Výsledky vyhledávání - "Benoit, Loup"

BPA disrupts meiosis I in oogonia by acting on pathways including cell cycle regulation, meiosis initiation and spindle assembly

Autor: Benoit Loup, Elodie Poumerol, Luc Jouneau, Paul A. Fowler, Corinne Cotinot, Béatrice Mandon-Pépin

Publikováno v: Reproductive Toxicology
Reproductive Toxicology, 2022, 111, p. 166-177. ⟨10.1016/j.reprotox.2022.06.001⟩

International audience; The negative in utero effects of bisphenol A (BPA) on female reproduction are of concern since the ovarian reserve of primordial follicles is constituted during the fetal period. This time-window is difficult to access, partic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d899ba0e75e43fdeaa30a87d9ececa1
https://doi.org/10.1016/j.reprotox.2022.06.001

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From a non‐targeted metabolomics approach to a targeted biomarkers strategy to highlight testosterone abuse in equine. Illustration of a methodological transfer between platforms and laboratories

Autor: Chloé Cloteau, Gaud Dervilly, Zied Kaabia, Florian Bagilet, Vivian Delcourt, Benoit Loup, Yann Guitton, Anne‐Lise Royer, Fabrice Monteau, Patrice Garcia, Marie‐Agnès Popot, Bruno Le Bizec, Ludovic Bailly‐Chouriberry

Publikováno v: Drug Testing and Analysis. 14:864-878

In order to overcome the challenge associated with the screening of Anabolic-Androgenic Steroids abuses in animal competitions, a non-targeted liquid chromatography coupled to high resolution mass spectrometry based metabolomics approach was implemen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e1ad99f7137890d42723a8f7d50da4
https://doi.org/10.1002/dta.3221

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Development of a Standardized Microflow LC Gradient to Enable Sensitive and Long-Term Detection of Synthetic Anabolic-Androgenic Steroids for High-Throughput Doping Controls

Autor: Marie-Agnès Popot, Vivian Delcourt, Isabelle Pottier, Patrice Garcia, Agnès Barnabé, Nasrine Mansoibou, Nicolai Bache, Yohan Glavieux, Benoit Loup, Benjamin Chabot, François Andre, Isabelle Perot, Ludovic Bailly-Chouriberry

Publikováno v: Analytical Chemistry. 93:15590-15596

Synthetic androgenic anabolic steroids (AAS) are banned compounds and considered as major threats by both racing and sports international authorities. Hence, doping control laboratories are continually looking into analytical improvements to increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317c46182add50c9d945dd44df308fb9
https://doi.org/10.1021/acs.analchem.1c03392

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LC‐HRMS/MS study of the prodrug ciclesonide and its active metabolite desisobutyryl‐ciclesonide in plasma after an inhalative administration to horses for doping control purposes

Autor: Zied Kaabia, Ludovic Bailly-Chouriberry, Marie-Agnès Popot, Sébastien Rouger, Vivian Delcourt, Patrice Garcia, Yves Moulard, Karine Dauriac, Benoit Loup, Stéphane Trevisiol, Ruediger Narbe, Sophie Boyer, Guillaume Groseille

Publikováno v: Drug Testing and Analysis. 14:252-261

Ciclesonide (CIC) is the first inhaled highly potent corticosteroid which does not cause any cortisol suppression. It has been developed for the treatment of asthma in human and more recently in equine. CIC is the active compound of Aservo® EquiHale

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59dd0d2423388cdd96530be357d6515
https://doi.org/10.1002/dta.3174

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TB500/TB1000 and SGF1000: A scientific approach for a better understanding of misbranded and adulterated drugs

Autor: Vivian Delcourt, Patrice Garcia, Benjamin Chabot, Agnès Barnabé, Maëlle Bouscarel, Benoit Loup, Marie‐Agnès Popot, Ludovic Bailly‐Chouriberry

Publikováno v: Drug testing and analysisREFERENCES.

