Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Benoît S. Marteyn"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
More than two decades after cloning the cystic fibrosis transmembrane regulator (CFTR) gene, the defective gene in cystic fibrosis (CF), we still do not understand how dysfunction of this ion channel causes lung disease and the tremendous neutrophil
Externí odkaz:
https://doaj.org/article/18c4640a463b44d2a5dc388099bcac6c
Autor:
Shin-San Michael Su, Scott A. Biller, Virginie Penard-Lacronique, Marion Dorsch, Lenny Dang, Hua Yang, Wei Liu, Lee Silverman, Shengfang Jin, Wentao Wei, Fan Jiang, Cheng Fang, YingXia Xu, Monika Pilichowska, Benoît S. Marteyn, Stéphane de Botton, Olivier A. Bernard, Sophie Broutin, Angelo Paci, Véronique Saada, Olivia Bawa, Paule Opolon, Cyril Quivoron, Francesco G. Salituro, Jeffrey O. Saunders, Giovanni Cianchetta, Zenon Konteatis, Lei Jin, Sung Choe, Raj Nagaraja, Yue Chen, Erica Tobin, Byron DeLaBarre, Stefan Gross, Anil Padyana, Kimberly Straley, Erin Artin, Muriel D. David, Fang Wang, Jeremy Travins, Katharine Yen
Supplementary Figure 1. Synthesis and pharmacokinetic characterization of AG-221. Supplementary Figure 2. Biochemical attributes of AG-221. Supplementary Figure 3. Biochemistry of AG-221 with respect to substrate and cofactor. Supplementary Figure 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d97954935b2f34d5dfe50e66a1f7f5
https://doi.org/10.1158/2159-8290.22531945.v1
https://doi.org/10.1158/2159-8290.22531945.v1
Autor:
Shin-San Michael Su, Scott A. Biller, Virginie Penard-Lacronique, Marion Dorsch, Lenny Dang, Hua Yang, Wei Liu, Lee Silverman, Shengfang Jin, Wentao Wei, Fan Jiang, Cheng Fang, YingXia Xu, Monika Pilichowska, Benoît S. Marteyn, Stéphane de Botton, Olivier A. Bernard, Sophie Broutin, Angelo Paci, Véronique Saada, Olivia Bawa, Paule Opolon, Cyril Quivoron, Francesco G. Salituro, Jeffrey O. Saunders, Giovanni Cianchetta, Zenon Konteatis, Lei Jin, Sung Choe, Raj Nagaraja, Yue Chen, Erica Tobin, Byron DeLaBarre, Stefan Gross, Anil Padyana, Kimberly Straley, Erin Artin, Muriel D. David, Fang Wang, Jeremy Travins, Katharine Yen
Supplementary Table 1. Drug metabolism and pharmacokinetic attributes of AG-221. Supplementary Table 2. Selectivity of AG-221 confirmed by testing against a panel of kinases. Supplementary Table 3. Clinical characteristics of patients with IDH2R140Q-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd472a11c8ff29b3f26438ea494ea5d
https://doi.org/10.1158/2159-8290.22531936
https://doi.org/10.1158/2159-8290.22531936
Autor:
Shin-San Michael Su, Scott A. Biller, Virginie Penard-Lacronique, Marion Dorsch, Lenny Dang, Hua Yang, Wei Liu, Lee Silverman, Shengfang Jin, Wentao Wei, Fan Jiang, Cheng Fang, YingXia Xu, Monika Pilichowska, Benoît S. Marteyn, Stéphane de Botton, Olivier A. Bernard, Sophie Broutin, Angelo Paci, Véronique Saada, Olivia Bawa, Paule Opolon, Cyril Quivoron, Francesco G. Salituro, Jeffrey O. Saunders, Giovanni Cianchetta, Zenon Konteatis, Lei Jin, Sung Choe, Raj Nagaraja, Yue Chen, Erica Tobin, Byron DeLaBarre, Stefan Gross, Anil Padyana, Kimberly Straley, Erin Artin, Muriel D. David, Fang Wang, Jeremy Travins, Katharine Yen
