Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Benoît Villiers"'
Autor:
Annica Saaret, Benoît Villiers, François Stricher, Macha Anissimova, Mélodie Cadillon, Reynard Spiess, Sam Hay, David Leys
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Isobutene is a high value gaseous alkene that is widely used as fuel additive and a chemical building block. Here, the authors report an alternative pathway for isobutene bioproduction by directed evolution of prenylated FMN-dependent ferulic acid de
Externí odkaz:
https://doaj.org/article/d96751d628eb4409a64c70cfafc944c0
Autor:
Thu Lan Nguyen, Arnaud Duchon, Antigoni Manousopoulou, Nadège Loaëc, Benoît Villiers, Guillaume Pani, Meltem Karatas, Anna E. Mechling, Laura-Adela Harsan, Emmanuelle Limanton, Jean-Pierre Bazureau, François Carreaux, Spiros D. Garbis, Laurent Meijer, Yann Herault
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
Growing evidence supports the implication of DYRK1A in the development of cognitive deficits seen in Down syndrome (DS) and Alzheimer's disease (AD). We here demonstrate that pharmacological inhibition of brain DYRK1A is able to correct recognition m
Externí odkaz:
https://doaj.org/article/e16e12f9d89c402a95c465eec377aa80
Autor:
Nadège Loaëc, Eletta Attanasio, Benoît Villiers, Emilie Durieu, Tania Tahtouh, Morgane Cam, Rohan A. Davis, Aline Alencar, Mélanie Roué, Marie-Lise Bourguet-Kondracki, Peter Proksch, Emmanuelle Limanton, Solène Guiheneuf, François Carreaux, Jean-Pierre Bazureau, Michelle Klautau, Laurent Meijer
Publikováno v:
Marine Drugs, Vol 15, Iss 10, p 316 (2017)
A large diversity of 2-aminoimidazolone alkaloids is produced by various marine invertebrates, especially by the marine Calcareous sponges Leucetta and Clathrina. The phylogeny of these sponges and the wide scope of 2-aminoimidazolone alkaloids they
Externí odkaz:
https://doaj.org/article/7e666c8e31a446ceb50468639baa1681
Autor:
Tania Tahtouh, Emilie Durieu, Benoît Villiers, Céline Bruyère, Thu Lan Nguyen, Xavier Fant, Kwang H. Ahn, Leepakshi Khurana, Emmanuel Deau, Mattias F. Lindberg, Elodie Sévère, Frédéric Miege, Didier Roche, Emmanuelle Limanton, Jean-Martial L’Helgoual’ch, Guillaume Burgy, Solène Guiheneuf, Yann Herault, Debra A. Kendall, François Carreaux, Jean-Pierre Bazureau, Laurent Meijer
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2022, ⟨10.1021/acs.jmedchem.1c01141⟩
Journal of Medicinal Chemistry, 2022, 65 (2), pp.1396-1417. ⟨10.1021/acs.jmedchem.1c01141⟩
Journal of Medicinal Chemistry, American Chemical Society, 2022, ⟨10.1021/acs.jmedchem.1c01141⟩
Journal of Medicinal Chemistry, 2022, 65 (2), pp.1396-1417. ⟨10.1021/acs.jmedchem.1c01141⟩
International audience; The protein kinase DYRK1A is involved in Alzheimer's disease, Down syndrome, diabetes, viral infections, and leukemia. Leucettines, a family of 2-aminoimidazolin-4-ones derived from the marine sponge alkaloid Leucettamine B, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b69d0950240f3edb4ed4b932320217
Autor:
Reynard Spiess, François Stricher, Sam Hay, Annica Saaret, David Leys, Macha Anissimova, Mélodie Cadillon, Benoît Villiers
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Isobutene is a high value gaseous alkene used as fuel additive and a chemical building block. As an alternative to fossil fuel derived isobutene, we here develop a modified mevalonate pathway for the production of isobutene from glucose in vivo. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef70d87b510086aeef012e42741b9985