mizouri

Publikováno v: SoftCOM

The paper deals with a novel technique to identify the artifact shape and reduce residual threat during its removal. The method is based on the stimulus artifact reconstruction by using the high resolution Matrix Pencil method. The proposed technique

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe97b6a009e8650965714b6bb1e30a84
https://doi.org/10.23919/softcom.2018.8555803

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5-HT2A Receptors and Pain

Autor: Pierre-Yves Martin, Amandine Dupuis, Benoit Sion, Christine Courteix

Publikováno v: 5-HT2A Receptors in the Central Nervous System ISBN: 9783319704722

Serotonin (5-hydroxytryptamine, 5-HT) is a key modulator of spinal nociceptive transmission. Among 5-HT receptors, the 5-HT2A subtype plays a critical role in the modulation of nociceptive information. Both pro- and antinociceptive effects of 5-HT2A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a1f814392285cd2ab01e8e2e98a52a6
https://doi.org/10.1007/978-3-319-70474-6_14

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Adherent-Invasive E. coli enhances colonic hypersensitivity and P2X receptors expression during post-infectious period

Autor: Frederic A. Carvalho, Agathe Gelot, Nicolas Barnich, Amandine Lashermes, Ludivine Boudieu, Julie Barbier, Benoit Sion, Denis Ardid

Publikováno v: Gut microbes
Gut microbes, Taylor & Francis, 2017, 9 (1), pp.26-37. ⟨10.1080/19490976.2017.1361091⟩
Gut microbes, 2017, 9 (1), pp.26-37. ⟨10.1080/19490976.2017.1361091⟩

International audience; Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD) are related gastrointestinal disorders characterized by abdominal pain associated with colonic hypersensitivity (CHS). Studies in humans have reported an abno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9298def37614a2830592b09ce901cbf8
https://hal.archives-ouvertes.fr/hal-02064637

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Increasing spinal 5-HT 2A receptor responsiveness mediates anti-allodynic effect and potentiates fluoxetine efficacy in neuropathic rats. Evidence for GABA release

Autor: Alain Eschalier, Amandine Dupuis, Benoit Sion, Maryse Chalus, Christine Courteix, Anne-Sophie Wattiez, Frédéric Libert, Jérémy Pinguet, Youssef Aissouni, Philippe Marin, Denis Ardid, Damien Richard

Publikováno v: Pharmacological Research
Pharmacological Research, 2017, 118, pp.93-103. ⟨10.1016/j.phrs.2016.09.021⟩
Pharmacological Research, Elsevier, 2017, 118, pp.93-103. ⟨10.1016/j.phrs.2016.09.021⟩

Antidepressants are one of the first line treatments for neuropathic pain but their use is limited by the incidence and severity of side effects of tricyclics and the weak effectiveness of selective serotonin reuptake inhibitors (SSRIs). Serotonin ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a15eb55a712d4cd2f47fed80fc4a9be
https://uca.hal.science/hal-01668391

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Colonic transit time is a driven force of the gut microbiota composition and metabolism: In vitro evidence

Autor: Benoit Sion, William Tottey, David Feria-Gervasio, Jean-François Martin, Jean-Louis Sébédio, Nadia Gaci, Jean-François Jarrige, Monique Alric, Jean-François Brugère, Estelle Pujos, Brigitte Laillet

Publikováno v: Journal of Neurogastroenterology and Motility
Journal of Neurogastroenterology and Motility, Korean Society of Neurogastroenterology and Motility, 2017, 23 (1), pp.124-134. ⟨10.5056/jnm16042⟩
Journal of Neurogastroenterology and Motility, Korean Society of Neurogastroenterology and Motility, 2017, 23 (1), pp.124-134. 〈10.5056/jnm16042〉
Journal of Neurogastroenterology and Motility, 2017, 23 (1), pp.124-134. ⟨10.5056/jnm16042⟩
Journal of Neurogastroenterology and Motility 1 (23), 124-134. (2017)

Jean-François Brugère thanks bachelors’students for their help, more specifically Céline Vidal, Claire Ardaens,Adeline Régnier, and Amandine Maurin, and Sylvain Denis forhis valuable help concerning in vitro systems. In memory of GeorgeT MacFar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d14000e11ae680c216cc44f2cf15a70
https://hal.archives-ouvertes.fr/hal-01595498/document

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Increasing spinal 5-HT

Autor: Amandine, Dupuis, Anne-Sophie, Wattiez, Jérémy, Pinguet, Damien, Richard, Frédéric, Libert, Maryse, Chalus, Youssef, Aissouni, Benoit, Sion, Denis, Ardid, Philippe, Marin, Alain, Eschalier, Christine, Courteix

Publikováno v: Pharmacological research. 118

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a931334ed52ea44da437e2c33bbba96b
https://pubmed.ncbi.nlm.nih.gov/27663259

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