Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Benoît, Biteau"'
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010385 (2022)
Stem cells are essential for the development and long-term maintenance of tissues and organisms. Preserving tissue homeostasis requires exquisite control of all aspects of stem cell function: cell potency, proliferation, fate decision and differentia
Externí odkaz:
https://doaj.org/article/f4c53847b9774d62801dff3d6de44311
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 226-240 (2020)
Summary: Robust production of terminally differentiated cells from self-renewing resident stem cells is essential to maintain proper tissue architecture and physiological functions, especially in high-turnover tissues. However, the transcriptional ne
Externí odkaz:
https://doaj.org/article/ca0d50be66804f898d97d476b50e326b
Autor:
Benoît Biteau
Publikováno v:
DARD/DARD. :40-51
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008553 (2019)
Many tissues rely on resident stem cell population to maintain homeostasis. The balance between cell proliferation and differentiation is critical to permit tissue regeneration and prevent dysplasia, particularly following tissue damage. Thus, unders
Externí odkaz:
https://doaj.org/article/4781e34681e848e283b1f4832b964034
Autor:
Fanju W. Meng, Benoît Biteau
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 906-914 (2015)
Adult organs and their resident stem cells are constantly facing the challenge of adapting cell proliferation to tissue demand, particularly in response to environmental stresses. Whereas most stress-signaling pathways are conserved between progenito
Externí odkaz:
https://doaj.org/article/78858223473c45e19e538d639167f36f
Autor:
Benoît Biteau, Heinrich Jasper
Publikováno v:
Cell Reports, Vol 7, Iss 6, Pp 1867-1875 (2014)
In order to maintain tissue homeostasis, cell fate decisions within stem cell lineages have to respond to the needs of the tissue. This coordination of lineage choices with regenerative demand remains poorly characterized. Here, we identify a signal
Externí odkaz:
https://doaj.org/article/62f16b074a0441c69053143427db099c
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 226-240 (2020)
Stem Cell Reports
Stem Cell Reports
Summary Robust production of terminally differentiated cells from self-renewing resident stem cells is essential to maintain proper tissue architecture and physiological functions, especially in high-turnover tissues. However, the transcriptional net
Publikováno v:
Aging (Albany NY)
Age-related decline in stem cell function is observed in many tissues from invertebrates to humans. While cell intrinsic alterations impair stem cells, aging of the stem cell niche also significantly contributes to the loss of tissue homeostasis asso
Autor:
Benoît Biteau, Jason Karpac, Stephen Supoyo, Matthew Degennaro, Ruth Lehmann, Heinrich Jasper
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001159 (2010)
Regenerative processes are critical to maintain tissue homeostasis in high-turnover tissues. At the same time, proliferation of stem and progenitor cells has to be carefully controlled to prevent hyper-proliferative diseases. Mechanisms that ensure t
Externí odkaz:
https://doaj.org/article/8ff7f2b5a1e4437aae0ecd9e5e106edd
Publikováno v:
Developmental Biology. 426:8-16
Adult stem cell proliferation rates are precisely regulated to maintain long-term tissue homeostasis. Defects in the mechanisms controlling stem cell proliferation result in impaired regeneration and hyperproliferative diseases. Many stem cell popula