Výsledky vyhledávání - "Benny Howard"

Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing

Autor: Benny Howard, Kelsey E. Monteith, Rakhee Banerjee, Peter J. Harte, Feng Tie, Peter C. Scacheri, Alina Saiakhova, Michael S. Cosgrove

Publikováno v: Development. 141:1129-1139

Trithorax (TRX) antagonizes epigenetic silencing by Polycomb group (PcG) proteins, stimulates enhancer-dependent transcription, and establishes a ‘cellular memory’ of active transcription of PcG-regulated genes. The mechanisms underlying these TR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3506ec48c7eb5f25f7863da9083a3957
https://doi.org/10.1242/dev.102392

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Automethylation Activities within the Mixed Lineage Leukemia-1 (MLL1) Core Complex Reveal Evidence Supporting a 'Two-active Site' Model for Multiple Histone H3 Lysine 4 Methylation

Autor: Venkatasubramanian Dharmarajan, Benny Howard, Gillian V. Kupakuwana, Stephen A. Shinsky, Michael S. Cosgrove, Stephen Swatkoski, Anamika Patel, Valarie E. Vought, Susan Viggiano, Robert J. Cotter, Kelsey E. Monteith, Kevin E. Namitz

Publikováno v: The Journal of Biological Chemistry

Background: The MLL1 core complex mono- and dimethylates histone H3 lysine 4 (H3K4). Results: MLL1 automethylates a conserved cysteine residue in its active site cleft. Conclusion: MLL1 automethylation is inhibited by unmodified histone H3 but not by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f7e8cd65ee4e7c24a58eb71f3d63a7
https://doi.org/10.1074/jbc.m113.501064

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Fusion of mApple and Venus fluorescent proteins to the Sindbis virus E2 protein leads to different cell-binding properties

Autor: Benny Howard, Irina B. Tsvetkova, Xiang Ma, Fan Cheng, Suchetana Mukhopadhyay, Alan Moore, Bogdan Dragnea

Publikováno v: Virus Research. 177:138-146

Fluorescent proteins (FPs) are widely used in real-time single virus particle studies to visualize, track and quantify the spatial and temporal parameters of viral pathways. However, potential functional differences between the wild type and the FP-t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a4a220deb318f99883fa49522b2da9
https://doi.org/10.1016/j.virusres.2013.07.014

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