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf9f6f1fb6d2a1049263137b504fc3a
https://doi.org/10.1158/2159-8290.22531939
https://doi.org/10.1158/2159-8290.22531939
Autor:
P. Malaka De Silva, Rebecca J. Bennett, Lauriane Kuhn, Patryk Ngondo, Lorine Debande, Elisabeth Njamkepo, Brian Ho, François-Xavier Weill, Benoît S. Marteyn, Claire Jenkins, Kate Baker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a42e1e720a2e719063ecab4139b1e66
https://doi.org/10.2139/ssrn.4318406
https://doi.org/10.2139/ssrn.4318406
Autor:
Jurate Skerniskyte, Céline Mulet, Antonin C. André, Mark C. Anderson, Louise Injarabian, Achim Buck, Verena M. Prade, Philippe J. Sansonetti, Sophie Reibel-Foisset, Axel K. Walch, Michel Lebel, Jens Lykkesfeldt, Benoit S. Marteyn
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTShigella spp. are the causative agents of bacterial dysentery and shigellosis, mainly in children living in developing countries. The study of Shigella entire life cycle in vivo and the evaluation of vaccine candidates’ protective efficacy
Externí odkaz:
https://doaj.org/article/89d9b94eee7e4f86934d999908bc40af
Autor:
Katharine, Yen, Jeremy, Travins, Fang, Wang, Muriel D, David, Erin, Artin, Kimberly, Straley, Anil, Padyana, Stefan, Gross, Byron, DeLaBarre, Erica, Tobin, Yue, Chen, Raj, Nagaraja, Sung, Choe, Lei, Jin, Zenon, Konteatis, Giovanni, Cianchetta, Jeffrey O, Saunders, Francesco G, Salituro, Cyril, Quivoron, Paule, Opolon, Olivia, Bawa, Véronique, Saada, Angelo, Paci, Sophie, Broutin, Olivier A, Bernard, Stéphane, de Botton, Benoît S, Marteyn, Monika, Pilichowska, YingXia, Xu, Cheng, Fang, Fan, Jiang, Wentao, Wei, Shengfang, Jin, Lee, Silverman, Wei, Liu, Hua, Yang, Lenny, Dang, Marion, Dorsch, Virginie, Penard-Lacronique, Scott A, Biller, Shin-San Michael, Su
Publikováno v:
Cancer discovery. 7(5)
AG-221 or enasidenib is a first-in-class selective inhibitor of mutated isocitrate dehydrogenase 2 (IDH2) with early demonstrated clinical efficacy in acute myeloid leukemia as a single agent, yet with persistence of mutant IDH2 clones. Two papers in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d30618427a82a8efe6855ead5edc951
https://pubmed.ncbi.nlm.nih.gov/28461409
https://pubmed.ncbi.nlm.nih.gov/28461409
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 287 (2019)
Polymorphonuclear neutrophils (PMNs) are innate immune cells, which represent 50% to 70% of the total circulating leukocytes. How PMNs adapt to various microenvironments encountered during their life cycle, from the bone marrow, to the blood plasma f
Externí odkaz:
https://doaj.org/article/651d9a81041e4043bac87d8a98b3da0c
Autor:
Benoit S. Marteyn, Gouzel Karimova, Andrew K. Fenton, Anastasia D. Gazi, Nicholas West, Lhousseine Touqui, Marie-Christine Prevost, Jean-Michel Betton, Oemer Poyraz, Daniel Ladant, Kenn Gerdes, Philippe J. Sansonetti, Christoph M. Tang
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT Bacterial cell division requires the formation of a mature divisome complex positioned at the midcell. The localization of the divisome complex is determined by the correct positioning, assembly, and constriction of the FtsZ ring (Z-ring). Z
Externí odkaz:
https://doaj.org/article/09defa5ffaca4dcfae9eb606c7f4b51b