Nowadays, numerous websites attempt to commercialize over the internet various products, regardless of the lack of approval by the EMA or the FDA either for human or veterinary use. These products are often produced after aborted drug development due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ef8f4146b12e2c5caa7b8b8691a469
https://pubmed.ncbi.nlm.nih.gov/36482504

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Validation of a metabolomics model to screen for a range of anabolic doping agents in horses

Autor: Chloé Cloteau, Gaud Dervilly, Benoit Loup, Zied Kaabia, Vivian Delcourt, Florian Bagilet, Guillaume Groseille, Karine Dauriac, Sabrina Fisher, Marie-Agnès Popot, Patrice Garcia, Bruno Le Bizec, Ludovic Bailly-Chouriberry

Despite their ban, Anabolic Androgenic Steroids (AAS) are considered as the most important threat for equine doping purposes. In the context of controlling such practices in horse racing, metabolomics has emerged as a promising alternative strategy t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84da97a4fc7e0cb69eca4bfaa3c47169
https://doi.org/10.21203/rs.3.rs-1824805/v1

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miRNAs detection in equine plasma by quantitative polymerase chain reaction for doping control: Assessment of blood sampling and study of eca‐miR‐144 as potential erythropoiesis stimulating agent biomarker

Autor: Marie-Agnès Popot, Agnès Barnabé, Marion Lhuaire, François Andre, Ludovic Bailly-Chouriberry, Patrice Garcia, Benoit Loup, Justine Avignon, Vivian Delcourt

Publikováno v: Drug Testing and Analysis. 14:953-962

Short half-life doping substances are, quickly eliminated and therefore difficult to control with traditional analytical chemistry methods. Indirect methods targeting biomarkers constitute an alternative to extend detection time frames in doping cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4be6418fd2f79d7ab883cf4c95439e6
https://doi.org/10.1002/dta.3047

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Comprehensive characterization of the peroxisome proliferator activated receptor‐δ agonist GW501516 for horse doping control analysis

Autor: Ludovic Bailly-Chouriberry, Stéphane Trevisiol, Marie-Agnès Popot, François Andre, Patrice Garcia, Yves Moulard, Laura Drif, Benoit Loup, Sophie Tendon, Benjamin Chabot, Sophie Boyer, Mylène Caroff, Vivian Delcourt, Murielle Jaubert, Wafek Taleb, Hayate Haryouli

Publikováno v: Drug Testing and Analysis. 13:1191-1202

According to international sport institutions, the use of peroxisome proliferator activated receptor (PPAR)-δ agonists is forbidden at any time in athlete career due to their capabilities to increase physical and endurance performances. The (PPAR)-�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e56734276e587645ec9b4ba583167e1
https://doi.org/10.1002/dta.3013

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An innovative derivatization‐free IC‐MS/MS method for the detection of bisphosphonates in horse plasma

Autor: Xavier Deruy, Justine Pinètre, Vivian Delcourt, Benoit Loup, Patrice Garcia, Isabelle Perot, Ludovic Bailly-Chouriberry, Murielle Jaubert, Sylvain Morel, Marie-Agnès Popot

Publikováno v: Drug Testing and Analysis. 12:1452-1461

Bisphosphonates are prohibited drugs according to Article 6 of the International Agreement on Breeding, Racing and Wagering of the International Federation of Horseracing Authorities (IFHA) and the International Equestrian Federation (FEI). These com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406d85dfb062972b02b6b5b2d12a0fc1
https://doi.org/10.1002/dta.2892

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Screening and confirmatory analysis of recombinant human erythropoietin for racing camels' doping control

Autor: Ludovic Bailly-Chouriberry, Benjamin Chabot, Patrice Garcia, Marie-Agnès Popot, Benoit Loup, Vivian Delcourt, Pierre Remy

Publikováno v: Drug Testing and Analysis. 12:763-770

Recombinant human erythropoietin (rHuEPO) belongs to the therapeutic class of erythropoiesis stimulating agents (ESAs) due to its implication in the creation pathway of red blood cells and thus enhancement of oxygenation. Because of this bioactivity,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c1aef12367a5cb2805db892f15f38b
https://doi.org/10.1002/dta.2772

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