Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Benoit, Ladoux"'
Autor:
Lakshmi Balasubramaniam, Shreyansh Jain, Tien Dang, Emilie Lagoutte, René Marc Mège, Philippe Chavrier, Benoit Ladoux, Carine Rossé
Publikováno v:
Advanced Science, Vol 11, Iss 42, Pp n/a-n/a (2024)
Abstract In vertebrates, many organs, such as the kidney and the mammary gland form ductal structures based on the folding of epithelial sheets. The development of these organs relies on coordinated sorting of different cell lineages in both time and
Externí odkaz:
https://doaj.org/article/f6c0870daab348b3a10eb897b0fb4a6e
Autor:
Thibault Bertrand, Joseph d'Alessandro, Ananyo Maitra, Shreyansh Jain, Barbara Mercier, René-Marc Mège, Benoit Ladoux, Raphaël Voituriez
Publikováno v:
Physical Review Research, Vol 6, Iss 2, p 023022 (2024)
Collective cell migration plays an essential role in various biological processes, such as development or cancer proliferation. While cell-cell interactions are clearly key determinants of collective cell migration, the physical mechanisms that contr
Externí odkaz:
https://doaj.org/article/56fbb87fa21047d28d8e62d6f884c7ed
Autor:
Serena Petracchini, Daniel Hamaoui, Anne Doye, Atef Asnacios, Florian Fage, Elisa Vitiello, Martial Balland, Sebastien Janel, Frank Lafont, Mukund Gupta, Benoit Ladoux, Jerôme Gilleron, Teresa M. Maia, Francis Impens, Laurent Gagnoux-Palacios, Mads Daugaard, Poul H. Sorensen, Emmanuel Lemichez, Amel Mettouchi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Uropathogenic strains of Escherichia coli (UPEC) are a leading cause of urinary tract infections (UTIs) and invasion involves Rho GTPase members, notably Rac1, to drive actin cytoskeleton rearrangement leading to engulfment. Here, Petracchini et al.
Externí odkaz:
https://doaj.org/article/1958110237ff42f391f49c167f39e785
Autor:
Cécile Gaston, Simon De Beco, Bryant Doss, Meng Pan, Estelle Gauquelin, Joseph D’Alessandro, Chwee Teck Lim, Benoit Ladoux, Delphine Delacour
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
The organization and force-generating property of actomyosin dictate the plasticity and behaviour of cells but the spatio-temporal regulation of this network is unclear. Here, the authors show that coupling between EpCAM/RhoA co-trafficking and actom
Externí odkaz:
https://doaj.org/article/7b55341483d34cfa93325ca1970195c7
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Collective epithelial behaviours are studied in vitro in the context of flat sheets but a system to mimic tubular systems is lacking. Here, the authors develop a method to study collective behaviour in lumenal structures and show that several feature
Externí odkaz:
https://doaj.org/article/1f288a5a0cd14208938269806004e423
Autor:
Julie Salomon, Cécile Gaston, Jérémy Magescas, Boris Duvauchelle, Danielle Canioni, Lucie Sengmanivong, Adeline Mayeux, Grégoire Michaux, Florence Campeotto, Julie Lemale, Jérôme Viala, Françoise Poirier, Nicolas Minc, Jacques Schmitz, Nicole Brousse, Benoit Ladoux, Olivier Goulet, Delphine Delacour
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
EpCAM is an unconventional epithelia-specific cell–cell adhesion molecule, that is mutated in the majority of cases of Congenital Tufting Enteropathy. Here the authors show that loss of EpCAM causes a concentration of contractile activity at tricel
Externí odkaz:
https://doaj.org/article/524637c6ef354cce802fe1c89c4f312d
Autor:
Mélina L Heuzé, Gautham Hari Narayana Sankara Narayana, Joseph D'Alessandro, Victor Cellerin, Tien Dang, David S Williams, Jan CM Van Hest, Philippe Marcq, René-Marc Mège, Benoit Ladoux
Publikováno v:
eLife, Vol 8 (2019)
Adherens junction (AJ) assembly under force is essential for many biological processes like epithelial monolayer bending, collective cell migration, cell extrusion and wound healing. The acto-myosin cytoskeleton acts as a major force-generator during
Externí odkaz:
https://doaj.org/article/3ff3dd2112464339a2c249b66c8ac43f
Autor:
Takumi Kawaue, Ivan Yow, Yuping Pan, Anh Phuong Le, Yuting Lou, Mavis Loberas, Murat Shagirov, Xiang Teng, Jacques Prost, Tetsuya Hiraiwa, Benoit Ladoux, Yusuke Toyama
Publikováno v:
Dev Cell
The number of cells in tissues is controlled by cell division and cell death, and its misregulation could lead to pathological conditions such as cancer. To maintain the cell numbers, a cell-elimination process called apoptosis also stimulates the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10484bc6cd89f47f1d5cc11ad6f4faf5
https://europepmc.org/articles/PMC7614677/
https://europepmc.org/articles/PMC7614677/
Publikováno v:
Current Opinion in Cell Biology. 72:54-62
Collective cell migration is crucial to maintain epithelium integrity during developmental and repair processes. It requires a tight regulation of mechanical coordination between neighboring cells. This coordination embraces different features includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea22530a68bf576f5e010d4804eb651
https://doi.org/10.1016/j.ceb.2021.04.006
https://doi.org/10.1016/j.ceb.2021.04.006
Autor:
Estelle Gauquelin, Meng Pan, Benoit Ladoux, Cécile Gaston, Chwee Teck Lim, Bryant L. Doss, Simon de Beco, Delphine Delacour, Joseph D'Alessandro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12, ⟨10.1038/s41467-021-22482-9⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12, ⟨10.1038/s41467-021-22482-9⟩
At the basis of cell shape and behavior, the organization of actomyosin and its ability to generate forces are widely studied. However, the precise regulation of this contractile network in space and time is unclear. Here, we study the role of the ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff7c0866eedd20d146e04807b56c4f0
https://doaj.org/article/7b55341483d34cfa93325ca1970195c7
https://doaj.org/article/7b55341483d34cfa93325ca1970195c7