Identification of common predisposing loci to hematopoietic cancers in four dog breeds.

Autor: Benoît Hédan, Édouard Cadieu, Maud Rimbault, Amaury Vaysse, Caroline Dufaure de Citres, Patrick Devauchelle, Nadine Botherel, Jérôme Abadie, Pascale Quignon, Thomas Derrien, Catherine André

Publikováno v: PLoS Genetics, Vol 17, Iss 4, p e1009395 (2021)

Histiocytic sarcoma (HS) is a rare but aggressive cancer in both humans and dogs. The spontaneous canine model, which has clinical, epidemiological, and histological similarities with human HS and specific breed predispositions, provides a unique opp

Externí odkaz: https://doaj.org/article/83b7aa5c05f74840a40c12c3ffd16bc1

Table S2 from Discovery of Human-Similar Gene Fusions in Canine Cancers

Autor: Catherine André, Benoît Hédan, Thomas Derrien, Arnaud Le Goff, Thierry Guillaudeux, Benoit Hennuy, David Gilot, Laura Bachelot, Florian Cabillic, Laurence Cornevin, Christophe Hitte, Catherine Thieblemont, Edouard Cadieu, Valentin Wucher, Audrey Rousseau, Nadine Botherel, Jean-Michel Coindre, Clotilde De Brito, Jérôme Abadie, Laetitia Lagoutte, Mathieu Bahin, Mélanie Rault, Ronan Ulvé

Primers used for validation of the canine gene fusions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5b2d2b867e71fa4b92c97f7959272f
https://doi.org/10.1158/0008-5472.22418496

Genomic Diversity and Runs of Homozygosity in Bernese Mountain Dogs

Autor: Anna Letko, Benoît Hédan, Anna Snell, Alexander C. Harris, Vidhya Jagannathan, Göran Andersson, Bodil S. Holst, Elaine A. Ostrander, Pascale Quignon, Catherine André, Tosso Leeb

Publikováno v: Genes
Genes, 2023, 14 (3), ⟨10.3390/genes14030650⟩
Volume 14
Issue 3
Pages: 650
Letko, Anna; Hédan, Benoît; Snell, Anna; Harris, Alexander C; Jagannathan, Vidhya; Andersson, Göran; Holst, Bodil S; Ostrander, Elaine A; Quignon, Pascale; André, Catherine; Leeb, Tosso (2023). Genomic Diversity and Runs of Homozygosity in Bernese Mountain Dogs. Genes, 14(3) MDPI, Molecular Diversity Preservation International 10.3390/genes14030650

International audience; Bernese mountain dogs are a large dog breed formed in the early 1900s in Switzerland. While originally farm dogs that were used for pulling carts, guarding, and driving cattle, today they are considered multi-purpose companion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf989161125248b224457090adcd5c91
https://hal.science/hal-04100178

Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits

Autor: Judith Lorant, Thibaut Larcher, Nicolas Jaulin, Benoît Hedan, Aurélie Lardenois, Isabelle Leroux, Laurence Dubreil, Mireille Ledevin, Hélicia Goubin, Sophie Moullec, Jack-Yves Deschamps, Chantal Thorin, Catherine André, Oumeya Adjali, Karl Rouger

Publikováno v: Cell Transplantation, Vol 27 (2018)

Growing demonstrations of regenerative potential for some stem cells led recently to promising therapeutic proposals for neuromuscular diseases. We have shown that allogeneic MuStem cell transplantation into Golden Retriever muscular dystrophy (GRMD)

Externí odkaz: https://doaj.org/article/94c2e7d00d8d4b60b00dad13e3e6a9ea

Canine population structure: assessment and impact of intra-breed stratification on SNP-based association studies.

Autor: Pascale Quignon, Laetitia Herbin, Edouard Cadieu, Ewen F Kirkness, Benoit Hédan, Dana S Mosher, Francis Galibert, Catherine André, Elaine A Ostrander, Christophe Hitte

Publikováno v: PLoS ONE, Vol 2, Iss 12, p e1324 (2007)

In canine genetics, the impact of population structure on whole genome association studies is typically addressed by sampling approximately equal numbers of cases and controls from dogs of a single breed, usually from the same country or geographic a

Externí odkaz: https://doaj.org/article/999d0a5aed364479a1f91aeaad414180