Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Benny H. Chang"'
Autor:
Koki Mise, Jianyin Long, Daniel L. Galvan, Zengchun Ye, Guizhen Fan, Rajesh Sharma, Irina I. Serysheva, Travis I. Moore, Collene R. Jeter, M. Anna Zal, Motoo Araki, Jun Wada, Paul T. Schumacker, Benny H. Chang, Farhad R. Danesh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The mitochondrial electron transport chain (ETC) is a highly adaptive process to meet metabolic demands of the cell, and its dysregulation has been associated with diverse clinical pathologies. However, the role and nature of impaired ETC in
Externí odkaz:
https://doaj.org/article/453171ce7f1542cba93f5b45df627a2b
Autor:
Zhouji Chen, Shiyu Wang, Anita Pottekat, Alec Duffey, Insook Jang, Benny H. Chang, Jaehyung Cho, Brian N. Finck, Nicholas O. Davidson, Randal J. Kaufman
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101874- (2024)
Objectives: The assembly and secretion of hepatic very low-density lipoprotein (VLDL) plays pivotal roles in hepatic and plasma lipid homeostasis. Protein disulfide isomerase A1 (PDIA1/P4HB) is a molecular chaperone whose functions are essential for
Externí odkaz:
https://doaj.org/article/2eb00029f7a54fa383e62a065aa4cf9b
Autor:
Koki Mise, Jianyin Long, Daniel L. Galvan, Zengchun Ye, Guizhen Fan, Rajesh Sharma, Irina I. Serysheva, Travis I. Moore, Collene R. Jeter, M. Anna Zal, Motoo Araki, Jun Wada, Paul T. Schumacker, Benny H. Chang, Farhad R. Danesh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/c4f100e58c874f5c8dae224ec3a84966
Autor:
Li Li, Jianyin Long, Koki Mise, Daniel L. Galvan, Paul A. Overbeek, Lin Tan, Shwetha V. Kumar, Wai Kin Chan, Phillip L. Lorenzi, Benny H. Chang, Farhad R. Danesh
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109510- (2021)
Summary: lncRNA taurine-upregulated gene 1 (Tug1) is a promising therapeutic target in the progression of diabetic nephropathy (DN), but the molecular basis of its protection remains poorly understood. Here, we generate a triple-mutant diabetic mouse
Externí odkaz:
https://doaj.org/article/a3b8d8c7911041b184af86ff25e76572
Autor:
Shawn S. Badal, Yin Wang, Jianyin Long, David L. Corcoran, Benny H. Chang, Luan D. Truong, Yashpal S. Kanwar, Paul A. Overbeek, Farhad R. Danesh
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Podocyte injury is central to kidney dysfunction in diabetic nephropathy. Here the authors show that Msk2 is a target of miR-93 and this interaction mediates pathogenic chromatin remodelling in diabetic nephropathy.
Externí odkaz:
https://doaj.org/article/1ce001af6cd14a0591eb2b966bb36301
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181046 (2017)
Previous studies in our laboratory have established the presence of MTP in both white and brown adipose tissue in mice as well as in 3T3-L1 cells. Additional studies demonstrated an increase in MTP levels as 3T3-L1 cells differentiate into adipocytes
Externí odkaz:
https://doaj.org/article/bf4019adc011449abff4ebb4fa56ce86
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33063 (2012)
Interventions on macrophages/foam cells to redirect intracellular cholesterol towards efflux pathways could become a very valuable addition to our therapeutic arsenal against atherosclerosis. However, certain manipulations of the cholesteryl ester cy
Externí odkaz:
https://doaj.org/article/fc05797f2e2e4e8a90d338ff38ca81cc
Autor:
Daniel L. Galvan, Luan D. Truong, Paul A. Overbeek, Benny H. Chang, Jianyin Long, Nathanael Green, Paul T. Schumacker, Farhad R. Danesh, Jamie S. Lin
Publikováno v:
The Journal of clinical investigation. 129(7)
Phosphorylation of dynamin-related protein 1 (Drp1) represents an important regulatory mechanism for mitochondrial fission. Here, we established the role of Drp1 serine 600 (Drp1S600) phosphorylation in mitochondrial fission in vivo and assessed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc410abecf7a4d17819e7800c293e25a
https://pubmed.ncbi.nlm.nih.gov/31063459
https://pubmed.ncbi.nlm.nih.gov/31063459