Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Benoit, Roch"'
Autor:
Ekaterina Pisareva, Benoit Roch, Cynthia Sanchez, Brice Pastor, Alexia Mirandola, Mona Diab-Assaf, Thibault Mazard, Corinne Prévostel, Zahra Al Amir Dache, Alain R. Thierry
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: The function, origin and structural features of circulating nuclear DNA (cir-nDNA) and mitochondrial DNA (cir-mtDNA) are poorly known, even though they have been investigated in numerous clinical studies, and are involved in a number of
Externí odkaz:
https://doaj.org/article/7a7264fd0fcb4ed499b44e8e0b97b3c7
Autor:
Brice Pastor, Thierry André, Julie Henriques, Isabelle Trouilloud, Christophe Tournigand, Marine Jary, Thibault Mazard, Christophe Louvet, Simon Azan, Audrey Bauer, Benoit Roch, Cynthia Sanchez, Dewi Vernerey, Alain R. Thierry, Antoine Adenis
Publikováno v:
Molecular Oncology, Vol 15, Iss 9, Pp 2401-2411 (2021)
Circulating cell‐free DNA (cfDNA) contains circulating tumor DNA (ctDNA), which can be obtained from serial liquid biopsies to enable tumor genome analysis throughout the course of treatment. We investigated cfDNA and mutant ctDNA as potential biom
Externí odkaz:
https://doaj.org/article/f02f440ca5a84aa39afc541bd361c7bf
Autor:
Thomas Barthlott, Adam E. Handel, Hong Ying Teh, Rushika C. Wirasinha, Katrin Hafen, Saulius Žuklys, Benoit Roch, Stuart H. Orkin, Jean-Pierre de Villartay, Stephen R. Daley, Georg A. Holländer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Development of the T cells requires functions from thymic epithelial cells, whose development and function are epigenetically regulated. Here the authors show that inactivation of the polycomb repressive complex 2 (PRC2) alters the H3K27me3 configura
Externí odkaz:
https://doaj.org/article/bea5fbe30e2340e383f4864410b7a2fd
Autor:
Benoit Roch, Vincent Abramowski, Olivier Etienne, Stefania Musilli, Pierre David, Jean-Baptiste Charbonnier, Isabelle Callebaut, François D Boussin, Jean-Pierre de Villartay
Publikováno v:
eLife, Vol 10 (2021)
We developed an Xrcc4M61R separation of function mouse line to overcome the embryonic lethality of Xrcc4-deficient mice. XRCC4M61R protein does not interact with Xlf, thus obliterating XRCC4-Xlf filament formation while preserving the ability to stab
Externí odkaz:
https://doaj.org/article/9f2b7f8042e7416dbee800b5e8f5606b
Publikováno v:
In Revue de micropaléontologie June 2019 63:37-43
Autor:
Stefania Cuzzubbo, Benoit Roch, Guillaume Darrasse-Jèze, Benoit Hosten, Manon Leclercq, Nicolas Vignal, Claire Banissi, Eric Tartour, Antoine F. Carpentier
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14975 (2022)
We previously reported that a novel peptide vaccine platform, based on synthetic melanin nanoaggregates, triggers strong cytotoxic immune responses and significantly suppresses tumor growth in mice. However, the mechanisms underlying such an efficacy
Externí odkaz:
https://doaj.org/article/443295b67253452293982255b351f5ad
Autor:
Cynthia Sanchez, Benoit Roch, Thibault Mazard, Philippe Blache, Zahra Al Amir Dache, Brice Pastor, Ekaterina Pisareva, Rita Tanos, Alain R. Thierry
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
To unequivocally address their unresolved intimate structures in blood, we scrutinized the size distribution of circulating cell-free DNA (cfDNA) using whole-genome sequencing (WGS) from both double- and single-strand DNA library preparations (DSP an
Externí odkaz:
https://doaj.org/article/3894a79fa1854876a1eb8680e6c7d7c2
Publikováno v:
In Cretaceous Research November 2017 79:199-213
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Xlf/Cernunnos is unique among the core factors of the non-homologous end joining (NHEJ) DNA double strand breaks (DSBs) repair pathway, in the sense that it is not essential for V(D)J recombination in vivo and in vitro. Unlike other NHEJ deficient mi
Externí odkaz:
https://doaj.org/article/69933967aaa446038fc4b5f7cd6f86d5
Autor:
Jérôme Solassol, Pierre Brousset, Etienne Coyaud, Sylvain Godreuil, Abdelali Bouidioua, Benoit Roch, Jean-Louis Pujol, Xavier Quantin, Isabelle Rouquette, Romain Senal, Julien Mazieres, Julie A. Vendrell
Purpose:The detection of preexisting EGFRT790M subclones and the assessment of their clinical significance in the pretreatment of patients with EGFRT790M non–small cell lung cancer (NSCLC) remain unclear.Experimental Design:A total of 179 tumor sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ae5bfb4ae0374672fb199f0fdd465e
https://doi.org/10.1158/1078-0432.c.6527717
https://doi.org/10.1158/1078-0432.c.6527717
