Výsledky vyhledávání - "Benny P. Shum"

Conserved organization of the ILT / LIR gene family within the polymorphic human leukocyte receptor complex

Autor: Neil Thomas Young, Benny P. Shum, Flavio Canavez, Markus Uhrberg, Peter Parham

Publikováno v: Immunogenetics. 53:270-278

The human leukocyte receptor complex (LRC) at Chromosome 19q13.4 encodes Ig superfamily proteins which regulate the function of various hematopoietic cell types. We investigated characteristics of the Ig-like transcript (ILT)/leukocyte Ig-like recept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab11ee3e447a62da257f6800de2c744f
https://doi.org/10.1007/s002510100332

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Short KIR Haplotypes in Pygmy Chimpanzee (Bonobo) Resemble the Conserved Framework of Diverse Human KIR Haplotypes

Autor: Lisbeth A. Guethlein, Benny P. Shum, Mei Hong, Erin J. Adams, Peter Parham, Raja Rajalingam

Publikováno v: The Journal of Experimental Medicine
The Journal of experimental medicine, vol 193, iss 1

Some pygmy chimpanzees (also called Bonobos) give much simpler patterns of hybridization on Southern blotting with killer cell immunoglobulin-like receptor (KIR) cDNA probes than do either humans or common chimpanzees. Characterization of KIRs from p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352b8118c2cec77aa0b9c5c4de00d810
http://europepmc.org/articles/PMC2195888

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Residue 3 of β 2 -microglobulin affects binding of class I MHC molecules by the W6/32 antibody

Autor: Peter Parham, Benny P. Shum, Héctor N. Seuánez, John J. Ladasky, Flavio Canavez

Publikováno v: Immunogenetics. 49:312-320

Previous studies of class I MHC molecules have shown that the owl monkey (Aotus) possesses at least two variants of the beta2-microglobulin (beta2m) protein. These two variants have different isoelectric points, and exhibit differential reactivity wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85854dfd3611651f17775d3670c51549
https://doi.org/10.1007/s002510050498

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Human Diversity in Killer Cell Inhibitory Receptor Genes

Autor: Dolly B. Tyan, Brian Corliss, Lewis L. Lanier, Markus Uhrberg, Heather G. Shilling, Benny P. Shum, Nicholas Valiante, Peter Parham, K. Lienert-Weidenbach

Publikováno v: Immunity. 7:753-763

The presence and expression of killer inhibitory receptor (KIR) and CD94:NKG2 genes from 68 donors were analyzed using molecular typing techniques. The genes encoding CD94:NKG2 receptors were present in each person, but KIR gene possession varied. Mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ef03e591cc5651811ae9343aec3ae3
https://doi.org/10.1016/s1074-7613(00)80394-5

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The beta 2-microglobulin locus of rainbow trout (Oncorhynchus mykiss) contains three polymorphic genes

Autor: Peter Parham, Benny P. Shum, Katharine E. Magor

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 172(6)

β2-microglobulin (β2m) associates with MHC and related class I H chains to form cell surface glycoproteins that mediate a variety of functions in defense. In humans, monomorphism of a single β2m gene contrasts with the diversity and polymorphism o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da280f469790e29e1a3eb941d1afb18f
https://pubmed.ncbi.nlm.nih.gov/15004166

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Structures of two major histocompatibility complex class I genes of the rainbow trout (Oncorhynchus mykiss)

Autor: Patricia M. Mason, Katharine E. Magor, René J. M. Stet, Laura R. Flodin, Peter Parham, Benny P. Shum

Publikováno v: Immunogenetics 54 (2002)
Immunogenetics, 54, 193-199

Here we describe two rainbow trout major histocompatibility complex (MHC) class I genes characterized from lambda phage genomic clones prepared from a single fish. Clone GC71 contains all exons except a leader peptide-encoding exon. An open reading f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4499fb1cd9bb9a61d6cb70b996aaac
https://research.wur.nl/en/publications/structures-of-two-major-histocompatibility-complex-class-i-genes-

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Unique haplotypes of co-segregating major histocompatibility class II A and class II B alleles in Atlantic salmon (Salmo salar) give rise to diverse class II genotypes

Autor: Unni Grimholt, Benny P. Shum, Beja J de Vries, Karin Mudde, René J. M. Stet, Trudi Hermsen, Joost van Heerwaarden

Publikováno v: Immunogenetics, 54, 320-331
Immunogenetics 54 (2002)

Sequence-based typing of a breeding population (G1) consisting of 84 Atlantic salmon individuals revealed the presence of 7 Sasa-DAA and 7 Sasa-DAB expressed alleles. Subsequent typing of 1,182 individuals belonging to 33 families showed that Sasa-DA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85cde64d83a2cae06396759d522a2fb
https://research.wur.nl/en/publications/unique-haplotypes-of-co-segregating-major-histocompatibility-clas

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Conservation and variation in human and common chimpanzee CD94 and NKG2 genes

Autor: Salim I. Khakoo, Raja Rajalingam, Laura R. Flodin, Benny P. Shum, Markus Uhrberg, Lisabeth A. Guethlein, David G. Muir, Peter Parham, Sophia Cleland

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 168(1)

To assess polymorphism and variation in human and chimpanzee NK complex genes, we determined the coding-region sequences for CD94 and NKG2A, C, D, E, and F from several human (Homo sapiens) donors and common chimpanzees (Pan troglodytes). CD94 is hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57951e135efb207f5ccc0efd4ae9c7db
https://pubmed.ncbi.nlm.nih.gov/11751968

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